Results 41 to 50 of about 176,830 (290)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
OLS-Based RBF Neural Network for Nonlinear and Linear Impairments Compensation in the CO-OFDM System
IEEE Photonics Journal, 2018 For the first time, we propose and experimentally verify a novel low-complexity orthogonal least square (OLS) based radial basis function (RBF) neural network (NN) nonlinear equalizer for high-speed coherent optical orthogonal frequency division ...
Ling Liu +5 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Long-Range Distributed Vibration Sensing Based on Phase Extraction From Phase-Sensitive OTDR
IEEE Photonics Journal, 2016 Distributed fiber-optic vibration sensors based on phase-sensitive optical time-domain reflectometry ( $\phi$-OTDR) have found many applications in various fields.
Guangyao Yang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Single LED Beacon-Based 3-D Indoor Positioning Using Off-the-Shelf Devices
IEEE Photonics Journal, 2016 In this paper, we demonstrate a single light-emitting diode (LED) beacon-based 3-D indoor positioning scheme by experiment and theoretical derivation, which can overcome the limitation of multiple LED beacons involved in one positioning process. Only off-
Yinan Hou +5 more
doaj +1 more source
Optimization of the Non-Linearity Tolerant 4D Geometric Shaped Constellations for Optical Fiber Communication Systems Using Neural Networks [PDF]
, 2023 Amirhosein Soleimanzade +2 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
IEEE Photonics Journal, 2017 In this paper, the performance of polar code in high-speed coherent optical orthogonal frequency division multiplexing (CO-OFDM) system with nonlinear and linear impairments is comprehensively investigated for the first time.
Ling Liu +5 more
doaj +1 more source