Results 91 to 100 of about 531,434 (269)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Structure design for light‐extraction enhancement of UVC‐LED

Nano Select
UVC‐LEDs have drawn attention recently because of their benefits to sterilization, decontamination, etc. Since the internal quantum efficiency and light extraction efficiency (LEE) of UVC‐LEDs are low, their external quantum efficiency remains ...
Qixin Liu, An‐Chi Wei
doaj   +1 more source

Design of Polarization Spectroscopy Integrated Imaging System

Photonics
To simultaneously acquire the spectral and polarization information of the target and achieve the monitoring and identification of the target object, a polarization spectral integrated imaging system is proposed in this paper.
Jianan Liu, Jing Cui, Mingce Chen, Shuo Yang, Hongyu Sun, Qi Wang, Juntong Zhan, Yingchao Li, Qiang Fu, Chao Wang   +9 more
doaj   +1 more source

Long Term Clinical Outcomes of Hydrophilic and Hydrophobic Versions of a Trifocal IOL with the Same Optical Design. [PDF]

Clin Ophthalmol, 2023
Ang RET.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Optical Design of a Novel Wide-Field-of-View Space-Based Spectrometer for Climate Monitoring. [PDF]

Sensors (Basel), 2022
Schifano L, Berghmans F, Dewitte S, Smeesters L.   +3 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Compact freeform near-eye display system design enabled by optical-digital joint optimization

Frontiers in Physics
The near-eye display (NED) systems, designed to project content into the human eye, are pivotal in the realms of augmented reality (AR) and virtual reality (VR), offering users immersive experiences.
Huiming Xu, Tong Yang, Dewen Cheng, Yongtian Wang   +3 more
doaj   +1 more source

Refractive Outcome and 5-Year Capsulotomy Rate of Hydrophobic and Hydrophilic IOLs with Similar Optical Design: A Contralateral Study. [PDF]

Ophthalmol Ther, 2023
Bellucci C, Mora P, Tedesco SA, Gandolfi S, Bellucci R.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source