Results 61 to 70 of about 10,104,704 (372)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Registration of dermatoscopic images of skin neoplasms and detection of structural differences
Системный анализ и прикладная информатика, 2023 The paper considers the application of an algorithm based on a morphological projector for determining structural differences for comparing dermoscopic images.
A. F. Smalyuk +2 more
doaj +1 more source
Optimal Distributed Covering Algorithms [PDF]
Proceedings of the 2019 ACM Symposium on Principles of Distributed Computing, 2019 AbstractWe present a time-optimal deterministic distributed algorithm for approximating a minimum weight vertex cover in hypergraphs of rank f. This problem is equivalent to the Minimum Weight Set Cover problem in which the frequency of every element is bounded by f. The approximation factor of our algorithm is $$(f+\varepsilon )$$
Ben-Basat, Ran +3 more
openaire +7 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Stochastic Block Mirror Descent Methods for Nonsmooth and Stochastic Optimization [PDF]
, 2013 In this paper, we present a new stochastic algorithm, namely the stochastic block mirror descent (SBMD) method for solving large-scale nonsmooth and stochastic optimization problems. The basic idea of this algorithm is to incorporate the block-coordinate
Dang, Cong D., Lan, Guanghui
core
Golden Search Optimization Algorithm
IEEE Access, 2022 This study introduces an effective population-based optimization algorithm, namely the Golden Search Optimization Algorithm (GSO), for numerical function optimization.
Mohammad Noroozi +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
HeliyonThis paper proposes Pomarine jaeger Optimization (PJO) algorithm, Tiger hunting Optimization (THO) Algorithm, Desert Reynard and Vixen Inspired Optimization (DRVIO) Algorithm, Lonchodidae optimization (LO) algorithm, Caracal optimization (CO) algorithm ...
Lenin Kanagasabai
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A Brief Comparison of Particle Swarm Optimization Algorithm and Firefly Algorithm
Jurnal informatika UPGRIS, 2018 In this article, we try to present some optimization algorithms that are often used by researchers. Through the information contained in this article, the reader can know and understand the development and mechanism of optimization algorithms.
Ahmad Sanmorino
doaj +1 more source