Results 21 to 30 of about 20,290 (227)
Prospects for optogenetic augmentation of brain function
Frontiers in Systems Neuroscience, 2015 The ability to optically control neural activity opens up possibilities for the restoration of normal function following neurological disorders. The temporal precision, spatial resolution and neuronal specificity that optogenetics offers is unequalled by
Sarah eJarvis +3 more
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AAV1 is the optimal viral vector for optogenetic experiments in pigeons (Columba livia)
Communications Biology, 2021 Rook et al. establish a viral gene transfer system to perform optogenetics in pigeons. They deliver ChR2 via AAV1 into the visual entopallium and show its behavioral relevance for contrast perception, verifying the applicability of optogenetics in an ...
Noemi Rook +6 more
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Bioluminescence-Driven Optogenetics
Life, 2020 Bioluminescence-based technologies are among the most commonly used methods to quantify and visualise physiology at the cellular and organismal levels.
Macià Sureda-Vives, Karen S. Sarkisyan
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The Impact of Optogenetics on Regenerative Medicine
Applied Sciences, 2019 Optogenetics is a novel strategic field that combines light (opto-) and genetics (genetic) into applications able to control the activity of excitable cells and neuronal circuits.
Gianrico Spagnuolo +5 more
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Applications and challenges of rhodopsin-based optogenetics in biomedicine
Frontiers in Neuroscience, 2022 Optogenetics is an emerging bioengineering technology that has been rapidly developed in recent years by cross-integrating optics, genetic engineering, electrophysiology, software control, and other disciplines.
Hanci Zhang +9 more
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Proceedings of the National Academy of Sciences, 2013 Sarah C P, Williams, Karl, Deisseroth
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Optogenetic neuromodulation with gamma oscillation as a new strategy for Alzheimer disease: a narrative review [PDF]
Journal of Yeungnam Medical Science, 2022 The amyloid hypothesis has been considered a major explanation of the pathogenesis of Alzheimer disease. However, failure of phase III clinical trials with anti-amyloid-beta monoclonal antibodies reveals the need for other therapeutic approaches to treat
Haneol Ko, Sang-Pil Yoon
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Biosensors, 2021 The mammalian olfactory system has an amazing ability to distinguish thousands of odorant molecules at the trace level. Scientists have made great achievements on revealing the olfactory sensing mechanisms in decades; even though many issues need ...
Ping Zhu +6 more
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Behavioral optogenetics in nonhuman primates; a psychological perspective
Current Research in Neurobiology, 2023 Optogenetics has been a promising and developing technology in systems neuroscience throughout the past decade. It has been difficult though to reliably establish the potential behavioral effects of optogenetic perturbation of the neural activity in ...
Arash Afraz
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A Light Wand to Untangle the Myocardial Cell Network
Methods and Protocols, 2019 The discovery of optogenetics has revolutionized research in neuroscience by providing the tools for noninvasive, cell-type selective modulation of membrane potential and cellular function in vitro and in vivo. Rhodopsin-based optogenetics has later been
Tania Zaglia +2 more
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