Results 61 to 70 of about 58,764 (371)
The optogenetic (r)evolution [PDF]
Molecular Genetics and Genomics, 2011 Optogenetics is a rapidly evolving field of technology that allows optical control of genetically targeted biological systems at high temporal and spatial resolution. By heterologous expression of light-sensitive microbial membrane proteins, opsins, cell type-specific depolarization or silencing can be optically induced on a millisecond time scale ...
Rein, M.L., Deussing, J.M.
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Behavioral optogenetics in nonhuman primates; a psychological perspective
Current Research in Neurobiology, 2023 Optogenetics has been a promising and developing technology in systems neuroscience throughout the past decade. It has been difficult though to reliably establish the potential behavioral effects of optogenetic perturbation of the neural activity in ...
Arash Afraz
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Advances in Biology, 2021 Light has become established as a tool not only to visualize and investigate but also to steer biological systems. This review starts by discussing the unique features that make light such an effective control input in biology.
Armin Baumschlager, M. Khammash
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A Light Wand to Untangle the Myocardial Cell Network
Methods and Protocols, 2019 The discovery of optogenetics has revolutionized research in neuroscience by providing the tools for noninvasive, cell-type selective modulation of membrane potential and cellular function in vitro and in vivo. Rhodopsin-based optogenetics has later been
Tania Zaglia +2 more
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Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
, 2012 Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong +5 more
core +2 more sources
ACS Nano, 2019 Since the isolation of graphene in 2004, there has been an exponentially growing number of reports on layered two-dimensional (2D) materials for applications ranging from protective coatings to biochemical sensing.
Adam Bolotsky +7 more
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Herald of the Russian Academy of Sciences, 2019 In this article the authors discuss electronic and optogenetic approaches for degenerative (blind) retina prosthesis as the main strategies for the restoration of vision to blind people. Primary attention is devoted to the prospects of developing retinal prostheses for the blind using modern optogenetic methods, and rhodopsins, which are photosensitive
M. A. Ostrovsky +3 more
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Optogenetics: Emerging strategies for neuropathic pain treatment
Frontiers in Neurology, 2022 Neuropathic pain (NP) is a chronic health condition that presents a significant burden on patients, society, and even healthcare systems. However, in recent years, an emerging field in the treatment of neuropathic pain – optogenetic technology has dawned,
Siyu Li +3 more
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Identifying specific prefrontal neurons that contribute to autism-associated abnormalities in physiology and social behavior. [PDF]
, 2017 Functional imaging and gene expression studies both implicate the medial prefrontal cortex (mPFC), particularly deep-layer projection neurons, as a potential locus for autism pathology.
Brumback, AC +9 more
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Nature Communications, 2021 Optogenetics combined with electrical recording has emerged as a powerful tool for investigating causal relationships between neural circuit activity and function.
Liang Zou +6 more
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