Results 61 to 70 of about 55,224 (387)
Voltage imaging and optogenetics reveal behavior dependent changes in hippocampal dynamics
A technology that simultaneously records membrane potential from multiple neurons in behaving animals will have a transformative effect on neuroscience research1,2.
Yoav Adam+23 more
semanticscholar +1 more source
Optogenetics and Chemogenetics [PDF]
Optogenetics and chemogenetics provide the ability to modulate neurons in a type- and region-specific manner. These powerful techniques are useful to test hypotheses regarding the neural circuit mechanisms of general anesthetic end points such as hypnosis and analgesia.
Ken Solt+3 more
openaire +2 more sources
Real-time optical manipulation of cardiac conduction in intact hearts [PDF]
Optogenetics has provided new insights in cardiovascular research, leading to new methods for cardiac pacing, resynchronization therapy and cardioversion.
Bocchi, L.+16 more
core +2 more sources
Flight and freezing are two vital defensive behaviors in the process of avoiding natural enemies in mice. We investigated the neural activity in dPAG nuclei of mice under two defensive behaviors, and found different coding features between flight and freezing behaviors. Abstract Background Flight and freezing are two vital defensive behaviors that mice
Denghui Liu+5 more
wiley +1 more source
Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this purpose since it allows us to study the functionality of neuronal ...
Elena Montagni+3 more
doaj +1 more source
Light has become established as a tool not only to visualize and investigate but also to steer biological systems. This review starts by discussing the unique features that make light such an effective control input in biology.
Armin Baumschlager, M. Khammash
semanticscholar +1 more source
Prospects for optogenetic augmentation of brain function
The ability to optically control neural activity opens up possibilities for the restoration of normal function following neurological disorders. The temporal precision, spatial resolution and neuronal specificity that optogenetics offers is unequalled by
Sarah eJarvis+3 more
doaj +1 more source
The mammalian olfactory system has an amazing ability to distinguish thousands of odorant molecules at the trace level. Scientists have made great achievements on revealing the olfactory sensing mechanisms in decades; even though many issues need ...
Ping Zhu+6 more
doaj +1 more source
Wireless closed-loop optogenetics across the entire dorsoventral spinal cord in mice
Optoelectronic systems can exert precise control over targeted neurons and pathways throughout the brain in untethered animals, but similar technologies for the spinal cord are not well established.
C. Kathe+21 more
semanticscholar +1 more source
The Optogenetic Catechism [PDF]
An emerging set of methods enables an experimental dialogue with biological systems composed of many interacting cell types—in particular, with neural circuits in the brain. These methods are sometimes called “optogenetic” because they use light-responsive proteins (“opto-”) encoded in DNA (“-genetic”).
openaire +3 more sources