Results 21 to 30 of about 704,312 (278)

Optogenetic stimulation of neuronal repair [PDF]

Current Biology, 2015
Environmental insult, disease or trauma can affect the physical integrity of neuronal circuits, and the inability of many neurons to regenerate injured axons invariably leads to irreversible neural dysfunction. The conserved second messenger cyclic adenosine monophosphate (cAMP) can promote axonal re-growth.
Xiao, Y., Tian, W., López-Schier, H.
openaire   +3 more sources

Optogenetic stimulation of the cochlea [PDF]

, 2022
Optogenetic stimulation of the auditory nerve is a promising alternative to restore hearing. Since light can be focused on the target tissue, the optical cochlear implant (oCI) might support a major improvement in frequency resolution compared to current electrical CIs (eCIs).
López de la Morena, David, Moser, Tobias, Georg-August-Universität Göttingen, Rizzoli, Silvio O., Gollisch, Tim, Strenzke, Nicola, Dean, Camin, Schmidt, Manuela   +7 more
openaire   +2 more sources

Differential optogenetic activation of the auditory midbrain in freely moving behaving mice

Frontiers in Systems Neuroscience, 2023
IntroductionIn patients with severe auditory impairment, partial hearing restoration can be achieved by sensory prostheses for the electrical stimulation of the central nervous system.
Meike M. Rogalla, Meike M. Rogalla, Adina Seibert, Jana M. Sleeboom, K. Jannis Hildebrandt, K. Jannis Hildebrandt   +5 more
doaj   +1 more source

Optogenetic stimulation of the auditory pathway [PDF]

Journal of Clinical Investigation, 2014
Auditory prostheses can partially restore speech comprehension when hearing fails. Sound coding with current prostheses is based on electrical stimulation of auditory neurons and has limited frequency resolution due to broad current spread within the cochlea.
Hernandez, V.H., Gehrt, A., Reuter, K., Jing, Z., Jeschke, M., Schulz, A.M., Hoch, G., Bartels, M., Vogt, G., Garnham, C.W., Yawo, H., Fukazawa, Y., Augustine, G.J., Bamberg, E., Kügler, S., Salditt, T., De Hoz, L., Strenzke, N., Moser, T.   +18 more
openaire   +5 more sources

Optogenetic stimulation

, 2023
Containing optogenetic stimulation experiments data related to Figure 6 and 7.
Falkner Lab (17476770)
core   +1 more source

High spatial resolution artificial vision inferred from the spiking output of retinal ganglion cells stimulated by optogenetic and electrical means

Frontiers in Cellular Neuroscience, 2022
With vision impairment affecting millions of people world-wide, various strategies aiming at vision restoration are being undertaken. Thanks to decades of extensive research, electrical stimulation approaches to vision restoration began to undergo ...
Andreea Elena Cojocaru, Andrea Corna, Miriam Reh, Günther Zeck   +3 more
doaj   +1 more source

Properties of an optogenetic model for olfactory stimulation [PDF]

The Journal of Physiology, 2016
Key points In olfactory research it is difficult to deliver stimuli with defined intensity and duration to olfactory sensory neurons. Expression of channelrhodopsin 2 (ChR2) in olfactory sensory neurons provides a means to activate these neurons with light flashes. Appropriate mouse models are available. The present study explores the suitability of an
Federica, Genovese, Marion, Thews, Frank, Möhrlen, Stephan, Frings   +3 more
openaire   +2 more sources

Optogenetic activation of visual thalamus generates artificial visual percepts

eLife, 2023
The lateral geniculate nucleus (LGN), a retinotopic relay center where visual inputs from the retina are processed and relayed to the visual cortex, has been proposed as a potential target for artificial vision.
Jing Wang, Hamid Azimi, Yilei Zhao, Melanie Kaeser, Pilar Vaca Sánchez, Abraham Vazquez-Guardado, John A Rogers, Michael Harvey, Gregor Rainer   +8 more
doaj   +1 more source

Optogenetic stimulation of the dorsal striatum bidirectionally controls seizures. [PDF]

Proc Natl Acad Sci U S A
Abstract Engagement of the striatum (caudate/putamen) and other basal ganglia nuclei during seizures was first observed over 75 years ago. Basal ganglia output nuclei, and the substantia nigra pars reticulata, in particular, have well-established anti-seizure effects across a large array of experimental models. However, striatal control
Hyder SK, Lazarini-Lopes W, Toib J, Williams G, Sukharev A, Forcelli PA.   +5 more
europepmc   +5 more sources

Perceptual Weighting of Mouse V1 Spikes Revealed by Optogenetic White Noise Stimulation [PDF]

, 2021
After photons enter the eye, neurons transduce them into patterns of spikes that propagate through the brain until we visually perceive them. We and other animals do this quickly and reliably, but the specific qualities of the spike trains that lead to ...
Day-Cooney, Julian
core   +1 more source