Results 61 to 70 of about 4,446,877 (297)

Change of ant fauna in the Gwangneung forest: Test on influence of climatic warming

open access: yesJournal of Asia-Pacific Biodiversity, 2014
Based on data of ants that were surveyed by the same method in the Gwangneung forest in 1993 and 2009, influences of climate changes on ant fauna were examined.
Tae-Sung Kwon
doaj   +1 more source

Optimum high temperature strength of two-dimensional nanocomposites

open access: yesAPL Materials, 2013
High-temperature nanoindentation was used to reveal nano-layer size effects on the hardness of two-dimensional metallic nanocomposites. We report the existence of a critical layer thickness at which strength achieves optimal thermal stability ...
M. A. Monclús   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Impact of Temperature on Podding in Faba Bean (Vicia faba)

open access: yesAgronomy
Faba bean is grown globally for human consumption and animal feed and is a significant rotation crop in cereal-dominant areas in many countries, including Australia.
Bill K. Manning   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Optimum reaction conditions for the synthesis of macromonomers via the high-temperature polymerization of acrylates

open access: yes, 2009
Macromonomers are valuable synthetic building blocks: They can be copolymerized with low molecular weight monomers to generate brush-like structures or serve as conjugation substrates in pericylic, metathesis, and thiolene reactions.
Thomas Junkers   +3 more
core   +1 more source

Evaluate the Climate Calendar of Beekeepers in West Azerbaijan Province Based on Thermal Conditions

open access: yesتحقيقات جغرافيايی, 2016
Study the atmospheric elements and identify thermal conditions affecting beekeepers is of particular importance. In this research, given the importance of high temperature and beekeeping activities, the daily maximum and minimum temperatures were used in
Gholamabbas Fallah Ghalhari   +2 more
doaj  

Response of Maize (Zea mays L.) to a Temperature Gradient Representing Long-Term Climate Change Under Different Soil Management Systems

open access: yesTropical Agricultural Research, 2015
Maize (Zea mays L.) yields in Sri Lanka have been below its potential yield mainly due to biotic and abiotic stresses. This situation is likely to be aggravated in a changing climate in the future.
M.A.P.W.K. Malaviarachchi   +5 more
doaj   +1 more source

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