Results 171 to 180 of about 2,970 (183)

Lilium spp., as unnoticed environmental vector, spreading OptrA-carrying Enterococcus spp.

Science of The Total Environment, 2022
Flower is an essential element in the human lifestyle but its role in disseminating antimicrobial resistance (AMR) between the environment and humans is unclear. In this study, we screened fresh flowers (Lilium spp.) collected from planting bases, market and florists in Guangzhou China aiming to investigate the prevalence of AMR genes, particularly cfr,
Yang, Yu, Xin-Qing, Ye, Hua-Qing, Liang, Zi-Xing, Zhong, Ke, Cheng, Jian, Sun, Xiao-Ping, Liao, Ya-Hong, Liu   +7 more
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Detection of the enterococcal oxazolidinone/phenicol resistance gene optrA in Campylobacter coli

Veterinary Microbiology, 2020
The transferable optrA gene encodes an ABC-F protein which confers resistance to oxazolidinones and phenicols, and has so far been detected exclusively in Gram-positive bacteria, including enterococci, staphylococci and streptococci. Here, we identified for the first time the presence of optrA in naturally occurring Gram-negative bacteria.
Dejun, Liu, Dawei, Yang, Xiao, Liu, Xing, Li, Andrea T, Feßler, Zhangqi, Shen, Jianzhong, Shen, Stefan, Schwarz, Yang, Wang   +8 more
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Linezolid-resistant ST872 Enteroccocus faecium harbouring optrA and cfr (D) oxazolidinone resistance genes

International Journal of Antimicrobial Agents, 2020
Letter to the ...
Stanley Pang, Peter Boan, Terence Lee, Shane Gangatharan, Shu Jin Tan, Denise Daley, Yung Thin Lee, Geoffrey W. Coombs   +7 more
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A novel inhibitor of the new antibiotic resistance protein OptrA

Chemical Biology & Drug Design, 2018
The antibiotic resistance (ARE) subfamily of ABC (ATP‐binding cassette) proteins confers resistance to a variety of clinically important ribosome‐targeting antibiotics and plays an important role in infections caused by pathogenic bacteria. However, inhibitors of ARE proteins have rarely been reported. Here, OptrA, a new member of the ARE proteins, was
Xiaobo Zhong, Hua Xiang, Tiedong Wang, Ling Zhong, Di Ming, Linyan Nie, Fengjiao Cao, Bangbang Li, Junjie Cao, Dan Mu, Ke Ruan, Lin Wang, Dacheng Wang   +12 more
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Characterization of cross-resistance gene optrA-carrying Campylobacter coli

Veterinary Microbiology
Campylobacter is a significant foodborne pathogen causing human campylobacteriosis. The optrA gene, which encodes an ABC-F protein, confers cross-resistance to oxazolidinones and phenicols, and recent studies have identified the emergence of optrA in Campylobacter. However, detailed information of optrA- carrying C. coli from food-producing animals and
Jin, Kang, Shuigen, Wan, Wenbo, Zhao, Shihong, Li, Wenjun, Li, Hao, Li, Yong, Liu, Hexiang, Huang, Chunyan, Xu, Xiang-Dang, Du, Hong, Yao   +10 more
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First report of the optrA-carrying multidrug resistance genomic island in Campylobacter jejuni isolated from pigeon meat

International Journal of Food Microbiology, 2021
Campylobacter spp., such as Campylobacter jejuni and Campylobacter coli, are important zoonotic Gram-negative pathogens that cause acute intestinal diseases in humans. The optrA gene, encoding an ATP-binding cassette F (ABC-F) protein that confers resistance to oxazolidinones and phenicols, has been found in C. coli in China.
Shengjun, Tang, Runshi, Yang, Qingping, Wu, Yu, Ding, Zhi, Wang, Jumei, Zhang, Tao, Lei, Shi, Wu, Feng, Zhang, Weipei, Zhang, Liang, Xue, Youxiong, Zhang, Xianhu, Wei, Rui, Pang, Juan, Wang   +14 more
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IS6 family insertion sequences promote optrA dissemination between plasmids varying in transfer abilities

Applied Microbiology and Biotechnology
Plasmids are the primary vectors for intercellular transfer of the oxazolidinone and phenicol cross-resistance gene optrA, while insertion sequences (ISs) are mobile genetic elements that can mobilize plasmid-borne optrA intracellularly. However, little is known about how the IS-mediated intracellular mobility facilitates the dissemination of the optrA
Shihai Liu, Xiaoxiao Yang, Ruichao Li, Shaolin Wang, Ziming Han, Min Yang, Yu Zhang   +6 more
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Global spread of the linezolid-resistant Enterococcus faecalis ST476 clonal lineage carrying optrA

Journal of Antimicrobial Chemotherapy
Abstract Objectives To investigate the global distribution of an optrA-harbouring linezolid-resistant Enterococcus faecalis ST476 clonal lineage. Methods Comprehensive searches of the NCBI database were performed to identify published
Andrea Brenciani, Marzia Cinthi, Sonia Nina Coccitto, Francesca Romana Massacci, Elisa Albini, Lucilla Cucco, Marta Paniccià, Ana R Freitas, Stefan Schwarz, Eleonora Giovanetti, Chiara Francesca Magistrali   +10 more
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Detection of optrA-positive enterococci clinical isolates in Belgium

European Journal of Clinical Microbiology & Infectious Diseases, 2019
M. Angeles Argudín, S. Youzaga, M. Dodémont, A. Heinrichs, S. Roisin, A. Deplano, C. Nonhoff, M. Hallin   +7 more
openaire   +2 more sources