Results 71 to 80 of about 43,018 (315)

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Illuminating pathogen-host intimacy through optogenetics.

PLoS Pathogens, 2018
The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience ...
Ruben Dario Arroyo-Olarte, Laura Thurow, Vera Kozjak-Pavlovic, Nishith Gupta   +3 more
doaj   +1 more source

Roadmap on semiconductor-cell biointerfaces. [PDF]

, 2018
This roadmap outlines the role semiconductor-based materials play in understanding the complex biophysical dynamics at multiple length scales, as well as the design and implementation of next-generation electronic, optoelectronic, and mechanical devices ...
Anikeeva, Polina, Bao, Zhenan, Benfenati, Fabio, Bezanilla, Francisco, Cao, Yuhong, Carvalho-de-Souza, João L, Cestellos-Blanco, Stefano, Cifra, Michal, Galli, Giulia, Gorodetsky, Alon A, Gygi, Francois, Havelka, Daniel, Hjort, Martin, Jiang, Yuanwen, Kautz, Rylan, Kim, Samuel S, Krivosudský, Ondrej, Lanzani, Guglielmo, Liu, Jia, Lu, Timothy K, Melosh, Nicholas, Rogers, John A, Tian, Bozhi, Xu, Shuai, Yang, Peidong   +24 more
core   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Thermal constraints on in vivo optogenetic manipulations. [PDF]

, 2019
A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive.
Kreitzer, Anatol C, Liu, Max H, Owen, Scott F   +2 more
core  

Optogenetics

The Journal of the Institute of Image Information and Television Engineers, 2012
This chapter defines optogenetics as an experiment that uses a combination of genetic manipulation and optics. Optogenetics can be used for studies of the autonomic areas of the brain and provides tools for specific control of phenotypically identified groups of neurons and more recently, astrocytes.
Takashi Tokuda, Jun Ohta
openaire   +4 more sources

Thermally Drawn Multifunctional All‐Hydrogel Fibers for Anti‐Fibrotic and Multimodal Neural Interfaces

Advanced Materials, EarlyView.
Hydrogels demonstrate material properties that mimic the mechanical and chemical environments of biological tissues. Yet, they face challenges during their integration into 3D interfaces. By identifying a class of thermoplastic hydrogels, a strategy is developed to pattern hydrogels in thermally drawn fibers.
Changhoon Sung, Kum Seok Nam, Yeji Kim, Honey Kang, Kanghyeon Kim, Chanwoong Yoon, Somin Lee, Ain Chung, Jiheong Kang, Young‐Gyun Park, Alan Jung Park, Haider Butt, Hyunwoo Yuk, Seongjun Park   +13 more
wiley   +1 more source

Neuronal optogenetics as a new topic of technology assessment?

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
This article is intended as a sketchy reflection on the question of the extent to which neuronal optogenetics could become a future topic of technology assessment (TA).
Hans Zillmann
doaj   +1 more source

Photonic Nanojet‐Mediated Optogenetics

Advanced Science, 2022
Optogenetics has become a widely used technique in neuroscience research, capable of controlling neuronal activity with high spatiotemporal precision and cell‐type specificity.
Jinghui Guo, Yong Wu, Zhiyong Gong, Xixi Chen, Fei Cao, Shashwati Kala, Zhihai Qiu, Xinyi Zhao, Jun‐jiang Chen, Dongming He, Taiheng Chen, Rui Zeng, Jiejun Zhu, Kin Fung Wong, Suresh Murugappan, Ting Zhu, Quanxiang Xian, Xuandi Hou, Ye Chun Ruan, Baojun Li, Yu Chao Li, Yao Zhang, Lei Sun   +22 more
doaj   +1 more source

Towards circuit optogenetics [PDF]

Current Opinion in Neurobiology, 2018
Optogenetics neuronal targeting combined with single-photon wide-field illumination has already proved its enormous potential in neuroscience, enabling the optical control of entire neuronal networks and disentangling their role in the control of specific behaviors. However, establishing how a single or a sub-set of neurons controls a specific behavior,
Chen, I-Wen, Papagiakoumou, Eirini, Emiliani, Valentina   +2 more
openaire   +3 more sources