Results 11 to 20 of about 20,290 (227)
Nature Communications, 2021 Pulsing cellular dynamics in genetic circuits have been shown to provide critical capabilities to cells in stress response, signaling and development.
Ting Li +9 more
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Emerging optogenetics technologies in biomedical applications
Smart Medicine, 2023 Optogenetics is a cutting‐edge technology that merges light control and genetics to achieve targeted control of tissue cells. Compared to traditional methods, optogenetics offers several advantages in terms of time and space precision, accuracy, and ...
Haozhen Ren +4 more
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Frontiers in Psychiatry, 2022 BackgroundsThe neural circuit mechanisms underlying depression remain unclear. Recently optogenetics has gradually gained recognition as a novel technique to regulate the activity of neurons with light stimulation.
Shanshan Lin +11 more
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Nature Communications, 2023 Optogenetics tools for precise temporal and spatial control of protein abundance are valuable in studying diverse complex biological processes. In the present study, we engineer a monomeric tag of stabilization upon light induction (SULI) for yeast and ...
Miaowei Mao +6 more
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Optogenetics in primate cortical networks
Frontiers in Neuroanatomy, 2023 The implementation of optogenetics in studies on non-human primates has generally proven quite difficult, but recent successes have paved the way for its rapid increase.
Sam Merlin +2 more
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X-Optogenetics and U-Optogenetics: Feasibility and Possibilities
Photonics, 2015 Optogenetics is an established technique that uses visible light to modulate membrane voltage in neural cells. Although optogenetics allows researchers to study parts of the brain like never before, it is limited because it is invasive, and visible light
Rachel Berry +3 more
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Step Sequence is a Critical Gait Parameter of Unilateral 6-OHDA Parkinson's Rat Models
Cell Transplantation, 2017 Parkinson's disease is a progressive neurological disorder, marked by the loss of dopaminergic neurons in the nigrostriatal pathway that leads to abnormal gait, rigidity, slowness of movement, and tremor.
Heather A. Baldwin +4 more
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The Roles of Optogenetics and Technology in Neurobiology: A Review
Frontiers in Aging Neuroscience, 2022 Optogenetic is a technique that combines optics and genetics to control specific neurons. This technique usually uses adenoviruses that encode photosensitive protein. The adenovirus may concentrate in a specific neural region.
Wenqing Chen +13 more
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Rods progressively escape saturation to drive visual responses in daylight conditions
Nature Communications, 2017 Rod photoreceptors are thought to be saturated under bright light. Here, the authors describe the physiological parameters that mediate response saturation of rod photoreceptors in mouse retina, and show that rods can drive visual responses in photopic ...
Alexandra Tikidji-Hamburyan +14 more
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Photonics, 2019 Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this purpose since it allows us to study the functionality of neuronal ...
Elena Montagni +3 more
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