Results 31 to 40 of about 676,204 (267)

ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas

open access: yesPharmaceutics, 2019
Drug delivery into the brain is regulated by the blood−brain interfaces. The blood−brain barrier (BBB), the blood−cerebrospinal fluid barrier (BCSFB), and the blood−arachnoid barrier (BAB) regulate the exchange of substances ...
David Gomez-Zepeda   +4 more
doaj   +1 more source

A Systematic Literature Review on Fake News in the COVID-19 Pandemic: Can AI Propose a Solution?

open access: yesApplied Sciences, 2022
The COVID-19 pandemic has led to an incredible amount of fake news and conspiracy theories around the world. Calls for the integration of COVID-19 and fake news-related research have been advanced in various fields. This paper aims to unpack a structured
Tanvir Ahmad   +2 more
doaj   +1 more source

Patient and public involvement in designing and conducting doctoral research: the whys and the hows

open access: yesResearch Involvement and Engagement, 2019
Plain English summary Evidence shows that public and patient involvement in research has a positive effect on its quality and end-results. Thus, public and patient involvement in all stages of research is becoming commonplace.
Justine Tomlinson   +4 more
doaj   +1 more source

Pharmacophore-Based Discovery of Substrates of a Novel Drug/Proton-Antiporter in the Human Brain Endothelial hCMEC/D3 Cell Line

open access: yesPharmaceutics, 2022
A drug/proton-antiporter, whose the molecular structure is still unknown, was previously evidenced at the blood-brain barrier (BBB) by functional experiments. The computational method could help in the identification of substrates of this solute carrier (
Maria Smirnova   +6 more
doaj   +1 more source

Numerical modeling of shape and topology optimisation of a piezoelectric cantilever beam in an energy-harvesting sensor [PDF]

open access: yes, 2016
Piezoelectric materials are excellent transducers for converting mechanical energy from the environment for use as electrical energy. The conversion of mechanical energy to electrical energy is a key component in the development of self-powered devices ...
Liu, Jing-Sheng, Thein, Chung Ket
core   +1 more source

Optimising Optimisers with Push GP [PDF]

open access: yes, 2020
This work uses Push GP to automatically design both local and population-based optimisers for continuous-valued problems. The optimisers are trained on a single function optimisation landscape, using random transformations to discourage overfitting.
openaire   +2 more sources

A Study on Phase-Changing Materials for Controllable Stiffness in Robotic Joints

open access: yesRobotics, 2022
This paper studies the viability of using a class of phase-changing materials for the design of controlled variable stiffness robotic joints which enable the design of robots that can operate in confined spaces.
Bingyin Ma   +3 more
doaj   +1 more source

Enhancement of speed and efficiency of an Internet based gear design optimisation [PDF]

open access: yes, 2003
An internet-based gear design optimisation program has been developed for geographically dispersed teams to collaborate over the internet. The optimisation program implements genetic algorithm.
Amin, N, Su, D
core   +1 more source

Supporting medicines management for older people at care transitions – a theory-based analysis of a systematic review of 24 interventions

open access: yesBMC Health Services Research, 2021
Background Older patients are at severe risk of harm from medicines following a hospital to home transition. Interventions aiming to support successful care transitions by improving medicines management have been implemented.
Justine Tomlinson   +4 more
doaj   +1 more source

General practitioner practice-based pharmacist input to medicines optimisation in the UK: pragmatic, multicenter, randomised, controlled trial

open access: yesJournal of Pharmaceutical Policy and Practice, 2021
Background Changing demographics across the UK has led to general practitioners (GPs) managing increasing numbers of older patients with multi-morbidity and resultant polypharmacy. Through government led initiatives within the National Health Service, an
Nadia Farhanah Syafhan   +14 more
doaj   +1 more source

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