Results 81 to 90 of about 11,751,807 (260)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

An Optical Communication Design Laboratory [PDF]

1998 Annual Conference Proceedings, 1999
A senior-level design laboratory course is described, in which an optical fiber communication network is expanded or improved by successive generations of students. In this evolutionary approach, student teams base their work on the final written reports of students in previous course offerings. In addition to its primary goal of providing a high-level
J.P. Uyemura, J.A. Buck, H. Owen, D.J. Blumenthal, C.M. Verber   +4 more
openaire   +2 more sources

Architecture, design, and modeling of the OPSnet asynchronous optical packet switching node [PDF]

, 2005
An all-optical packet-switched network supporting multiple services represents a long-term goal for network operators and service providers alike.
Vanderbauwhede, W.A., Vanderbauwhede, W., Harle, DA, Harle, D.A., Vanderbauwhede, WA   +4 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Design and fabrication of highly efficient non-linear optical devices for implementing high-speed optical processing [PDF]

, 2002
We present the design and fabrication of micro-cavity semiconductor devices for enhanced Two-Photon-Absorption response, and demonstrate the use of these devices for implementing sensitive autocorrelation measurements on pico-second optical ...
Folliot, H., Barry, Liam P., Krug, T., Lynch, Michael, Donegan, John Francis, Hill, G., Roberts, J.S., Bradley, Ann Louise   +7 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Development and Application of Unmanned Aerial High-Resolution Convex Grating Dispersion Hyperspectral Imager

Sensors
This study presents the design and development of a high-resolution convex grating dispersion hyperspectral imaging system tailored for unmanned aerial vehicle (UAV) remote sensing applications.
Qingsheng Xue, Xinyu Gao, Fengqin Lu, Jun Ma, Junhong Song, Jinfeng Xu   +5 more
doaj   +1 more source

Design and modelling of optical microsystems

, 2022
Optical microsystems consist of micro-optical, integrated-optical, mechanical and packaging components. Due to the hybrid nature and the high complexity of these microsystems a general design strategy is required.
Reichl, H., Stock, A., Bartelt, H., Karthe, W., Elbers, J.P., Schäfer, W., Sickinger, H., Schwider, J., Schröter, S., Krabe, D., Wächter, C., Glingener, C., Hagener, G., Dümcke, R., Voges, E., Schreiber, P.   +15 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source