Results 11 to 20 of about 2,970 (183)

Molecular Epidemiology and Horizontal Transfer Mechanism of optrA-Carrying Linezolid-Resistant Enterococcus faecalis. [PDF]

Pol J Microbiol
The aim of this work was to provide a theoretical and scientific basis for the treatment, prevention, and control of clinical drug-resistant bacterial infections by studying the molecular epidemiology and horizontal transfer mechanism of optrA-carrying ...
Yang P, Li J, Lv M, He P, Song G, Shan B, Yang X.   +6 more
europepmc   +4 more sources

Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentina

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The aim of this study was to characterize the first 14 optrA-carrying linezolid resistant E. faecalis clinical isolates recovered in seven Argentinian hospitals between 2016 and 2021.
Paula Gagetti, Diego Faccone, Paola Ceriana, Celeste Lucero, Alejandra Menocal, Grupo LRE Argentina, Alejandra Corso   +6 more
doaj   +5 more sources

Molecular characteristics of optrA-carrying Enterococcus faecalis from chicken meat in South Korea

Poultry Science, 2020
The purpose of this study was to identify the genetic environment of optrA gene in linezolid (LZD)-resistant Enterococcus faecalis from chicken meat and to describe the probable mechanism of dissemination of the optrA gene through plasmid or chromosomal ...
Sunghyun Yoon, Se Hyun Son, Yeong Bin Kim, Kwang Won Seo, Young Ju Lee   +4 more
doaj   +3 more sources

Characterization and comparative genomics analysis of RepA_N multi-resistance plasmids carrying optrA from Enterococcus faecalis

Frontiers in Microbiology, 2023
IntroductionThis research aimed to investigate the antibiotic resistance of Enterococcus faecalis from swine farms in Zhejiang Province and the prevalence and transmission mechanism of oxazolidone resistance gene optrA.MethodA total of 226 Enterococcus ...
Enbao Zhang, Shuaizhou Zong, Wei Zhou, Jinzhi Zhou, Jianzhong Han, Daofeng Qu   +5 more
doaj   +3 more sources

Genome characteristics of the optrA-positive Clostridium perfringens strain QHY-2 carrying a novel plasmid type

mSystems, 2023
Clostridium perfringens is a bacterial species of importance to both public and animal health. The gene optrA is the first gene that confers resistance to the tedizolid, a last-resort antimicrobial agent in human medicine.
Ke Wu, Zhe Li, Mingjin Fang, Yuan Yuan, Edward M. Fox, Yingqiu Liu, Ruichao Li, Li Bai, Wen Zhang, Wei-Min Zhang, Qi Yang, Lingling Chang, Pu Li, Xinglong Wang, Juan Wang, Zengqi Yang   +15 more
doaj   +3 more sources

Transmission of linezolid-resistant Enterococcus isolates carrying optrA and poxtA genes in slaughterhouses

Frontiers in Sustainable Food Systems, 2023
IntroductionThe presence of linezolid-resistant enterococci found in animal-derived food has attracted attention for possible transmission to human-derived enterococci through the food chain.
Juan Ni, Juan Ni, Xiaoqian Long, Xiaoqian Long, Mengmeng Wang, Jiangang Ma, Yangying Sun, Wen Wang, Min Yue, Hua Yang, Daodong Pan, Biao Tang   +11 more
doaj   +2 more sources

First detection of an optrA-positive, linezolid-resistant ST16 Enterococcus faecalis from human in Greece

New Microbes and New Infections, 2019
Until now, in Greece, the resistance of enterococci to linezolid was associated with mutations of domain V of 23S ribosomal RNA (G2576T). Here we report the first linezolid-resistant optrA-positive Enterococcus faecalis sequence type (ST) 16 isolated ...
K. Tsilipounidaki, A. Gerontopoulos, C. Papagiannitsis, E. Petinaki   +3 more
doaj   +3 more sources

Complete genome sequence of optrA-carrying Enterococcus faecalis isolated from open pus in a Japanese patient

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The occurrence of linezolid resistance in enterococci has recently increased. Here, we report the genomic characterization of Enterococcus faecalis strain JARB-HU0796—isolated from the open pus of a patient in Hiroshima, Japan—which shows ...
Takaya Segawa, Junzo Hisatsune, Kasumi Ishida-Kuroki, Yo Sugawara, Kanako Masuda, Kayoko Tadera, Seiya Kashiyama, Michiya Yokozaki, Mi Nguyen-Tra Le, Miki Kawada-Matsuo, Hiroki Ohge, Hitoshi Komatsuzawa, Motoyuki Sugai   +12 more
doaj   +3 more sources

Emergence of linezolid-resistant Enterococcus cecorum clade F harboring optrA/fexA causing enterococcal spondylitis in commercial broilers in China. [PDF]

BMC Microbiol
Background Enterococcus cecorum, long regarded as a commensal bacterium in the avian gut, has recently emerged as a significant pathogen causing enterococcal spondylitis.
Meng F, Zhou D, Li R, Lang F, Xiang B, Yang L, Cheng Z.   +6 more
europepmc   +2 more sources

Identification of the Phenicol Efflux Gene <i>fexB</i> and Its Co-Occurrence With the Oxazolidinone/Phenicol Resistance Gene <i>optrA</i> in Avian <i>Campylobacter jejuni</i> Isolates From Tunisia. [PDF]

Int J Microbiol
Background Campylobacter jejuni, a major foodborne and zoonotic pathogen linked to poultry, is showing rising resistance to last‐resort antimicrobials like oxazolidinones and phenicols. Such resistance threatens both animal and human health. Its ability to acquire genes from gram‐positive bacteria highlights the need for surveillance in avian ...
Gharbi M, Hamdi C, Abbas MAS, Hamrouni S, Maaroufi A.   +4 more
europepmc   +2 more sources