Results 41 to 50 of about 973 (111)

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim   +2 more
wiley   +1 more source

Persistence of transferable oxazolidinone resistance genes in enterococcal isolates from a swine farm in China

open access: yesFrontiers in Microbiology, 2022
The appearance of transferable oxazolidinone resistance genes poses a major challenge to public health and environmental safety. These genes not only lead pathogenic bacteria to become resistant to linezolid but also reduce sensitivity to florfenicol ...
Zheren Huang   +6 more
doaj   +1 more source

Identification of Outer Membrane Vesicles as a New Vehicle Mediating Antibiotic Resistance Gene Transfer in Campylobacter

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT The emergence and worldwide dissemination of antibiotic resistance genes (ARGs) compromise antibiotic therapy and are a major public health crisis. Horizontal gene transfer (HGT) plays a major role in the spread of ARGs among bacterial pathogens.
Mengyu Zhao   +8 more
wiley   +1 more source

The prevalence of optrA-carrying Enterococci in the vaginal micro-ecology of pregnant women in late pregnancy

open access: yesMicrobiology Spectrum
The colonization of Enterococcus in the female vagina leads to neonatal and pediatric enterococcal septicemia. Linezolid (LZD) is a kind of mainstream drug for treating multidrug-resistant Gram-positive infections.
Yanjun Xie   +4 more
doaj   +1 more source

Antibiotic Resistance: A Genetic and Physiological Perspective

open access: yesMedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy   +9 more
wiley   +1 more source

Genomic epidemiology reveals multiple mechanisms of linezolid resistance in clinical enterococci in China

open access: yesAnnals of Clinical Microbiology and Antimicrobials
Background Infections caused by linezolid-resistant enterococci (LRE) are clinically difficult to treat and threaten patient health. However, there is a lack of studies on long time-span LRE strains in China.
Ziran Wang   +9 more
doaj   +1 more source

Emergence and Genomic Characterization of the First Reported optrA-Carrying Linezolid-Resistant Enterococci Isolated from Retail Broiler Meat in the United Arab Emirates

open access: yesFoods, 2022
The foodborne transfer of resistant genes from enterococci to humans and their tolerance to several commonly used antimicrobials are of growing concern worldwide.
Ihab Habib   +6 more
doaj   +1 more source

Spatio‐temporal characteristics of the gastrointestinal resistome in a cow‐to‐calf model and its environmental dissemination in a dairy production system

open access: yesiMeta, Volume 4, Issue 4, August 2025.
This study revealed spatio‐temporal characteristics of gastrointestinal resistome in a cow‐to‐calf model and the pattern of their spread to the environment and offspring in the dairy production system. The gastrointestinal tract of dairy cows is a natural reservoir of resistomes and distinguished by gut sites and regions.
Shuai Liu   +19 more
wiley   +1 more source

Molecular Epidemiology and Horizontal Transfer Mechanism of optrA-Carrying Linezolid-Resistant Enterococcus faecalis

open access: yesPolish Journal of Microbiology
The aim of this work was to provide a theoretical and scientific basis for the treatment, prevention, and control of clinical drug-resistant bacterial infections by studying the molecular epidemiology and horizontal transfer mechanism of optrA-carrying ...
Yang Peini   +6 more
doaj   +1 more source

Comparative Genomic and Phylogenetic Analysis of Salmonella enterica Isolated From Donkey

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Salmonella is one of the most prevalent foodborne and zoonotic pathogens threatening global public health and food safety. Salmonella enterica subspecies enterica serovar Abortusequi (S. Abortusequi) is frequently reported as the etiological agent of equine abortion, septicemia, and polyarthritis.
Yuhui Tian   +7 more
wiley   +1 more source

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