Results 1 to 10 of about 2,522,619 (179)

Characterization and comparative genomics analysis of RepA_N multi-resistance plasmids carrying optrA from Enterococcus faecalis [PDF]

open access: yesFrontiers in Microbiology, 2023
IntroductionThis research aimed to investigate the antibiotic resistance of Enterococcus faecalis from swine farms in Zhejiang Province and the prevalence and transmission mechanism of oxazolidone resistance gene optrA.MethodA total of 226 Enterococcus ...
Enbao Zhang   +5 more
doaj   +4 more sources

Various Mobile Genetic Elements Involved in the Dissemination of the Phenicol-Oxazolidinone Resistance Gene optrA in the Zoonotic Pathogen Streptococcus suis: a Nonignorable Risk to Public Health

open access: yesMicrobiology Spectrum, 2023
The rapid increase of phenicol-oxazolidinone (PhO) resistance in Streptococcus suis due to transferable resistance gene optrA is a matter of concern. However, genetic mechanisms for the dissemination of the optrA gene remain to be discovered.
Xingyang Dai   +8 more
doaj   +3 more sources

Mechanisms of Linezolid Resistance Among Enterococci of Clinical Origin in Spain—Detection of optrA- and cfr(D)-Carrying E. faecalis [PDF]

open access: yesMicroorganisms, 2020
The mechanisms of linezolid resistance among 13 E. faecalis and 6 E. faecium isolates, recovered from six Spanish hospitals during 2017–2018, were investigated.
Laura Ruiz-Ripa   +12 more
doaj   +2 more sources

Linezolid-resistant Enterococcus faecalis ST16 harbouring optrA on a Tn6674-like element isolated from surface water [PDF]

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: The objective of this work was to characterise an optrA-carrying Enterococcus faecalis ST16 isolate recovered from a river water sample in Switzerland. Methods: Linezolid-resistant E.
Magdalena Nüesch-Inderbinen   +4 more
doaj   +3 more sources

An Optimized Screening Approach for the Oxazolidinone Resistance Gene optrA Yielded a Higher Fecal Carriage Rate among Healthy Individuals in Hangzhou, China

open access: yesMicrobiology Spectrum, 2022
The linezolid resistance mediated by optrA has exhibited an increasing trend among Gram-positive bacteria, which greatly limits the treatment options for severe bacterial infections.
Weiyi Shen, Yonglu Huang, Jiachang Cai
doaj   +3 more sources

Transmission of linezolid-resistant Enterococcus isolates carrying optrA and poxtA genes in slaughterhouses

open access: yesFrontiers in Sustainable Food Systems, 2023
IntroductionThe presence of linezolid-resistant enterococci found in animal-derived food has attracted attention for possible transmission to human-derived enterococci through the food chain.
Juan Ni   +11 more
doaj   +2 more sources

Genomic insights of optrA-carrying linezolid-resistant Enterococcus faecium using hybrid assembly: first report from India

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: Linezolid resistance in Enterococcus faecium is emerging worldwide. In this study, we aimed to characterise two linezolid-resistant E. faecium isolates using whole-genome sequencing.
Yamuna Devi Bakthavatchalam   +5 more
doaj   +2 more sources

Molecular characteristics of optrA-carrying Enterococcus faecalis from chicken meat in South Korea

open access: yesPoultry Science, 2020
The purpose of this study was to identify the genetic environment of optrA gene in linezolid (LZD)-resistant Enterococcus faecalis from chicken meat and to describe the probable mechanism of dissemination of the optrA gene through plasmid or chromosomal ...
Sunghyun Yoon   +4 more
doaj   +1 more source

Genome characteristics of the optrA-positive Clostridium perfringens strain QHY-2 carrying a novel plasmid type

open access: yesmSystems, 2023
Clostridium perfringens is a bacterial species of importance to both public and animal health. The gene optrA is the first gene that confers resistance to the tedizolid, a last-resort antimicrobial agent in human medicine.
Ke Wu   +15 more
doaj   +1 more source

Rapid Identification of Species, Antimicrobial‐Resistance Genotypes and Phenotypes of Gram‐Positive Cocci Using Long Short‐Term Memory Raman Spectra Methods

open access: yesAdvanced Intelligent Systems, Volume 5, Issue 4, April 2023., 2023
Herein, a novel method that used artificial intelligence to analyze biological Raman spectra to identify microbes and their antimicrobial resistance at both genotype and phenotype levels is developed. The novel method exhibits higher level of accuracy than those obtained using the machine learning algorithms.
Jiayue Lu   +7 more
wiley   +1 more source

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