Frontiers in Sustainable Food Systems, 2023 IntroductionThe presence of linezolid-resistant enterococci found in animal-derived food has attracted attention for possible transmission to human-derived enterococci through the food chain.
Juan Ni +11 more
doaj +2 more sources
Detection of the novel optrA gene among linezolid-resistant enterococci in Barcelona, Spain [PDF]
Microbial Drug Resistance, 2019 The purpose of this study was to describe the presence of the novel optrA gene among clinical isolates of enterococci in a Spanish teaching hospital (May 2016-April 2017). optrA and cfr genes were screened by PCR in all isolates showing linezolid minimal
Ardanuy Tisaire, María Carmen +6 more
core +4 more sources
Oxazolidinone resistance-associated genes cfr and optrA in MDR CoNS from healthy pigs in Italy [PDF]
JAC-Antimicrobial Resistance, 2022 BACKGROUND: Oxazolidinones are relatively novel antibiotics used exclusively in human medicine as last resort drugs for resistant pathogens like MRSA, vancomycin-resistant enterococci and penicillin-resistant Streptococcus pneumoniae.
Bonvegna, Miryam +2 more
core +5 more sources
Antibiotics, 2023 This study was performed to investigate the presence and characteristics of the oxazolidinone resistance genes optrA and cfr(D) in Streptococcus parasuis.
Ning Han +6 more
doaj +3 more sources
Genomic and clinical characterization of linezolid resistance in Enterococcus species from cancer patients in China [PDF]
BMC Infectious DiseasesBackground Immunocompromised cancer patients represent a susceptible population for enterococcal infections. While linezolid remains the primary therapeutic option for vancomycin-resistant Enterococcus (VRE) infections, the emergence of linezolid ...
Qun Wang +5 more
doaj +2 more sources
Molecular Epidemiology and Genetic Context of optrA-Carrying Linezolid-Resistant Enterococci from Humans and Animals in South Korea [PDF]
AntibioticsObjectives: Linezolid resistance among Enterococcus species poses a growing clinical and public health concern, especially due to the dissemination of transferable resistance genes, such as optrA.
Younggwon On +3 more
doaj +2 more sources
Prevalence and genetic diversity of optrA-positive enterococci isolated from patients in an anorectal surgery ward of a Chinese hospital [PDF]
Frontiers in MicrobiologyLinezolid-resistant enterococci have increased in recent years due to the worldwide spread of acquired resistance genes (cfr, optrA, and poxtA) in clinical, animal, and environmental settings.
Yuanyuan Li +7 more
doaj +2 more sources
Molecular Epidemiology and Horizontal Transfer Mechanism of optrA-Carrying Linezolid-Resistant Enterococcus faecalis [PDF]
Polish Journal of MicrobiologyThe aim of this work was to provide a theoretical and scientific basis for the treatment, prevention, and control of clinical drug-resistant bacterial infections by studying the molecular epidemiology and horizontal transfer mechanism of optrA-carrying ...
Yang Peini +6 more
doaj +2 more sources
Genetic Characterization of a Linezolid- and Penicillin-Resistant <i>Enterococcus hirae</i> Isolate Co-Harboring <i>poxtA</i> and <i>pbp5fm</i>. [PDF]
Transbound Emerg DisLinezolid and penicillin are critical for treating multidrug resistant (MDR) Gram‐positive infections, but the emergence of resistance to both seriously threatens public health. Here, we first report the cocarrying poxtA (oxazolidinone resistance) and pbp5fm (β‐lactam resistance) genes by the plasmid in a strain of Enterococcus hirae HDC14‐2 derived ...
Huang J +6 more
europepmc +2 more sources
Journal of Global Antimicrobial ResistanceObjectives: Linezolid is a last-resort antimicrobial in human clinical settings to treat multidrug-resistant Gram-positive bacterial infections. Mobile linezolid resistance genes (optrA, poxtA, and cfr) have been detected in various sources worldwide ...
Akira Fukuda +3 more
doaj +3 more sources