Results 51 to 60 of about 579,349 (293)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nonlinear quantum optical computing via measurement [PDF]

open access: yes, 2004
We show how the measurement induced model of quantum computation proposed by Raussendorf and Briegel [Phys. Rev. Letts. 86, 5188 (2001)] can be adapted to a nonlinear optical interaction. This optical implementation requires a Kerr nonlinearity, a single
Hutchinson, G. D., Milburn, G. J.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Impact and Compensation of Electrical-to-Optical Frequency Response on Carrierless Phase Retrieval Receivers

open access: yesIEEE Photonics Journal
On carrierless phase retrieval (PR) receivers based on direct detection, bandwidth limitation of electrical-to-optical (E/O) conversion at the transmitter side (Tx) distorts the modulated optical signal.
Qi Gao   +5 more
doaj   +1 more source

Metamaterial-enabled arbitrary on-chip spatial mode manipulation

open access: yesLight: Science & Applications, 2022
On-chip spatial mode operation, represented as mode-division multiplexing (MDM), can support high-capacity data communications and promise superior performance in various systems and numerous applications from optical sensing to nonlinear and quantum ...
Jinlong Xiang   +6 more
doaj   +1 more source

Ultrafast all-optical signal processing how and why? [PDF]

open access: yes, 2010
Demand for fast and secure high capacity networks is growing. Currently offered solutions are hampered by the reappearance of electronic bottleneck. It is believed that to fully utilize transmission bandwidth of optical networks ultrafast all-optical ...
Glesk, Ivan
core  

Modelling of all-optical symmetric Mach-Zehnder switch with asymmetric coupler [PDF]

open access: yes, 2009
Ultra high-speed optical network is developing rapidly as growing capacity demand in telecommunication system is increasing. In these networks, it is desired to carry out switching, routing and processing in optical domain to avoid bottlenecks of ...
Ghassemlooy, Zabih   +3 more
core   +1 more source

Optical Axons for Electro-Optical Neural Networks [PDF]

open access: yesSensors, 2020
Recently, neuromorphic sensors, which convert analogue signals to spiking frequencies, have been reported for neurorobotics. In bio-inspired systems these sensors are connected to the main neural unit to perform post-processing of the sensor data. The performance of spiking neural networks has been improved using optical synapses, which offer parallel ...
Mircea Hulea   +4 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Operating penalties in single-fiber operation 10-Gb/s, 1024-way split, 110-km long-reach optical access networks [PDF]

open access: yes, 2006
We report for the first time optical signal-to-noise penalties which lead to performance degradations in single-fiber long-reach optical access networks when compared to identical dual-fiber systems.
Mitchell, J.E., Shea, D.P.
core   +1 more source

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