Abnormality in the Theory of Necessary Optimality Conditions
The problems of existence, non-uniqueness, abnormality of solutions arising from the using of necessary optimality conditions are discussed in terms of the extension principle and sufficient optimality conditions. Simple examples are used.
V.I. Gurman, M.M. Khrustalev
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
A Minimax-Program-Based Approach for Robust Fractional Multi-Objective Optimization
In this paper, by making use of some advanced tools from variational analysis and generalized differentiation, we establish necessary optimality conditions for a class of robust fractional minimax programming problems.
Henan Li, Zhe Hong, Do Sang Kim
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Optimality Conditions for Nondifferentiable Multiobjective Semi-Infinite Programming Problems
We have considered a multiobjective semi-infinite programming problem with a feasible set defined by inequality constraints. First we studied a Fritz-John type necessary condition. Then, we introduced two constraint qualifications and derive the weak and
D. Barilla, G. Caristi, A. Puglisi
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Optimality conditions associated with new controlled extremization models
Applying a parametric approach, in this paper we studied a new class of multidimensional extremization models with data uncertainty. Concretely, first, we derived the robust conditions of necessary optimality. Thereafter, we established robust sufficient
Tareq Saeed
doaj +1 more source
Topological optimization and inverse problems
The topological derivative of an arbitrary shape functional is introduced in [29] for 2D elasticity. The optimality conditions for general shape optimization problems are established in [30] using the shape variations including boundary and topology ...
Lidia Jackowska-Strumiłło +2 more
doaj
Field- and concentration-dependent relaxation of magnetic nanoparticles and optimality conditions for magnetic fluid hyperthermia. [PDF]
Ilg P, Kröger M.
europepmc +1 more source
Hodges-Lehmann Optimality for Testing Moment [PDF]
This paper studies the Hodges and Lehmann (1956) optimality of tests in a general setup. The tests are compared by the exponential rates of growth to one of the power functions evaluated at a fixed alternative while keeping the asymptotic sizes bounded ...
Ivan Canay, Taisuke Otsu
core
Determination of the Optimal Operative Conditions for the Torrefaction of Olive Waste Biomass [PDF]
Jaime Martín-Pascual +3 more
openalex +1 more source

