Optogenetics: Background, Methodological Advances and Potential Applications for Cardiovascular Research and Medicine [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Optogenetics is an elegant approach of precisely controlling and monitoring the biological functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution by using optical system and genetic engineering technologies. The
Jyotsna Joshi +2 more
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The Roles of Optogenetics and Technology in Neurobiology: A Review
Frontiers in Aging Neuroscience, 2022 Optogenetic is a technique that combines optics and genetics to control specific neurons. This technique usually uses adenoviruses that encode photosensitive protein. The adenovirus may concentrate in a specific neural region.
Wenqing Chen +13 more
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Applications and challenges of rhodopsin-based optogenetics in biomedicine
Frontiers in Neuroscience, 2022 Optogenetics is an emerging bioengineering technology that has been rapidly developed in recent years by cross-integrating optics, genetic engineering, electrophysiology, software control, and other disciplines.
Hanci Zhang +9 more
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Optogenetics: implications for Alzheimer’s disease research and therapy
Molecular Brain, 2022 Alzheimer’s disease (AD), a critical neurodegenerative condition, has a wide range of effects on brain activity. Synaptic plasticity and neuronal circuits are the most vulnerable in Alzheimer’s disease, but the exact mechanism is unknown.
Parsa Mirzayi +4 more
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High fidelity optogenetic control of individual prefrontal cortical pyramidal neurons in vivo [PDF]
, 2012 Precise spatial and temporal manipulation of neural activity in specific genetically defined cell populations is now possible with the advent of optogenetics.
Shinya Nakamura +4 more
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Optogenetics and chemogenetics: key tools for modulating neural circuits in rodent models of depression [PDF]
Frontiers in Neural CircuitsOptogenetics and chemogenetics are emerging neuromodulation techniques that have attracted significant attention in recent years. These techniques enable the precise control of specific neuronal types and neural circuits, allowing researchers to ...
Shaowei Li +5 more
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Ultrasound-Triggered In Situ Photon Emission for Noninvasive Optogenetics.
Journal of the American Chemical Society, 2023 Optogenetics has revolutionized neuroscience understanding by allowing spatiotemporal control over cell-type specific neurons in neural circuits. However, the sluggish development of noninvasive photon delivery in the brain has limited the clinical ...
Wenliang Wang +9 more
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Frontiers in Psychology, 2022 In recent years, the utility and efficiency of automated procedures for cognitive assessment in psychology and neuroscience have been demonstrated in non-human primates (NHP).
Jorge Cabrera-Moreno +13 more
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Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters
Cell Discovery, 2023 Naturally occurring fluorescent proteins (FPs) are the most widely used tools for tracking cellular proteins and sensing cellular events. Here, we chemically evolved the self-labeling SNAP-tag into a palette of SNAP-tag mimics of fluorescent proteins ...
Dasheng Zhang +20 more
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Optophysiology: Illuminating cell physiology with optogenetics
Physiological Reviews, 2022 Optogenetics combines light and genetics to enable precise control of living cells, tissues, and organisms with tailored functions. Optogenetics has the advantages of noninvasiveness, rapid responsiveness, tunable reversibility, and superior ...
Peng Tan, Lian He, Yun Huang, Yubin Zhou
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