Results 41 to 50 of about 59,475 (266)

Integrated optical dipole trap for cold neutral atoms with an optical waveguide coupler

open access: yesNew Journal of Physics, 2013
An integrated optical dipole trap uses two-color (red and blue-detuned) traveling evanescent wave fields for trapping cold neutral atoms. To achieve longitudinal confinement, we propose using an integrated optical waveguide coupler, which provides a ...
J Lee   +4 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Obtaining an Optical Trap Type Surface by Plasma Electrolytic Oxidation [PDF]

open access: yesMaterials Research, 2018
High performance solar collectors are those with high selectivity surfaces, high solar radiation absorption and that do not thermally reemit to the external environment.
Hugo Fernandes Medeiros da Silva   +5 more
doaj   +1 more source

The trapping and detection of single atoms using a spherical mirror

open access: yesNew Journal of Physics, 2012
We fabricate a miniature spherical mirror for tightly focusing an optical dipole trap for neutral atoms. The mirror formation process is modelled to predict the dimensions for particular fabrication parameters.
Arpan Roy   +2 more
doaj   +1 more source

Particle Manipulation by Optical Forces in Microfluidic Devices

open access: yesMicromachines, 2018
Since the pioneering work of Ashkin and coworkers, back in 1970, optical manipulation gained an increasing interest among the scientific community. Indeed, the advantages and the possibilities of this technique are unsubtle, allowing for the manipulation
Petra Paiè   +4 more
doaj   +1 more source

Microrheology With an Anisotropic Optical Trap

open access: yesFrontiers in Physics, 2021
Microrheology with optical tweezers (MOT) measurements are usually performed using optical traps that are close to isotropic across the plane being imaged, but little is known about what happens when this is not the case. In this work, we investigate the
Andrew B. Matheson   +6 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Optical trapping and optical binding using cylindrical vector beams

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2011
We report on the use of cylindrical vector beams for optical manipulation of micron and sub-micron sized particles using the methods of a single-beam gradient force trap (optical tweezers) and an evanescent-field surface trap (optical binding).
S. E. Skelton   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Bidirectional helical motility of cytoplasmic dynein around microtubules

open access: yeseLife, 2014
Cytoplasmic dynein is a molecular motor responsible for minus-end-directed cargo transport along microtubules (MTs). Dynein motility has previously been studied on surface-immobilized MTs in vitro, which constrains the motors to move in two dimensions ...
Sinan Can, Mark A Dewitt, Ahmet Yildiz
doaj   +1 more source

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