Results 21 to 30 of about 2,970 (183)

Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm

Journal of Global Antimicrobial Resistance, 2020
Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Susana Sanz, Carmen Olarte, Inga Eichhorn, Stefan Schwarz, Carmen Torres   +7 more
doaj   +5 more sources

Transferable linezolid resistance genes (optrA and poxtA) in enterococci derived from livestock compost at Japanese farms

Journal of Global Antimicrobial Resistance
Objectives: Linezolid is a last-resort antimicrobial in human clinical settings to treat multidrug-resistant Gram-positive bacterial infections. Mobile linezolid resistance genes (optrA, poxtA, and cfr) have been detected in various sources worldwide ...
Akira Fukuda, Chie Nakajima, Yasuhiko Suzuki, Masaru Usui   +3 more
doaj   +3 more sources

Characterization of a Linezolid- and Vancomycin-Resistant Streptococcus suis Isolate That Harbors optrA and vanG Operons [PDF]

Frontiers in Microbiology, 2019
Linezolid and vancomycin are among the last-resort antimicrobial agents in the treatment of multidrug-resistant Gram-positive bacterial infections. Linezolid- and vancomycin-resistant (LVR) Gram-positive bacteria may pose severe threats to public health.
Fanshu Du, Xi Lv, Duan Duan, Liping Wang, Jinhu Huang   +4 more
doaj   +3 more sources

Characterization of multiresistance gene optrA in Bacillus subtillis from China. [PDF]

J Antimicrob Chemother
Che Y, Jiang J, Wu R, Wang L, Wu X, Chen Q, Chen R, Zhou L.   +7 more
europepmc   +3 more sources

Coexistence of optrA and fexA in Campylobacter

mSphere, 2021
Florfenicol is widely used for the treatment of respiratory infections and as a feed additive in food animal production. As a foodborne pathogen, Campylobacter is constantly exposed to florfenicol, and resistance to this antimicrobial agent has increased in recent years.
Biao Tang, Yao Wang, Yi Luo, Xue Zheng, Xiaoxia Qin, Hua Yang, Zhangqi Shen   +6 more
openaire   +3 more sources

Various Mobile Genetic Elements Involved in the Dissemination of the Phenicol-Oxazolidinone Resistance Gene optrA in the Zoonotic Pathogen Streptococcus suis: a Nonignorable Risk to Public Health

Microbiology Spectrum, 2023
The rapid increase of phenicol-oxazolidinone (PhO) resistance in Streptococcus suis due to transferable resistance gene optrA is a matter of concern. However, genetic mechanisms for the dissemination of the optrA gene remain to be discovered.
Xingyang Dai, Junjie Sun, Boqin Zhu, Mingsiyi Lv, Liye Chen, Li Chen, Xiaoming Wang, Jinhu Huang, Liping Wang   +8 more
doaj   +1 more source

An Optimized Screening Approach for the Oxazolidinone Resistance Gene optrA Yielded a Higher Fecal Carriage Rate among Healthy Individuals in Hangzhou, China

Microbiology Spectrum, 2022
The linezolid resistance mediated by optrA has exhibited an increasing trend among Gram-positive bacteria, which greatly limits the treatment options for severe bacterial infections.
Weiyi Shen, Yonglu Huang, Jiachang Cai
doaj   +1 more source

Vigilancia nacional de aislamientos clínicos de Enterococcus faecalis resistentes al linezolid portadores del gen optrA en Colombia, 2014-2019

Revista Panamericana de Salud Pública, 2020
Objetivo. Describir las características epidemiológicas, fenotípicas y genéticas de aislamientos clínicos portadores de optrA identificados en la vigilancia de resistencia antimicrobiana por el laboratorio del Instituto Nacional de Salud de Colombia ...
Sandra Yamile Saavedra, Johan Fabian Bernal, Efrain Montilla-Escudero, German Torres, Mabel Karina Rodríguez, Andrea Melissa Hidalgo, María Victoria Ovalle, Sandra Rivera, Enrique Perez-Gutierrez, Carolina Duarte   +9 more
doaj   +1 more source

Bile Carriage of optrA -Positive Enterococcus faecium in a Patient with Choledocholith

Microbiology Spectrum, 2023
Oxazolidinone are effective antimicrobial agents for the treatment of infections caused by multidrug-resistant Gram-positive bacteria, including vancomycin-resistant enterococci. The emergence and global spread of transferable oxazolidinone resistance genes such as optrA is worrisome. Enterococcus
Li Deng, Wendong Zhen, Jing Wang, Dachuan Lin   +3 more
openaire   +2 more sources

Comparative genomics of globaloptrA-carryingEnterococcus faecalisuncovers common genetic features and a chromosomal hotspot foroptrAacquisition

Microbial Genomics, 2019
AbstractLinezolid-resistantEnterococcus faecalis(LREfs) carryingoptrAare increasingly reported globally from multiple sources, but we still lack a comprehensive analysis of human and animaloptrA-LREfs strains. We investigated the phylogenetic structure, genetic content [antimicrobial resistance (AMR), virulence, prophages, plasmidome] andoptrA ...
Freitas, Ana R., Tedim, Ana P., Novais, Carla, Peixe, Luísa   +3 more
openaire   +4 more sources