Results 41 to 50 of about 4,090,293 (192)

Optical High-Capacity Satellite Downlinks via High-Altitude Platform Relays [PDF]

, 2007
Earth-observation (EO) satellite missions produce a large amount of data using high-resolution optical or radar sensors. During the last decades the amount of data has steadily increased due to improved sensor technologies with increased temporal ...
Florian Moll, Bischl, Hermann, Markus Knapek, Giggenbach, Dirk, Joachim Horwath, Horwath, Joachim, Courville, Nicolas, Knapek, Markus, Bernd Epple, Moll, Florian, Nicolas Courville, Hermann Bischl, Epple, Bernhard, Dirk Giggenbach   +13 more
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Chromosome-scale assembly and annotation of the perennial ryegrass genome

BMC Genomics, 2022
Background The availability of chromosome-scale genome assemblies is fundamentally important to advance genetics and breeding in crops, as well as for evolutionary and comparative genomics.
Istvan Nagy, Elisabeth Veeckman, Chang Liu, Michiel Van Bel, Klaas Vandepoele, Christian Sig Jensen, Tom Ruttink, Torben Asp   +7 more
doaj   +1 more source

Utility of Optical Genome Mapping in Repeat Disorders

Clinical Genetics
ABSTRACT Genomic repeat sequences are patterns of nucleic acids that exist in multiple copies throughout the genome. More than 60 Mendelian disorders are caused by the expansion or contraction of these repeats. Various specific methods for determining tandem repeat variations have been developed.
Mehmet Burak Mutlu, Taner Karakaya, Hamide Betül Gerik Çelebi, Fahrettin Duymuş, Serhat Seyhan, Sanem Yılmaz, Uluç Yiş, Tahir Atik, Mehmet Fatih Yetkin, Hakan Gümüş   +9 more
openaire   +6 more sources

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology
Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
doaj   +1 more source

Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping and assembly in Solanum species

MethodsX, 2018
Next-generation genome mapping through nanochannels (Bionano optical mapping) of plant genomes brings genome assemblies to the ‘nearly-finished’ level for reliable and detailed gene annotations and assessment of structural variations.
Paola Gaiero, Hana Šimková, Jan Vrána, Federico F. Santiñaque, Beatriz López-Carro, Gustavo A. Folle, José van de Belt, Sander A. Peters, Jaroslav Doležel, Hans de Jong   +9 more
doaj   +1 more source

Optical Genome Mapping Reveals Genomic Alterations upon Gene Editing in hiPSCs: Implications for Neural Tissue Differentiation and Brain Organoid Research

Cells
Genome editing, notably CRISPR (cluster regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9), has revolutionized genetic engineering allowing for precise targeted modifications.
Lucia Gallego Villarejo, Wanda M. Gerding, Lisa Bachmann, Luzie H. I. Hardt, Stefan Bormann, Huu Phuc Nguyen, Thorsten Müller   +6 more
doaj   +1 more source

Transcriptome and methylome profiling reveals relics of genome dominance in the mesopolyploid Brassica oleracea [PDF]

, 2014
Background: Brassica oleracea is a valuable vegetable species that has contributed to human health and nutrition for hundreds of years and comprises multiple distinct cultivar groups with diverse morphological and phytochemical attributes.
John Nixon, Denoeud, France, Parkin, Isobel AP, Annaliese S Mason, Town, Chris D, Huebert, Terry, Sharpe, Andrew G., Manoli, Sahana, Bancroft, Ian, France Denoeud, Sateesh Kagale, Just, J\ue9r\ue9my, Robinson, Stephen J., Vivek Krishnakumar, Clarke, Carling, Links, Matthew G., Robinson, Stephen J, Wayne E Clarke, Guy Barker, Barker, Guy C., Shelby L Bidwell, Koh, Chushin, Moore, Jonathan D., Sharpe, Andrew G, Jacqueline Batley, Edwards, David, Clarke, Wayne E., Harry Belcram, Jérémy Just, Bidwell, Shelby L., Just, Jérémy, Carling Clarke, Jonathan Moore, Edwards, Dave, Nelson, Matthew N, David Edwards, Batley, Jacqueline, Matthew N Nelson, Stephen J Robinson, Sahana Manoli, Bidwell, Shelby L, Pires, J. Chris, Parkin, Isobel A. P., Chalhoub, Boulos, Terry Huebert, Andrew H Paterson, Krishnakumar, Vivek, Belcram, Harry, H., Walley, Peter G, Bender, Tricia, Tricia Bender, Town, Chris D., Nelson, Matthew N., King, Graham, J Pires, Mason, Annaliese S., Graham King, Pires, Chris J., Matthew G Links, Nixon, John, Chris D Town, Boulos Chalhoub, Links, Matthew G, Ian Bancroft, Belcram, Harry, Walley, Peter G., Mason, Annaliese S, Paterson, Andrew H, Walley, Peter Glen, Paterson, Andrew H., Moore, Jonathan, Barker, Guy, Kagale, Sateesh, Wang, Xiyin, Tang, Haibao, Pires, J Chris, Isobel AP Parkin, Pires, J., Andrew G Sharpe, Clarke, Wayne E, Xiyin Wang, Haibao Tang, Peter G Walley, Chushin Koh   +83 more
core   +1 more source

Scanning the landscape of genome architecture of non-O1 and non-O139 Vibrio cholerae by whole genome mapping reveals extensive population genetic diversity. [PDF]

PLoS ONE, 2015
Historically, cholera outbreaks have been linked to V. cholerae O1 serogroup strains or its derivatives of the O37 and O139 serogroups. A genomic study on the 2010 Haiti cholera outbreak strains highlighted the putative role of non O1/non-O139 V ...
Carol Chapman, Matthew Henry, Kimberly A Bishop-Lilly, Joy Awosika, Adam Briska, Ryan N Ptashkin, Trevor Wagner, Chythanya Rajanna, Hsinyi Tsang, Shannon L Johnson, Vishwesh P Mokashi, Patrick S G Chain, Shanmuga Sozhamannan   +12 more
doaj   +1 more source

Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization [PDF]

, 2011
BACKGROUND The genomics era has produced an arsenal of resources from sequenced organisms allowing researchers to target species that do not have comparable mapping and sequence information.
Tuttle, Elaina M, Michael N Romanov, Jerry B Dodgson, Dodgson, Jerry B, Tuttle Elaina M, Elaina M Tuttle, Romanov, Michael N, Dodgson Jerry B, Romanov Michael N, Gonser Rusty A, Rusty A Gonser, Gonser, Rusty A   +11 more
core   +2 more sources

Genetic variation in the chicken genome: insights in selection [PDF]

, 2011
The chicken currently provides more than a quarter of the meat and nearly all eggs produced worldwide. For future improvements in production traits and animal welfare as well as to address future consumer demands it is necessary to understand the ...
Elferink, M.G.
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