Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm [PDF]
Journal of Global Antimicrobial Resistance, 2020 Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa +7 more
doaj +6 more sources
Identification of the Multiresistance Gene poxtA in Oxazolidinone-Susceptible Staphylococcus haemolyticus and Staphylococcus saprophyticus of Pig and Feed Origins [PDF]
Pathogens, 2021 Previous studies on the prevalence and transmission mechanism of oxazolidinone resistance gene poxtA in CoNS are lacking, which this study addresses. By screening 763 CoNS isolates from different sources of several livestock farms in Guangdong, China ...
Lin Chen +7 more
doaj +4 more sources
Detection of an Enterococcus faecium Carrying a Double Copy of the PoxtA Gene from Freshwater River, Italy [PDF]
Antibiotics, 2022 Oxazolidinones are valuable antimicrobials that are used to treat severe infections due to multidrug-resistant (MDR) Gram-positive bacteria. However, in recent years, a significant spread of clinically relevant linezolid-resistant human bacteria that is ...
Marzia Cinthi +5 more
doaj +4 more sources
Journal of Global Antimicrobial ResistanceObjectives: The poxtA gene is a transferable linezolid-resistance gene that encodes an ATP-binding cassette F protein that prevents linezolid from inhibiting protein synthesis.
Fernando Lázaro-Perona +8 more
doaj +5 more sources
Transferable linezolid resistance genes (optrA and poxtA) in enterococci derived from livestock compost at Japanese farms [PDF]
Journal of Global Antimicrobial ResistanceObjectives: Linezolid is a last-resort antimicrobial in human clinical settings to treat multidrug-resistant Gram-positive bacterial infections. Mobile linezolid resistance genes (optrA, poxtA, and cfr) have been detected in various sources worldwide ...
Akira Fukuda +3 more
doaj +7 more sources
Advanced Biomedical Research, 2023 Background: Enterococci may develop resistance to linezolid through chromosomal mutations that involve specific linezolid resistance genes, such as cfr, optrA, and poxtA.
Majid Torabi +2 more
doaj +4 more sources
Antibiotics, 2022 Enterococci are part of the commensal gut microbiota of mammals, with Enterococcus faecalis and Enterococcus faecium being the most clinically relevant species.
Joana Gião +4 more
doaj +4 more sources
Carriage of linezolid-resistant enterococci (LRE) among humans and animals in Nigeria: coexistence of the cfr, optrA, and poxtA genes in Enterococcus faecium of animal origin [PDF]
Journal of Global Antimicrobial Resistance, 2023 : Objectives: In contrast to increasing reports of the emergence of linezolid-resistant enterococci (LRE) emanating from many countries in Europe, Asia, and North America, data on its status and dissemination from the African continent remain scarce ...
Emmanuel O. Ngbede +7 more
doaj +5 more sources
Genetic features of the poxtA linezolid resistance gene in human enterococci from France
Journal of Antimicrobial Chemotherapy, 2021 Abstract Objectives To describe the prevalence of poxtA among clinical linezolid-resistant enterococci (LRE) collected in France from 2016 to 2020 and to extensively characterize its genetic supports and environments.
Loren Dejoies +9 more
openaire +4 more sources
Genetic Characterization of a Linezolid- and Penicillin-Resistant <i>Enterococcus hirae</i> Isolate Co-Harboring <i>poxtA</i> and <i>pbp5fm</i>. [PDF]
Transbound Emerg DisLinezolid and penicillin are critical for treating multidrug resistant (MDR) Gram‐positive infections, but the emergence of resistance to both seriously threatens public health. Here, we first report the cocarrying poxtA (oxazolidinone resistance) and pbp5fm
Huang J +6 more
europepmc +4 more sources