Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm [PDF]
Journal of Global Antimicrobial Resistance, 2020 Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa +7 more
doaj +7 more sources
Oxazolidinone resistance genes in florfenicol-resistant enterococci from beef cattle and veal calves at slaughter [PDF]
Frontiers in Microbiology, 2023 BackgroundLinezolid is a critically important oxazolidinone antibiotic used in human medicine. Although linezolid is not licensed for use in food-producing animals, the use of florfenicol in veterinary medicine co-selects for oxazolidinone resistance ...
Magdalena Nüesch-Inderbinen +6 more
doaj +5 more sources
Carriage of linezolid-resistant enterococci (LRE) among humans and animals in Nigeria: coexistence of the cfr, optrA, and poxtA genes in Enterococcus faecium of animal origin [PDF]
Journal of Global Antimicrobial Resistance, 2023 : Objectives: In contrast to increasing reports of the emergence of linezolid-resistant enterococci (LRE) emanating from many countries in Europe, Asia, and North America, data on its status and dissemination from the African continent remain scarce ...
Emmanuel O. Ngbede +7 more
doaj +5 more sources
Detection of Genes Related to Linezolid Resistance (poxtA, cfr, and optrA) in Clinical Isolates of Enterococcus spp. from Humans: A First Report from Iran [PDF]
Advanced Biomedical Research, 2023 Background: Enterococci may develop resistance to linezolid through chromosomal mutations that involve specific linezolid resistance genes, such as cfr, optrA, and poxtA.
Majid Torabi +2 more
doaj +4 more sources
Linezolid Resistance Genes and Mutations among Linezolid-Susceptible Enterococcus spp.—A Loose Cannon? [PDF]
AntibioticsThe National Reference Centre for Enterococci receives an increasing number of linezolid-resistant Enterococcus isolates. Linezolid (LIN) resistance is mediated by G2576T 23S rDNA gene mutations and/or acquisition of resistance genes (cfr, optrA, poxtA).
Jennifer K. Bender +5 more
doaj +4 more sources
Genomic analysis of Enterococcus faecium co-carrying optrA and poxtA from a swine farm: dissemination across the human–animal–environment interface [PDF]
BMC MicrobiologyBackground The transferable resistance genes optrA and poxtA mediate cross-resistance to florfenicol and linezolid, posing serious challenges to both veterinary and human healthcare. Swine farms serve as critical ecological niches for the development and
Panpan Xia +8 more
doaj +2 more sources
Genomic insights into the global dissemination of linezolid resistance genes in Enterococcus faecium [PDF]
Frontiers in MicrobiologyBackgroundTransferable linezolid resistance determinants in Enterococcus faecium, particularly optrA, poxtA, and cfr, have raised increasing global concern due to their potential dissemination across clinical, animal, food, and environmental reservoirs ...
Xiaoxiao Yuan +6 more
doaj +2 more sources
Validating a screening agar for linezolid-resistant enterococci [PDF]
BMC Infectious Diseases, 2019 Background Linezolid is an alternative treatment option for infections with multidrug-resistant Gram-positive bacteria including vancomycin-resistant enterococci. Some countries report an increasing number of isolates with resistance to linezolid.
Guido Werner +4 more
doaj +2 more sources
Molecular characterization of florfenicol and oxazolidinone resistance in Enterococcus isolates from animals in China [PDF]
Frontiers in Microbiology, 2022 Florfenicol is widely used for the treatment of bacterial infections in domestic animals. The aim of this study was to analyze the molecular mechanisms of florfenicol and oxazolidinone resistance in Enterococcus isolates from anal feces of domestic ...
Pingping Li +29 more
doaj +3 more sources
Characterization of a Tigecycline-, Linezolid- and Vancomycin-Resistant Clinical Enteroccoccus faecium Isolate, Carrying vanA and vanB Genes [PDF]
Infectious Diseases and Therapy, 2023 Introduction Increasing incidence of Enterococcus faecium resistant to key antimicrobials used in therapy of hospitalized patients is a worrisome phenomenon observed worldwide.
Ewa Wardal +5 more
doaj +2 more sources