Results 31 to 40 of about 973 (111)

Mechanisms of Linezolid Resistance Among Enterococci of Clinical Origin in Spain—Detection of optrA- and cfr(D)-Carrying E. faecalis

Microorganisms, 2020
The mechanisms of linezolid resistance among 13 E. faecalis and 6 E. faecium isolates, recovered from six Spanish hospitals during 2017–2018, were investigated.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Inga Eichhorn, José Manuel Azcona-Gutiérrez, Mar Olga Pérez-Moreno, Cristina Seral, Carmen Aspiroz, Carla Andrea Alonso, Luis Torres, Juan-Ignacio Alós, Stefan Schwarz, Carmen Torres   +12 more
doaj   +1 more source

Complete genome sequence of optrA-carrying Enterococcus faecalis isolated from open pus in a Japanese patient

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The occurrence of linezolid resistance in enterococci has recently increased. Here, we report the genomic characterization of Enterococcus faecalis strain JARB-HU0796—isolated from the open pus of a patient in Hiroshima, Japan—which shows ...
Takaya Segawa, Junzo Hisatsune, Kasumi Ishida-Kuroki, Yo Sugawara, Kanako Masuda, Kayoko Tadera, Seiya Kashiyama, Michiya Yokozaki, Mi Nguyen-Tra Le, Miki Kawada-Matsuo, Hiroki Ohge, Hitoshi Komatsuzawa, Motoyuki Sugai   +12 more
doaj   +1 more source

First detection of an optrA-positive, linezolid-resistant ST16 Enterococcus faecalis from human in Greece

New Microbes and New Infections, 2019
Until now, in Greece, the resistance of enterococci to linezolid was associated with mutations of domain V of 23S ribosomal RNA (G2576T). Here we report the first linezolid-resistant optrA-positive Enterococcus faecalis sequence type (ST) 16 isolated ...
K. Tsilipounidaki, A. Gerontopoulos, C. Papagiannitsis, E. Petinaki   +3 more
doaj   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Molecular characteristics of oxazolidinone resistance in enterococci from a multicenter study in China

BMC Microbiology, 2019
Background Linezolid-resistant enterococci pose great challenges in clinical practice. The aim of this study is to study the mechanisms underlying the resistance and genetic environment of antimicrobial resistance gene of linezolid-resistant enterococci.
Hongbin Chen, Xiaojuan Wang, Yuyao Yin, Shuguang Li, Yawei Zhang, Qi Wang, Hui Wang   +6 more
doaj   +1 more source

Antibiotic resistance mediated by site‐specific mutations in the multidrug efflux transporter CmeB of zoonotic pathogen Campylobacter

mLife, Volume 5, Issue 1, Page 83-98, February 2026.
Abstract The resistance‒nodulation‒division (RND) family of multidrug efflux transporters is widely distributed in Gram‐negative bacteria. Although their roles in mediating antibiotic resistance have been well known, our understanding of how they are altered to augment bacterial adaptation to antibiotic selection remains at an infancy stage.
Xiaolong Lin, Mengyu Zhao, Jianhong Gan, Haozheng Li, Min He, Fang Yang, Renqiao Wen, Tiejun Zhang, Quan Zhou, Ke Wu, Jinpeng Li, Chengyao Hou, Yang Cao, Hongning Wang, Yizhi Tang   +14 more
wiley   +1 more source

Characterization of a Novel Linezolid Resistance Gene optrA and Bacitracin Resistance Locus-Carrying Multiple Antibiotic Resistant Integrative and Conjugative Element ICESsu1112S in Streptococccus Suis

Microbiology Spectrum, 2022
Streptococcus suis strain 1112S was isolated from a diseased pig in a feedlot from Henan, China, in 2019. The isolate harbored a linezolid resistance gene optrA.
Yingying Yang, Xiuhua Kuang, Rong-jia Han, Ya-jun Zhai, Dan-dan He, Jin-feng Zhao, Jian-hua Liu, Gong-zheng Hu   +7 more
doaj   +1 more source

Coexistence of the Oxazolidinone Resistance–Associated Genes cfr and optrA in Enterococcus faecalis From a Healthy Piglet in Brazil

Frontiers in Public Health, 2020
Oxazolidinones are one of the most important antimicrobials potentially active against glycopeptide- and β-lactam-resistant Gram-positive pathogens.
Lara M. Almeida, Lara M. Almeida, Anthony Gaca, Paulo M. Bispo, François Lebreton, Jose T. Saavedra, Rafael A. Silva, Irinaldo D. Basílio-Júnior, Felipe M. Zorzi, Pedro H. Filsner, Andrea M. Moreno, Michael S. Gilmore   +11 more
doaj   +1 more source

Mechanistic Landscape and Farm to Fork Control Strategies for Streptococcus suis: An Emerging Foodborne Threat

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis (S. suis) is an emerging zoonotic agent that now rivals classical food‐borne pathogens in its global clinical burden of meningitis and septic shock. Recent epidemiological syntheses covering more than 30 countries now list over 1600 laboratory‐confirmed human cases with a pooled case‐fatality of about 12%, climbing beyond 18% in East
Wangyuan Yao, Meili Chen, Hongkai Ren, Qingqing Luo, Xuyuan Wang, Md. Akhtar, Zeeshan Ahmad Bhutta, Lianci Peng, Muhammad Yasir Nawaz, Mohammad Mehedi Hasan, Md. F. Kulyar, Rendong Fang, Zhong Peng   +12 more
wiley   +1 more source

A Triplex Real‐Time PCR Assay for Simultaneous Detection of Streptococcus suis, Glaesserella parasuis, and Actinobacillus pleuropneumoniae

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine respiratory disease complex is a multifactorial disease syndrome in swine in which bacterial pathogens play important roles. Among them, Streptococcus suis (SS), Glaesserella parasuis (GPS), and Actinobacillus pleuropneumoniae (APP) are important bacterial agents associated with respiratory disease in pigs, underscoring the need for a rapid ...
Hongkun Zhuang, Shun Kang, Chenxu Zheng, Zeren Peng, Jinlu Zhu, Zongfu Wu, Nanhua Chen   +6 more
wiley   +1 more source