Results 21 to 30 of about 973 (111)

Molecular characteristics of optrA-carrying Enterococcus faecalis from chicken meat in South Korea

Poultry Science, 2020
The purpose of this study was to identify the genetic environment of optrA gene in linezolid (LZD)-resistant Enterococcus faecalis from chicken meat and to describe the probable mechanism of dissemination of the optrA gene through plasmid or chromosomal ...
Sunghyun Yoon, Se Hyun Son, Yeong Bin Kim, Kwang Won Seo, Young Ju Lee   +4 more
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Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus

Molecules, 2018
The optrA gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of optrA and whether it involves antibiotic efflux or
Yingyu Wang, Xiaowei Li, Yang Wang, Stefan Schwarz, Jianzhong Shen, Xi Xia   +5 more
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Oxazolidinone resistance genes in florfenicol-resistant enterococci from beef cattle and veal calves at slaughter

Frontiers in Microbiology, 2023
BackgroundLinezolid is a critically important oxazolidinone antibiotic used in human medicine. Although linezolid is not licensed for use in food-producing animals, the use of florfenicol in veterinary medicine co-selects for oxazolidinone resistance ...
Magdalena Nüesch-Inderbinen, Michael Biggel, Adrian Haussmann, Andrea Treier, Lore Heyvaert, Nicole Cernela, Roger Stephan   +6 more
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Prevalence and genetic diversity of optrA-positive enterococci isolated from patients in an anorectal surgery ward of a Chinese hospital

Frontiers in Microbiology
Linezolid-resistant enterococci have increased in recent years due to the worldwide spread of acquired resistance genes (cfr, optrA, and poxtA) in clinical, animal, and environmental settings.
Yuanyuan Li, Tao Jiang, Jianfeng Mao, Fangyi Xu, Rong Zhang, Jing Yan, Jiachang Cai, Yanjun Xie   +7 more
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High prevalence and plasmidome diversity of optrA-positive enterococci in a Shenzhen community, China

Frontiers in Microbiology
BackgroundThe emergence of optrA, which can confer resistance to phenicols and oxazolidinones in Enterococcus spp., poses a growing public health threat.Methods102 optrA-positive enterococci (OPEs) including various species were isolated from feces of ...
Yulin Fu, Zhaoju Deng, Yingbo Shen, Weizhou Wei, Qiumei Xiang, Zhiyang Liu, Kunning Hanf, Suli Huang, Suli Huang, Zexun Lv, Tingting Cao, Changfeng Peng, Rong Zhang, Xuan Zou, Jianzhong Shen, Stefan Schwarz, Stefan Schwarz, Stefan Schwarz, Yang Wang, Dejun Liu, Ziquan Lv, Yuebin Ke   +21 more
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Detection of Genes Related to Linezolid Resistance (poxtA, cfr, and optrA) in Clinical Isolates of Enterococcus spp. from Humans: A First Report from Iran

Advanced Biomedical Research, 2023
Background: Enterococci may develop resistance to linezolid through chromosomal mutations that involve specific linezolid resistance genes, such as cfr, optrA, and poxtA.
Majid Torabi, Jamshid Faghri, Farkhondeh Poursina   +2 more
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Emergence of optrA-Mediated Linezolid Resistance in Enterococcus faecium: A Molecular Investigation in a Tertiary Hospital of Southwest China from 2014–2018

Infection and Drug Resistance, 2022
Miao Yi,1 Jiaqi Zou,2 Jinxin Zhao,1 Yu Tang,3 Yaling Yuan,1 Bingxue Yang,1 Jinzhu Huang,1 Peiwen Xia,1 Yun Xia1 1Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China ...
Yi M, Zou J, Zhao J, Tang Y, Yuan Y, Yang B, Huang J, Xia P, Xia Y   +8 more
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Characterization of a Multiresistance Plasmid Carrying the optrA and cfr Resistance Genes From an Enterococcus faecium Clinical Isolate

Frontiers in Microbiology, 2018
Enterococcus faecium E35048, a bloodstream isolate from Italy, was the first strain where the oxazolidinone resistance gene optrA was detected outside China. The strain was also positive for the oxazolidinone resistance gene cfr.
Gianluca Morroni, Andrea Brenciani, Alberto Antonelli, Marco Maria D’Andrea, Marco Maria D’Andrea, Vincenzo Di Pilato, Simona Fioriti, Marina Mingoia, Carla Vignaroli, Oscar Cirioni, Francesca Biavasco, Pietro E. Varaldo, Gian Maria Rossolini, Gian Maria Rossolini, Eleonora Giovanetti   +14 more
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Sentinel Surveillance Reveals Emerging Daptomycin-Resistant ST736 Enterococcus faecium and Multiple Mechanisms of Linezolid Resistance in Enterococci in the United States

Frontiers in Microbiology, 2022
Enterococcus faecalis and faecium with resistance to daptomycin and/or linezolid are emerging globally. We present the genomic characterization of daptomycin- and linezolid-resistant E. faecalis and E. faecium surveillance isolates from the United States,
Amy S. Gargis, Lori M. Spicer, Lori M. Spicer, Alyssa G. Kent, Alyssa G. Kent, Wenming Zhu, Davina Campbell, Gillian McAllister, Thomas O. Ewing, Thomas O. Ewing, Valerie Albrecht, Valerie A. Stevens, Mili Sheth, Jasmine Padilla, Jasmine Padilla, Dhwani Batra, J. Kristie Johnson, Alison Laufer Halpin, J. Kamile Rasheed, Christopher A. Elkins, Maria Karlsson, Joseph D. Lutgring   +21 more
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Molecular Investigations of Linezolid Resistance in Enterococci OptrA Variants from a Hospital in Shanghai

Infection and Drug Resistance, 2020
Pei Li, Yang Yang, Li Ding, Xiaogang Xu, Dongfang Lin Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Dongfang Lin Tel/ Fax +86-21-52888193Email lindongfang@fudan.edu.cnPurpose: The ...
Li P, Yang Y, Ding L, Xu X, Lin D
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