Results 201 to 210 of about 20,290 (227)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Evaluation of Lipid Nanoparticles as Vehicles for Optogenetic Delivery in Primary Cortical Neurons. [PDF]

Pharmaceutics
Celdrán JD, Humphreys L, Verdú MJ, González D, Soto-Sánchez C, Martínez-Navarrete G, Enríquez L, Maldonado I, Gallego I, Mashal M, Attia N, Puras G, Pedraz JL, Fernández E.   +13 more
europepmc   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi, Sunghoon Lee, Tomoyuki Yokota, Takao Someya   +3 more
wiley   +1 more source

Sensing a rainbow of colors: algal photoreceptors. [PDF]

Front Plant Sci
Hallmann A.
europepmc   +1 more source

Lateral hypothalamus and eating: cell types, molecular identity, anatomy, temporal dynamics and functional roles. [PDF]

Exp Mol Med
Cheon DH, Park S, Park J, Koo M, Kim HH, Han S, Choi HJ.   +6 more
europepmc   +1 more source

Acousto-optogenetics bandpass stabilizer: A programmable platform for mapping single-cell phenotypic life trajectories. [PDF]

Mater Today Bio
Wang Y, Quan Y, Zhou S, Zhou Y.
europepmc   +1 more source

Altered Dopamine Signaling in Extinction-Deficient Mice. [PDF]

eNeuro
Gunduz-Cinar O, Fritz EM, Xia M, Van Leer E, Crow N, Holmes A, Singewald N.   +6 more
europepmc   +1 more source

Regulatory aspects of optogenetic research and therapy for retinitis pigmentosa under EU law. [PDF]

Front Med Technol
Freise J.
europepmc   +1 more source

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Bioluminescence-Optogenetics

2021
In this chapter, we introduce a relatively new, emerging method for molecular neuromodulation-bioluminescence-optogenetics. Bioluminescence-optogenetics is mediated by luminopsin fusion proteins-light-sensing opsins fused to light-emitting luciferases.
Ken, Berglund, Matthew A, Stern, Robert E, Gross   +2 more
openaire   +2 more sources

Fiberless Optogenetics

2021
Optogenetics, which relies on the use of photons to manipulate cellular and subcellular processes, has emerged as an important tool that has transformed several fields including neuroscience. Improvement of optogenetic topographies, together with integration with complementary tools such as electrophysiology, imaging, anatomical and behavioral analysis,
Srikanta, Chowdhury, Akihiro, Yamanaka
openaire   +2 more sources