Results 71 to 80 of about 4,446,877 (297)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Optimization of Culture Conditions for Growth of Marine Phytoplankton

open access: yesJournal of Tropical Life Science, 2020
The present study investigated the optimum levels of ambient temperature, salinity and light intensity for the growth of marine diatoms and microalgae. The marine diatoms Thalassiosira subtilis, Entomoneis paludosa and microalgae Isochrysis galbana were ...
Kunguma Kannika Maharajan   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

An Optimum-Currency-Area Odyssey [PDF]

open access: yes
The theory of optimum-currency-areas was conceived and developed in three highly influential papers, written by Mundell (1961), McKinnon (1963) and Kenen (1969).
Harris Dellas, George S.Tavlas
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

The Optimum Growth Rate for Population Reconsidered [PDF]

open access: yes
This article gives exact general conditions for the existence of an interior optimum growth rate for population in the neoclassical two-generations-overlapping model.
Klaus Jaeger, Wolfgang Kuhle
core  

Non-optimum temperature increases risk and burden of acute myocardial infarction onset: A nationwide case-crossover study at hourly level in 324 Chinese cities. [PDF]

open access: yesEClinicalMedicine, 2022
Jiang Y   +21 more
europepmc   +1 more source

Selected, optimum, pessimal and tolerant temperatures in cladocera Simocephalus vetulus (O.F. Müller, 1776)

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2015
Temperature election and avoidance are investigated in Simocephalus vetulus (O.F. Müller 1776), caught during the vegetative season in the littoral of the Rybinsk Reservoir.
doaj   +1 more source

Experimental investigation of coupled thermo-mechanical behaviour of Kaolin clay [PDF]

open access: yesE3S Web of Conferences
An experimental study regarding the thermo-mechanical behaviour of a Malaysian Kaolin is presented in this paper. Mercury intrusion porosimetry (MIP) tests have been performed on compacted samples with varying initial water contents. Samples compacted at
Kayser Timon   +3 more
doaj   +1 more source

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