Results 21 to 30 of about 2,522,619 (179)

Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm [PDF]

Journal of Global Antimicrobial Resistance, 2020
Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Susana Sanz, Carmen Olarte, Inga Eichhorn, Stefan Schwarz, Carmen Torres   +7 more
doaj   +2 more sources

Nationwide Surveillance of Novel Oxazolidinone Resistance Gene optrA in Enterococcus Isolates in China from 2004 to 2014 [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACT A total of 2,201 nonduplicate enterococcal isolates collected from 29 hospitals in 23 cities in China between 2004 and 2014 were screened for the oxazolidinone resistance gene optrA ; 45 isolates (2.0%) were optrA positive with 11 OptrA variants identified.
Lanqing, Cui, Yang, Wang, Yuan, Lv, Shan, Wang, Yunjia, Song, Yun, Li, Jian, Liu, Feng, Xue, Weiwei, Yang, Jia, Zhang   +9 more
openaire   +3 more sources

Global dissemination of optrA-mediated linezolid resistance in enterococci [PDF]

J Antimicrob Chemother
Objectives: Acquired resistance to last-line linezolid has emerged in Enterococcus spp. and can be conferred by the optrA gene. Here, we study the global genomic context of optrA in E. faecalis and E.
Howden, B.P., Beh, J.Q., Webb, J.R., Connor, C.H.   +3 more
core   +2 more sources

Environmental occurrence of optrA-mediated linezolid resistance in Enterococcus isolates and genomic insights into Enterococcus faecium ST54 co-harboring optrA, poxtA, and cfr(D) genes [PDF]

World Journal of Microbiology and Biotechnology
Abstract Linezolid-resistant Enterococcus species have emerged worldwide, with resistance mainly driven by plasmid-borne optrA , poxtA , and cfr genes ...
Dos Santos, Lucas David Rodrigues, Furlan, João Pedro Rueda, da Silva Rosa, Rafael, Ramos, Micaela Santana, Gervasoni, Letícia Franco, Savazzi, Eduardo Angelino, Nogueira, Teresa, Stehling, Eliana Guedes   +7 more
openaire   +4 more sources

Genetic environment of the transferable oxazolidinone/phenicol resistance geneoptrAinEnterococcus faecalisisolates of human and animal origin [PDF]

Journal of Antimicrobial Chemotherapy, 2016
Aim of this study was to analyse 17 non-related Enterococcus faecalis isolates of human and animal origin for the genetic environment of the novel oxazolidinone/phenicol resistance gene optrA.WGS and de novo assembly were conducted to analyse the flanking sequences of the optrA gene in the 17 E. faecalis isolates.
Tao, He, Yingbo, Shen, Stefan, Schwarz, Jiachang, Cai, Yuan, Lv, Jun, Li, Andrea T, Feßler, Rong, Zhang, Congming, Wu, Jianzhong, Shen, Yang, Wang   +10 more
openaire   +3 more sources

Detection of the optrA Gene Among Polyclonal Linezolid-Susceptible Isolates of Enterococcus faecalis Recovered from Community Patients

Microbial Drug Resistance, 2022
Dispersion of transferable oxazolidinone resistance genes among enterococci poses a serious problem to human health. Prompt detection of bacteria carrying these genes is crucial to avoid their spread to multidrug-resistant bacteria.
Rodríguez-Lucas, Carlos, Fernández, Javier, Vázquez Sánchez, Xenia, Toro, María de, Ladero Losada, Víctor Manuel, Fuster, Carlos, Rodicio, Rosaura, Rodicio, M. Rosario   +7 more
openaire   +4 more sources

Prevalence and genetic diversity of optrA-positive enterococci isolated from patients in an anorectal surgery ward of a Chinese hospital [PDF]

Frontiers in Microbiology
Linezolid-resistant enterococci have increased in recent years due to the worldwide spread of acquired resistance genes (cfr, optrA, and poxtA) in clinical, animal, and environmental settings.
Yuanyuan Li, Tao Jiang, Jianfeng Mao, Fangyi Xu, Rong Zhang, Jing Yan, Jiachang Cai, Yanjun Xie   +7 more
doaj   +2 more sources

Co-location of the oxazolidinone resistance genesoptrAandcfron a multiresistance plasmid fromStaphylococcus sciuri [PDF]

Journal of Antimicrobial Chemotherapy, 2016
To identify and characterize the oxazolidinone/phenicol resistance gene optrA in Staphylococcus isolates.Fifty porcine staphylococci with florfenicol MICs of ≥16 mg/L were screened by PCR for the presence of the optrA gene. Transferability of optrA was examined by transformation and conjugation.
Dexi, Li, Yang, Wang, Stefan, Schwarz, Jiachang, Cai, Run, Fan, Jun, Li, Andrea T, Feßler, Rong, Zhang, Congming, Wu, Jianzhong, Shen   +9 more
openaire   +3 more sources

First detection of an optrA-positive, linezolid-resistant ST16 Enterococcus faecalis from human in Greece

New Microbes and New Infections, 2019
Until now, in Greece, the resistance of enterococci to linezolid was associated with mutations of domain V of 23S ribosomal RNA (G2576T). Here we report the first linezolid-resistant optrA-positive Enterococcus faecalis sequence type (ST) 16 isolated ...
K. Tsilipounidaki, A. Gerontopoulos, C. Papagiannitsis, E. Petinaki   +3 more
doaj   +2 more sources

Transferable optrA-mediated linezolid resistance in enterococci from high-altitude river sediments of Gilgit-Baltistan, Pakistan [PDF]

Applied and Environmental Microbiology
Environmental dissemination of antimicrobial resistance is a growing global concern. This study investigated the occurrence, genetic context, and mobility of the oxazolidinone resistance genes in enterococci isolated from high-altitude river sediments in
Serena Simoni, Andrea Brenciani, Alessandra Di Gregorio, Francesca Romana Massacci, Lucilla Cucco, Maisoor Ahmed Nafees, Saif Ud Din, Nelofar Hanif, Stefania Gorbi, Francesco Regoli, Eleonora Giovanetti, Carla Vignaroli   +11 more
doaj   +2 more sources