Results 31 to 40 of about 4,090,293 (192)

Optical Genome Mapping: A New Tool for Cytogenomic Analysis. [PDF]

Genes (Basel)
Background/Objectives: Optical genome mapping (OGM) has recently emerged as a new technology in the clinical cytogenomics laboratories. This methodology has the ability to detect balanced and unbalanced structural rearrangements using ultra-high molecular weight DNA.
Levy B, Burnside RD, Akkari Y.
europepmc   +3 more sources

Structural Refinement by Direct Mapping Reveals Assembly Inconsistencies near Hi-C Junctions

Plants, 2023
High-throughput chromosome conformation capture (Hi-C) is widely used for scaffolding in de novo assembly because it produces highly contiguous genomes, but its indirect statistical approach can introduce connection errors.
Luca Marcolungo, Leonardo Vincenzi, Matteo Ballottari, Michela Cecchin, Emanuela Cosentino, Thomas Mignani, Antonina Limongi, Irene Ferraris, Matteo Orlandi, Marzia Rossato, Massimo Delledonne   +10 more
doaj   +1 more source

nanotatoR: a tool for enhanced annotation of genomic structural variants

BMC Genomics, 2021
Background Whole genome sequencing is effective at identification of small variants, but because it is based on short reads, assessment of structural variants (SVs) is limited. The advent of Optical Genome Mapping (OGM), which utilizes long fluorescently
Surajit Bhattacharya, Hayk Barseghyan, Emmanuèle C. Délot, Eric Vilain   +3 more
doaj   +1 more source

Billa Kalina [cartographic material] /

, 1948
Topographic map of Billa Kalina, South Australia. Relief shown by spot heights.; On verso: Mis.13079.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. National Mapping Section.
core   +3 more sources

Case Report: Optical genome mapping enables identification of complex balanced chromosomal rearrangements

Frontiers in Genetics
IntroductionIndividuals with balanced chromosomal rearrangements are at an increased risk for infertility, recurrent miscarriages, and the birth of infants with congenital malformations.
Xiaohang Hu, Jing Guo, Haiyang Sang, Jinyan Yan, Hong Chang, Ting Liu, Haixin Dong, Min Kong, Yanjun Tian, Liqing Jiang   +9 more
doaj   +1 more source

Broadband Backhaul Communication for Stratospheric Platforms: The Stratospheric Optical Payload Experiment (STROPEX) [PDF]

, 2006
A high bitrate optical downlink was performed by the stratospheric optical payload experiment (STROPEX), a part of the EU CAPANINA project. The STROPEX objectives were to design and build the necessary hardware to demonstrate an optical backhaul downlink
Knapek, Markus, Markus Knapek, Martin Brechtelsbauer, Joachim Horwath, Horwath, Joachim, Wilkerson, Brandon, Brandon Wilkerson, Brechtelsbauer, Martin, Bernhard Epple, Epple, Bernhard   +9 more
core   +1 more source

Large Chromosomal Rearrangements during a Long-Term Evolution Experiment with Escherichia coli

mBio, 2014
Large-scale rearrangements may be important in evolution because they can alter chromosome organization and gene expression in ways not possible through point mutations.
Colin Raeside, Joël Gaffé, Daniel E. Deatherage, Olivier Tenaillon, Adam M. Briska, Ryan N. Ptashkin, Stéphane Cruveiller, Claudine Médigue, Richard E. Lenski, Jeffrey E. Barrick, Dominique Schneider   +10 more
doaj   +1 more source

Analysis of Brachypodium genomes with genome-wide optical maps

Genome, 2018
Brachypodium distachyon (n = 5) is a diploid and has been widely used as a genetic model. Brachypodium stacei (n = 10) and B. hybridum (n = 15) are species that are related to B. distachyon, leading to an hypothesis that they are part of a polyploid series based on x = 5. Several lines of evidence suggest that this hypothesis is incorrect and that the
Zhu, Tingting, Hu, Zhaorong, Rodriguez, Juan C., Deal, Karin R., Dvorak, Jan, Vogel, John P, Liu, Zhiyong, Luo, Ming-Cheng   +7 more
openaire   +3 more sources

Is It Ordered Correctly? Validating Genome Assemblies by Optical Mapping [PDF]

The Plant Cell, 2017
Long-read single-molecule sequencing, Hi-C sequencing, and improved bioinformatic tools are ushering in an era where complete genome assembly will become common for species with few or no classical genetic resources. There are no guidelines for how to proceed in such cases.
Joshua A. Udall, R. Kelly Dawe
openaire   +2 more sources

Optical Genome Mapping ( OGM) : Looking beyond karyotyping

Asian Journal of Medical Sciences
Optical genome mapping (OGM) is an advanced technology that delivers a distinct view of genome structure. It presents numerous benefits compared to conventional sequencing techniques, as well as karyotyping in identifying large-scale structural ...
Ruby Dhar , Arun Kumar , Subhradip Karmakar   +2 more
doaj   +1 more source