Results 21 to 30 of about 1,674 (204)

Emergence of linezolid-resistant Enterococcus cecorum clade F harboring optrA/fexA causing enterococcal spondylitis in commercial broilers in China [PDF]

BMC Microbiology
Background Enterococcus cecorum, long regarded as a commensal bacterium in the avian gut, has recently emerged as a significant pathogen causing enterococcal spondylitis.
Fanrun Meng, Defang Zhou, Ruiqi Li, Feng Lang, Bin Xiang, Liangyu Yang, Ziqiang Cheng   +6 more
doaj   +2 more sources

Coexistence of the Oxazolidinone Resistance–Associated Genes cfr and optrA in Enterococcus faecalis From a Healthy Piglet in Brazil [PDF]

Frontiers in Public Health, 2020
Oxazolidinones are one of the most important antimicrobials potentially active against glycopeptide- and β-lactam-resistant Gram-positive pathogens.
Lara M. Almeida, Lara M. Almeida, Anthony Gaca, Paulo M. Bispo, François Lebreton, Jose T. Saavedra, Rafael A. Silva, Irinaldo D. Basílio-Júnior, Felipe M. Zorzi, Pedro H. Filsner, Andrea M. Moreno, Michael S. Gilmore   +11 more
doaj   +3 more sources

The prevalence of optrA-carrying Enterococci in the vaginal micro-ecology of pregnant women in late pregnancy [PDF]

Microbiology Spectrum
The colonization of Enterococcus in the female vagina leads to neonatal and pediatric enterococcal septicemia. Linezolid (LZD) is a kind of mainstream drug for treating multidrug-resistant Gram-positive infections.
Yanjun Xie, Fangyi Xu, Huali Dong, Jianfeng Mao, Chuanling Zhang   +4 more
doaj   +2 more sources

Emergence of OptrA Gene Mediated Linezolid Resistance among Enterococcus Faecium: A Pilot Study from a Tertiary Care Hospital, India. [PDF]

Int J Mol Cell Med, 2023
E. faecium is the third most common cause of nosocomial infections. Linezolid (LNZ) is a reserve antibiotic recommended for infections caused by vancomycin resistant E. faecium (VREfm).  The aim of the present study was to investigate the prevalence of optrA gene among linezolid resistant E. faecium (LREfm) and to study the molecular epidemiology using
Rani V, Prakash A, Mannan MA, Das P, Haridas H, Gaindaa R.   +5 more
europepmc   +3 more sources

Presence of the optrA Gene in Methicillin-Resistant Staphylococcus sciuri of Porcine Origin. [PDF]

Antimicrob Agents Chemother, 2016
ABSTRACT A total of 57 methicillin-resistant Staphylococcus aureus (MRSA) isolates and 475 methicillin-resistant coagulase-negative staphylococci (MRCoNS) collected from pigs in the Guangdong province of China in 2014 were investigated for the presence of the novel oxazolidinone-phenicol resistance gene
Fan R, Li D, Wang Y, He T, Feßler AT, Schwarz S, Wu C.   +6 more
europepmc   +4 more sources

Characterization of multiresistance gene optrA in Bacillus subtillis from China. [PDF]

J Antimicrob Chemother
Che Y, Jiang J, Wu R, Wang L, Wu X, Chen Q, Chen R, Zhou L.   +7 more
europepmc   +3 more sources

An Optimized Screening Approach for the Oxazolidinone Resistance Gene optrA Yielded a Higher Fecal Carriage Rate among Healthy Individuals in Hangzhou, China

Microbiology Spectrum, 2022
The linezolid resistance mediated by optrA has exhibited an increasing trend among Gram-positive bacteria, which greatly limits the treatment options for severe bacterial infections.
Weiyi Shen, Yonglu Huang, Jiachang Cai
doaj   +1 more source

Various Mobile Genetic Elements Involved in the Dissemination of the Phenicol-Oxazolidinone Resistance Gene optrA in the Zoonotic Pathogen Streptococcus suis: a Nonignorable Risk to Public Health

Microbiology Spectrum, 2023
The rapid increase of phenicol-oxazolidinone (PhO) resistance in Streptococcus suis due to transferable resistance gene optrA is a matter of concern. However, genetic mechanisms for the dissemination of the optrA gene remain to be discovered.
Xingyang Dai, Junjie Sun, Boqin Zhu, Mingsiyi Lv, Liye Chen, Li Chen, Xiaoming Wang, Jinhu Huang, Liping Wang   +8 more
doaj   +1 more source

Commentary: Nationwide Surveillance of Novel Oxazolidinone Resistance Gene optrA in Enterococcus Isolates in China from 2004 to 2014 [PDF]

Frontiers in Microbiology, 2017
Gianluca Morroni, Andrea Brenciani, Serena Simoni, Carla Vignaroli, Marina Mingoia, Eleonora Giovanetti   +5 more
doaj   +3 more sources

Genomic insights of optrA-carrying linezolid-resistant Enterococcus faecium using hybrid assembly: first report from India

Journal of Global Antimicrobial Resistance, 2021
: Objectives: Linezolid resistance in Enterococcus faecium is emerging worldwide. In this study, we aimed to characterise two linezolid-resistant E. faecium isolates using whole-genome sequencing.
Yamuna Devi Bakthavatchalam, Karthick Vasudevan, Priyanka Babu, Ayyan Raj Neeravi, Vignesh Narasiman, Balaji Veeraraghavan   +5 more
doaj   +1 more source