Results 1 to 10 of about 1,674 (204)

Characterization of a Multiresistance Plasmid Carrying the optrA and cfr Resistance Genes From an Enterococcus faecium Clinical Isolate [PDF]

Frontiers in Microbiology, 2018
Enterococcus faecium E35048, a bloodstream isolate from Italy, was the first strain where the oxazolidinone resistance gene optrA was detected outside China. The strain was also positive for the oxazolidinone resistance gene cfr.
Gianluca Morroni, Andrea Brenciani, Alberto Antonelli, Marco Maria D’Andrea, Marco Maria D’Andrea, Vincenzo Di Pilato, Simona Fioriti, Marina Mingoia, Carla Vignaroli, Oscar Cirioni, Francesca Biavasco, Pietro E. Varaldo, Gian Maria Rossolini, Gian Maria Rossolini, Eleonora Giovanetti   +14 more
doaj   +10 more sources

High prevalence and plasmidome diversity of optrA-positive enterococci in a Shenzhen community, China [PDF]

Frontiers in Microbiology
BackgroundThe emergence of optrA, which can confer resistance to phenicols and oxazolidinones in Enterococcus spp., poses a growing public health threat.Methods102 optrA-positive enterococci (OPEs) including various species were isolated from feces of ...
Yulin Fu, Zhaoju Deng, Yingbo Shen, Weizhou Wei, Qiumei Xiang, Zhiyang Liu, Kunning Hanf, Suli Huang, Suli Huang, Zexun Lv, Tingting Cao, Changfeng Peng, Rong Zhang, Xuan Zou, Jianzhong Shen, Stefan Schwarz, Stefan Schwarz, Stefan Schwarz, Yang Wang, Dejun Liu, Ziquan Lv, Yuebin Ke   +21 more
doaj   +8 more sources

Occurrence of Florfenicol and Linezolid Resistance and Emergence of optrA Gene in Campylobacter coli Isolates from Tunisian Avian Farms. [PDF]

Int J Microbiol
Campylobacter species, especially C. coli and C. jejuni, have been associated with a range of human gastrointestinal diseases. During the last two decades, due to the irrational use of antibiotics in poultry farms, high rates of antimicrobial resistance have been globally reported in C. coli and C. jejuni isolates.
Gharbi M, Tiss R, Hamdi C, Hamrouni S, Maaroufi A.   +4 more
europepmc   +5 more sources

Mechanisms of Linezolid Resistance Among Enterococci of Clinical Origin in Spain—Detection of optrA- and cfr(D)-Carrying E. faecalis [PDF]

Microorganisms, 2020
The mechanisms of linezolid resistance among 13 E. faecalis and 6 E. faecium isolates, recovered from six Spanish hospitals during 2017–2018, were investigated.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Inga Eichhorn, José Manuel Azcona-Gutiérrez, Mar Olga Pérez-Moreno, Cristina Seral, Carmen Aspiroz, Carla Andrea Alonso, Luis Torres, Juan-Ignacio Alós, Stefan Schwarz, Carmen Torres   +12 more
doaj   +3 more sources

Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus [PDF]

Molecules, 2018
The optrA gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of optrA and whether it involves antibiotic efflux or
Yingyu Wang, Xiaowei Li, Yang Wang, Stefan Schwarz, Jianzhong Shen, Xi Xia   +5 more
doaj   +3 more sources

Identification of the Phenicol Efflux Gene <i>fexB</i> and Its Co-Occurrence With the Oxazolidinone/Phenicol Resistance Gene <i>optrA</i> in Avian <i>Campylobacter jejuni</i> Isolates From Tunisia. [PDF]

Int J Microbiol
Background Campylobacter jejuni, a major foodborne and zoonotic pathogen linked to poultry, is showing rising resistance to last‐resort antimicrobials like oxazolidinones and phenicols. Such resistance threatens both animal and human health. Its ability to acquire genes from gram‐positive bacteria highlights the need for surveillance in avian ...
Gharbi M, Hamdi C, Abbas MAS, Hamrouni S, Maaroufi A.   +4 more
europepmc   +2 more sources

Characterization and comparative genomics analysis of RepA_N multi-resistance plasmids carrying optrA from Enterococcus faecalis [PDF]

Frontiers in Microbiology, 2023
IntroductionThis research aimed to investigate the antibiotic resistance of Enterococcus faecalis from swine farms in Zhejiang Province and the prevalence and transmission mechanism of oxazolidone resistance gene optrA.MethodA total of 226 Enterococcus ...
Enbao Zhang, Shuaizhou Zong, Wei Zhou, Jinzhi Zhou, Jianzhong Han, Daofeng Qu   +5 more
doaj   +3 more sources

Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm [PDF]

Journal of Global Antimicrobial Resistance, 2020
Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Susana Sanz, Carmen Olarte, Inga Eichhorn, Stefan Schwarz, Carmen Torres   +7 more
doaj   +3 more sources

Prevalence and genetic characterization of Gram-positive bacteria carrying linezolid resistance genes in vegetables [PDF]

Environmental Microbiome
Background Linezolid resistance poses an ecological threat to the health of humans, animals, and the environment. Vegetable may serve as reservoirs for resistance genes, yet its prevalence remain underexplored.
Yinglin Xu, Weiyi Shen, Kaiqi Zeng, Rong Zhang, Jiachang Cai   +4 more
doaj   +2 more sources

Genomic insights into the global dissemination of linezolid resistance genes in Enterococcus faecium [PDF]

Frontiers in Microbiology
BackgroundTransferable linezolid resistance determinants in Enterococcus faecium, particularly optrA, poxtA, and cfr, have raised increasing global concern due to their potential dissemination across clinical, animal, food, and environmental reservoirs ...
Xiaoxiao Yuan, Chao Ma, Xiaoli Cao, Zhiwei Ma, Liuli Wu, Peitao Jiang, Zhengnan Yang   +6 more
doaj   +2 more sources