Results 51 to 60 of about 20,290 (227)
The Journal of the Institute of Image Information and Television Engineers, 2012 This chapter defines optogenetics as an experiment that uses a combination of genetic manipulation and optics. Optogenetics can be used for studies of the autonomic areas of the brain and provides tools for specific control of phenotypically identified groups of neurons and more recently, astrocytes.
Takashi Tokuda, Jun Ohta
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Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
Advanced Science, EarlyView.This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz +20 more
wiley +1 more source
Neuronal optogenetics as a new topic of technology assessment?
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und PraxisThis article is intended as a sketchy reflection on the question of the extent to which neuronal optogenetics could become a future topic of technology assessment (TA).
Hans Zillmann
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Towards circuit optogenetics [PDF]
Current Opinion in Neurobiology, 2018 Optogenetics neuronal targeting combined with single-photon wide-field illumination has already proved its enormous potential in neuroscience, enabling the optical control of entire neuronal networks and disentangling their role in the control of specific behaviors. However, establishing how a single or a sub-set of neurons controls a specific behavior,
Chen, I-Wen +2 more
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Advanced Science, EarlyView.Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong +10 more
wiley +1 more source
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
Nature Communications, 2019 Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during ...
Yi Chen +4 more
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Advanced Science, EarlyView.This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber +12 more
wiley +1 more source
Optogenetics and Its Transformative Role in Tissue Engineering and Regenerative Medicine
Nano SelectOptogenetics, a revolutionary technique leveraging light stimulation for precise cellular control, holds immense potential in regenerative medicine. Offering unparalleled spatial and temporal accuracy, the entrance of optogenetics into tissue engineering
Emine Camcıoglu +2 more
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