Results 41 to 50 of about 58,764 (371)
Tools for Controlling Activity of Neural Circuits Can Boost Gastrointestinal Research [PDF]
, 2016 We thank Prof U. G. Knaus and T. C. Collin for critical reading of the manuscript. GA is supported by the European Crohn's and Colitis Organization (ECCO) (J/15/2) and by the National Childrens' Research Centre (K/12/1). GD is supported by the University
Aviello, Gabriella, D'Agostino, Giuseppe
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Rods progressively escape saturation to drive visual responses in daylight conditions
Nature Communications, 2017 Rod photoreceptors are thought to be saturated under bright light. Here, the authors describe the physiological parameters that mediate response saturation of rod photoreceptors in mouse retina, and show that rods can drive visual responses in photopic ...
Alexandra Tikidji-Hamburyan +14 more
doaj +1 more source
AAV1 is the optimal viral vector for optogenetic experiments in pigeons (Columba livia)
Communications Biology, 2021 Rook et al. establish a viral gene transfer system to perform optogenetics in pigeons. They deliver ChR2 via AAV1 into the visual entopallium and show its behavioral relevance for contrast perception, verifying the applicability of optogenetics in an ...
Noemi Rook +6 more
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Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo [PDF]
, 2013 Cyclic AMP (cAMP) is a ubiquitous second messenger that regulates a variety of essential processes in diverse cell types, functioning via cAMP-dependent effectors such as protein kinase A (PKA) and/or exchange proteins directly activated by cAMP (EPAC ...
Akbari +60 more
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Photonic Nanojet‐Mediated Optogenetics
Advancement of science, 2022 Optogenetics has become a widely used technique in neuroscience research, capable of controlling neuronal activity with high spatiotemporal precision and cell‐type specificity.
Jinghui Guo +22 more
semanticscholar +1 more source
Prospects for optogenetic augmentation of brain function
Frontiers in Systems Neuroscience, 2015 The ability to optically control neural activity opens up possibilities for the restoration of normal function following neurological disorders. The temporal precision, spatial resolution and neuronal specificity that optogenetics offers is unequalled by
Sarah eJarvis +3 more
doaj +1 more source
Optogenetic neuromodulation with gamma oscillation as a new strategy for Alzheimer disease: a narrative review [PDF]
Journal of Yeungnam Medical Science, 2022 The amyloid hypothesis has been considered a major explanation of the pathogenesis of Alzheimer disease. However, failure of phase III clinical trials with anti-amyloid-beta monoclonal antibodies reveals the need for other therapeutic approaches to treat
Haneol Ko, Sang-Pil Yoon
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Timing Control of Single Neuron Spikes with Optogenetic Stimulation [PDF]
, 2018 This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W. +3 more
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Optogenetics, physiology, and emotions [PDF]
Frontiers in Behavioral Neuroscience, 2013 Optogenetics is a powerful tool for investigating causal links between neural circuits and behavior. In recent years, optogenetic studies have expanded into the emotional realm, elucidating new facts about the circuits that underlie anxiety, depression, and reward.
Antonello Bonci, Alexxai V. Kravitz
openaire +4 more sources
Photonics, 2019 Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this purpose since it allows us to study the functionality of neuronal ...
Elena Montagni +3 more
doaj +1 more source