Results 11 to 20 of about 43,018 (315)

A bibliometric profile of optogenetics: quantitative and qualitative analyses

Frontiers in Neuroscience, 2023
IntroductionOptogenetics is a rapidly developing field combining optics and genetics, with promising applications in neuroscience and beyond.
Zhonghan Zhou, Zhonghan Zhou, Zhonghan Zhou, Zhonghan Zhou, Zhonghan Zhou, Xuesheng Wang, Xuesheng Wang, Xuesheng Wang, Xuesheng Wang, Xuesheng Wang, Xunhua Li, Xunhua Li, Xunhua Li, Xunhua Li, Xunhua Li, Limin Liao, Limin Liao, Limin Liao, Limin Liao, Limin Liao, Limin Liao   +20 more
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Optogenetics 3.0 [PDF]

Cell, 2010
Optogenetic methods use light to modulate the activities of target cells in vivo. By improving inter- and intracellular trafficking of light-sensitive switch proteins called opsins, Gradinaru et al. (2010) have developed a new generation of optogenetic tools capable of regulating the activity of targeted neurons with exquisite precision and efficiency.
Liu, Xu, Tonegawa, Susumu
openaire   +3 more sources

Optogenetics: Solving the Enigma of Sleep [PDF]

Sleep Medicine Research, 2018
Sleep is a crucial and evolutionarily conserved phenomenon, but the mechanisms that control sleep-wake behavior and underlie sleep disorders are not yet fully understood.
Victor James Drew, Jae Meen Lee, Tae Kim
doaj   +1 more source

Tools for Controlling Activity of Neural Circuits Can Boost Gastrointestinal Research [PDF]

, 2016
We thank Prof U. G. Knaus and T. C. Collin for critical reading of the manuscript. GA is supported by the European Crohn's and Colitis Organization (ECCO) (J/15/2) and by the National Childrens' Research Centre (K/12/1). GD is supported by the University
Aviello, Gabriella, D'Agostino, Giuseppe
core   +6 more sources

Advances in optogenetic studies of depressive-like behaviors and underlying neural circuit mechanisms

Frontiers in Psychiatry, 2022
BackgroundsThe neural circuit mechanisms underlying depression remain unclear. Recently optogenetics has gradually gained recognition as a novel technique to regulate the activity of neurons with light stimulation.
Shanshan Lin, Shanshan Lin, Yiwei Du, Yiwei Du, Yujie Xia, Yujie Xia, Yumeng Xie, Yumeng Xie, Ling Xiao, Ling Xiao, Gaohua Wang, Gaohua Wang   +11 more
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Emerging optogenetics technologies in biomedical applications

Smart Medicine, 2023
Optogenetics is a cutting‐edge technology that merges light control and genetics to achieve targeted control of tissue cells. Compared to traditional methods, optogenetics offers several advantages in terms of time and space precision, accuracy, and ...
Haozhen Ren, Yi Cheng, Gaolin Wen, Jinglin Wang, Min Zhou   +4 more
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Bimodal activation of different neuron classes with the spectrally red-shifted channelrhodopsin chimera C1V1 in Caenorhabditis elegans [PDF]

, 2012
The C. elegans nervous system is particularly well suited for optogenetic analyses of circuit function: Essentially all connections have been mapped, and light can be directed at the neuron of interest in the freely moving, transparent animals, while ...
Erbguth, Karen, Gottschalk, Alexander, Hegemann, Peter, Prigge, Matthias, Schneider, Franziska   +4 more
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Optogenetics in primate cortical networks

Frontiers in Neuroanatomy, 2023
The implementation of optogenetics in studies on non-human primates has generally proven quite difficult, but recent successes have paved the way for its rapid increase.
Sam Merlin, Trichur Vidyasagar, Trichur Vidyasagar   +2 more
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Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
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Controlling protein stability with SULI, a highly sensitive tag for stabilization upon light induction

Nature Communications, 2023
Optogenetics tools for precise temporal and spatial control of protein abundance are valuable in studying diverse complex biological processes. In the present study, we engineer a monomeric tag of stabilization upon light induction (SULI) for yeast and ...
Miaowei Mao, Yajie Qian, Wenyao Zhang, Siyu Zhou, Zefeng Wang, Xianjun Chen, Yi Yang   +6 more
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