Results 1 to 10 of about 973 (111)

Identification of the Phenicol Efflux Gene fexB and Its Co‐Occurrence With the Oxazolidinone/Phenicol Resistance Gene optrA in Avian Campylobacter jejuni Isolates From Tunisia [PDF]

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Campylobacter jejuni, a major foodborne and zoonotic pathogen linked to poultry, is showing rising resistance to last‐resort antimicrobials like oxazolidinones and phenicols. Such resistance threatens both animal and human health. Its ability to acquire genes from gram‐positive bacteria highlights the need for surveillance in avian ...
Manel Gharbi, Chadlia Hamdi, Mohammed Abdo Saghir Abbas, Safa Hamrouni, Abderrazak Maaroufi, Mohamed Salah Abbassi   +5 more
wiley   +2 more sources

Transferable optrA-mediated linezolid resistance in enterococci from high-altitude river sediments of Gilgit-Baltistan, Pakistan [PDF]

Applied and Environmental Microbiology
Environmental dissemination of antimicrobial resistance is a growing global concern. This study investigated the occurrence, genetic context, and mobility of the oxazolidinone resistance genes in enterococci isolated from high-altitude river sediments in
Serena Simoni, Andrea Brenciani, Alessandra Di Gregorio, Francesca Romana Massacci, Lucilla Cucco, Maisoor Ahmed Nafees, Saif Ud Din, Nelofar Hanif, Stefania Gorbi, Francesco Regoli, Eleonora Giovanetti, Carla Vignaroli   +11 more
doaj   +2 more sources

Genomic analysis of Enterococcus faecium co-carrying optrA and poxtA from a swine farm: dissemination across the human–animal–environment interface [PDF]

BMC Microbiology
Background The transferable resistance genes optrA and poxtA mediate cross-resistance to florfenicol and linezolid, posing serious challenges to both veterinary and human healthcare. Swine farms serve as critical ecological niches for the development and
Panpan Xia, Huimin Wu, Wanzhao Chen, Rui Tian, Mengqi Yang, Shuqin Xu, Chenhui Zhang, Tianyuan Zeng, Lining Xia   +8 more
doaj   +2 more sources

Prevalence and genetic characterization of Gram-positive bacteria carrying linezolid resistance genes in vegetables [PDF]

Environmental Microbiome
Background Linezolid resistance poses an ecological threat to the health of humans, animals, and the environment. Vegetable may serve as reservoirs for resistance genes, yet its prevalence remain underexplored.
Yinglin Xu, Weiyi Shen, Kaiqi Zeng, Rong Zhang, Jiachang Cai   +4 more
doaj   +2 more sources

Molecular Epidemiology and Genetic Context of optrA-Carrying Linezolid-Resistant Enterococci from Humans and Animals in South Korea [PDF]

Antibiotics
Objectives: Linezolid resistance among Enterococcus species poses a growing clinical and public health concern, especially due to the dissemination of transferable resistance genes, such as optrA.
Younggwon On, Sung Young Lee, Jung Sik Yoo, Jung Wook Kim   +3 more
doaj   +2 more sources

Emergence of Linezolid Resistance Genes optrA and cfr(D) in an Enterococcus saccharolyticus from Chicken [PDF]

Antibiotics
Background: The emergence of linezolid resistance, mediated by genes such as optrA and cfr(D), poses a growing public health threat. While these genes have been detected in clinical and animal-derived Enterococcus species, their presence in underexplored
Xun Gao, Xiao Luo, Ruorou Qian, Guolong Gao, Jinghao Liu, Junhao Hong, Chao Yue, Jian-Hua Liu, Yi-Yun Liu   +8 more
doaj   +2 more sources

Genomic and clinical characterization of linezolid resistance in Enterococcus species from cancer patients in China [PDF]

BMC Infectious Diseases
Background Immunocompromised cancer patients represent a susceptible population for enterococcal infections. While linezolid remains the primary therapeutic option for vancomycin-resistant Enterococcus (VRE) infections, the emergence of linezolid ...
Qun Wang, Xiaoyu Zhang, Weixing Wu, Zhenghua Xie, Yongping Lin, Li Zhang   +5 more
doaj   +2 more sources

Emergence of linezolid-resistant Enterococcus cecorum clade F harboring optrA/fexA causing enterococcal spondylitis in commercial broilers in China [PDF]

BMC Microbiology
Background Enterococcus cecorum, long regarded as a commensal bacterium in the avian gut, has recently emerged as a significant pathogen causing enterococcal spondylitis.
Fanrun Meng, Defang Zhou, Ruiqi Li, Feng Lang, Bin Xiang, Liangyu Yang, Ziqiang Cheng   +6 more
doaj   +2 more sources

Various Mobile Genetic Elements Involved in the Dissemination of the Phenicol-Oxazolidinone Resistance Gene optrA in the Zoonotic Pathogen Streptococcus suis: a Nonignorable Risk to Public Health

Microbiology Spectrum, 2023
The rapid increase of phenicol-oxazolidinone (PhO) resistance in Streptococcus suis due to transferable resistance gene optrA is a matter of concern. However, genetic mechanisms for the dissemination of the optrA gene remain to be discovered.
Xingyang Dai, Junjie Sun, Boqin Zhu, Mingsiyi Lv, Liye Chen, Li Chen, Xiaoming Wang, Jinhu Huang, Liping Wang   +8 more
doaj   +1 more source

Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentina

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The aim of this study was to characterize the first 14 optrA-carrying linezolid resistant E. faecalis clinical isolates recovered in seven Argentinian hospitals between 2016 and 2021.
Paula Gagetti, Diego Faccone, Paola Ceriana, Celeste Lucero, Alejandra Menocal, Grupo LRE Argentina, Alejandra Corso   +6 more
doaj   +1 more source