Results 81 to 90 of about 12,294,384 (368)

Abnormality in the Theory of Necessary Optimality Conditions

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2017
The problems of existence, non-uniqueness, abnormality of solutions arising from the using of necessary optimality conditions are discussed in terms of the extension principle and sufficient optimality conditions. Simple examples are used.
V.I. Gurman, M.M. Khrustalev
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A Minimax-Program-Based Approach for Robust Fractional Multi-Objective Optimization

open access: yesMathematics
In this paper, by making use of some advanced tools from variational analysis and generalized differentiation, we establish necessary optimality conditions for a class of robust fractional minimax programming problems.
Henan Li, Zhe Hong, Do Sang Kim
doaj   +1 more source

Optimality Conditions for Nondifferentiable Multiobjective Semi-Infinite Programming Problems

open access: yesAbstract and Applied Analysis, 2016
We have considered a multiobjective semi-infinite programming problem with a feasible set defined by inequality constraints. First we studied a Fritz-John type necessary condition. Then, we introduced two constraint qualifications and derive the weak and
D. Barilla, G. Caristi, A. Puglisi
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Optimality conditions associated with new controlled extremization models

open access: yesAIMS Mathematics
Applying a parametric approach, in this paper we studied a new class of multidimensional extremization models with data uncertainty. Concretely, first, we derived the robust conditions of necessary optimality. Thereafter, we established robust sufficient
Tareq Saeed
doaj   +1 more source

Topological optimization and inverse problems

open access: yesComputer Assisted Methods in Engineering and Science, 2023
The topological derivative of an arbitrary shape functional is introduced in [29] for 2D elasticity. The optimality conditions for general shape optimization problems are established in [30] using the shape variations including boundary and topology ...
Lidia Jackowska-Strumiłło   +2 more
doaj  

Hodges-Lehmann Optimality for Testing Moment [PDF]

open access: yes
This paper studies the Hodges and Lehmann (1956) optimality of tests in a general setup. The tests are compared by the exponential rates of growth to one of the power functions evaluated at a fixed alternative while keeping the asymptotic sizes bounded ...
Ivan Canay, Taisuke Otsu
core  

Determination of the Optimal Operative Conditions for the Torrefaction of Olive Waste Biomass [PDF]

open access: gold, 2020
Jaime Martín-Pascual   +3 more
openalex   +1 more source

Home - About - Disclaimer - Privacy