Results 81 to 90 of about 1,579,823 (328)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Monocular 3D Micro-PIV System Using Computational Imaging
IEEE Photonics JournalA three-dimensional (3D) particle image velocimetry (PIV) system typically consists of multiple cameras. However, micro-PIV systems for measuring microscale velocity fields lack sufficient space to accommodate them. In this work we propose an alternative
Taiyuange Lou +4 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
PhotonicsTo address the application demands of ultra-wide-field optical systems, we developed a compact, long-infrared waveband optical system using a field-of-view (FoV) stitching method.
Yiruo Wang, Shan Mao, Jianlin Zhao
doaj +1 more source
New Optical Splitter Design for Network Scalability and Flexibility [PDF]
, 2009 In this paper, we present the design of two optical splitter which are 2x3 optical splitter-combine and Multi Ratio Optical Splitter (MROS) based on waveguide with SU-8 polymer material.
Syuhaimi, Mohammad
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A novel dual-path high-throughput acousto-optic tunable filter imaging spectropolarimeter
Journal of Spectral Imaging, 2020 It is highly demanding to identify healthy and non-healthy species in a heterogeneous environment such as human tissues. In such a case, one identifier, such as a spectral fingerprint, might be inadequate. Therefore, additional identification is required,
Ramy Abdlaty, Qiyin Fang
doaj +1 more source
Linear Rotary Optical Delay Lines
, 2014 I present several classes of analytical and semi-analytical solutions for the design of high-speed rotary optical delay lines that use a combination of stationary and rotating curvilinear reflectors.
Skorobogatiy, Maksim
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
A methodical approach to design adiabatic waveguide couplers for heterogeneous integrated photonics
JPhys PhotonicsWe present an elegant and effective approach for the design of adiabatic waveguide couplers tailored for the heterogeneous integration of photonic building blocks.
Jef Van Asch +7 more
doaj +1 more source