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Background: Optogenetic stimulation has grown into a popular brain stimulation method in basic neuroscience while electrical stimulation predominates in clinical applications.
Theresa CS. Weidner +7 more
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Platforms for Optogenetic Stimulation and Feedback Control
Harnessing the potential of optogenetics in biology requires methodologies from different disciplines ranging from biology, to mechatronics engineering, to control engineering.
Sant Kumar, Mustafa Khammash
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Combined-electrical optogenetic stimulation but not channelrhodopsin kinetics improves the fidelity of high rate stimulation in the auditory pathway in mice [PDF]
Novel stimulation methods are needed to overcome the limitations of contemporary cochlear implants. Optogenetics is a technique that confers light sensitivity to neurons via the genetic introduction of light-sensitive ion channels.
Elise A. Ajay +6 more
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High optical power of optogenetic stimulation may cause phototoxicity during chronic application. To lower the optical power, a hybrid approach which combines optogenetic and electric modalities has been proposed.
Hyeonhee Roh +3 more
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Optogenetic stimulation of cell bodies versus axonal terminals generate comparable activity and functional connectivity patterns in the brain [PDF]
Optogenetic techniques are often employed to dissect neural pathways with presumed specificity for targeted projections. In this study, we used optogenetic fMRI to investigate the effective landscape of stimulating the cell bodies versus one of its ...
Li-Ming Hsu +3 more
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Modeling the modulation of beta oscillations in the basal ganglia by dual-target optogenetic stimulation [PDF]
Optogenetic techniques provide precise control over the activity of specific neurons within the nucleus, offering more accurate regulatory effects compared to deep brain stimulation.
Xiaomin Wang, Ying Yu, Qingyun Wang
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Optogenetic mapping of feeding and self-stimulation within the lateral hypothalamus of the rat. [PDF]
The lateral hypothalamus (LH) includes several anatomical subregions involved in eating and reward motivation. This study explored localization of function across different LH subregions in controlling food intake stimulated by optogenetic ...
Kevin R Urstadt, Kent C Berridge
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Optogenetic stimulation of inferior colliculus neurons elicits mesencephalic locomotor region activity and reverses haloperidol-induced catalepsy in rats [PDF]
The inferior colliculus (IC) represents a pivotal midbrain area involved in processing sensory/emotional facets of auditory stimuli, potentially influencing motor responses.
José A. Pochapski +7 more
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Optogenetic stimulation of the peripheral nervous system is a novel approach to motor control, somatosensory transduction, and pain processing. Various optical stimulation tools have been developed for optogenetic stimulation using optical fibers and ...
Kang-Il Song +5 more
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Cochlear implants (CIs) restore activity in the deafened auditory system via electrical stimulation of the auditory nerve. As the spread of electric current in biological tissues is rather broad, the spectral information provided by electrical CIs is ...
Maria Michael +5 more
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