Results 41 to 50 of about 4,290,469 (326)

Stellar Intensity Interferometry: Astrophysical targets for sub-milliarcsecond imaging [PDF]

open access: yes, 2010
Intensity interferometry permits very long optical baselines and the observation of sub-milliarcsecond structures. Using planned kilometric arrays of air Cherenkov telescopes at short wavelengths, intensity interferometry may increase the spatial ...
Dravins, Dainis   +3 more
core   +1 more source

Drug screening platform using human induced pluripotent stem cell‐derived atrial cardiomyocytes and optical mapping

open access: yesStem Cells Translational Medicine, 2020
Current drug development efforts for the treatment of atrial fibrillation are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac physiology and its response to medications. In this study, we demonstrated
Marvin G Gunawan   +7 more
semanticscholar   +1 more source

Optogenetic Control of Human Induced Pluripotent Stem Cell‐Derived Cardiac Tissue Models

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Optogenetics, using light‐sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high‐resolution optogenetic approaches to modulate electrical activity in 2‐ and 3‐dimensional ...
Amit Gruber   +8 more
doaj   +1 more source

Optical mapping of the 22q11.2DS region reveals complex repeat structures and preferred locations for non-allelic homologous recombination (NAHR)

open access: yesScientific Reports, 2020
The most prevalent microdeletion in humans occurs at 22q11.2, a region rich in chromosome-specific low copy repeats (LCR22s). The structure of this region has defied elucidation due to its size, regional complexity, and haplotype diversity, and is not ...
Steven Pastor   +20 more
semanticscholar   +1 more source

Examination of the Effects of Conduction Slowing on the Upstroke of Optically Recorded Action Potentials

open access: yesFrontiers in Physiology, 2019
IntroductionThe upstroke of optical action potentials (APs) recorded from intact hearts are generally recognized to be slower than those recorded with microelectrodes.
Christopher O’Shea   +4 more
doaj   +1 more source

Cross-correlation cosmography with HI intensity mapping [PDF]

open access: yes, 2015
The cross-correlation of a foreground density field with two different background convergence fields can be used to measure cosmographic distance ratios and constrain dark energy parameters.
Bacon, David   +2 more
core   +3 more sources

Optical Mapping-Validated Machine Learning Improves Atrial Fibrillation Driver Detection by Multi-Electrode Mapping

open access: yesCirculation: Arrhythmia and Electrophysiology, 2020
Supplemental Digital Content is available in the text. Background: Atrial fibrillation (AF) can be maintained by localized intramural reentrant drivers.
Alexander M. Zolotarev   +12 more
semanticscholar   +1 more source

Optical Mapping of Cardiac Electromechanics [PDF]

open access: yesBiophysical Journal, 2016
Cardiac biophysics rests on three fundamental pillars: energy production, electrical excitation, and mechanical work. Studies of cardiac metabolism, bioelectricity, and biomechanics have been very productive at all levels of reduced complexity, but especially at the levels of tissue, cell, and molecule.
Matthew W, Kay, Igor R, Efimov
openaire   +2 more sources

Simulating Photon Scattering Effects in Structurally Detailed Ventricular Models Using a Monte Carlo Approach

open access: yesFrontiers in Physiology, 2014
Light scattering during optical imaging of electrical activation within the heart is known to significantlydistort the optically-recorded action potential (AP) upstroke, as well as affecting the magnitude of the measured response of ventricular tissue to
Martin J Bishop, Gernot ePlank
doaj   +1 more source

Co-Registration of Optically Sensed Images and Correlation (COSI-Corr): an Operational Methodology for Ground Deformation Measurements [PDF]

open access: yes, 2008
Recent methodological progress, Co-Registration of Optically Sensed Images and Correlation, outlined here, makes it possible to measure horizontal ground deformation from optical images on an operational basis, using the COSI-Corr software package ...
Avouac, Jean-Philippe   +3 more
core   +1 more source

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