Results 31 to 40 of about 832 (175)

Detection of poxtA2, a presumptive poxtA ancestor, in a plasmid from a linezolid-resistant enterococcus gallinarum isolate [PDF]

Antimicrobial Agents and Chemotherapy, 2021
The poxtA gene encodes a protein belonging to the F lineage of the ATP-binding cassette superfamily, which can protect the bacterial ribosome from some anti-ribosomal antibiotics, including oxazolidinones (1).….
Antonelli, A., Baccani, I., Bartoloni, A., Coppi, M., Maggio, T. D., Pilato, V. D., Revollo, C., Rossolini, G. M., Spinicci, M., Villagran, A. L.   +9 more
core   +3 more sources

Seasonal prevalence and antimicrobial resistance profiles in Enterococcus spp. identified from mussels farmed along the coasts of the Abruzzo region [PDF]

Italian Journal of Food Safety
The present study aimed to investigate the antimicrobial resistance (AMR) circulation through the different seasons in the Enterococcus genus isolated from mussels (Mytilus galloprovincialis) for human consumption and farmed along the coasts of the ...
Gianluigi Ferri, Vincenzo Olivieri, Chiara Di Vittori, Alberto Vergara   +3 more
doaj   +2 more sources

Genomic epidemiology reveals multiple mechanisms of linezolid resistance in clinical enterococci in China [PDF]

Annals of Clinical Microbiology and Antimicrobials
Background Infections caused by linezolid-resistant enterococci (LRE) are clinically difficult to treat and threaten patient health. However, there is a lack of studies on long time-span LRE strains in China.
Ziran Wang, Danping Liu, Jingjia Zhang, Lingli Liu, Zeming Zhang, Chang Liu, Songnian Hu, Linhuan Wu, Zilong He, Hongli Sun   +9 more
doaj   +2 more sources

Structural basis for PoxtA-mediated resistance to Phenicol and Oxazolidinone antibiotics [PDF]

, 2021
AbstractPoxtA and OptrA are ATP binding cassette (ABC) proteins of the F subtype (ABCF) that confer resistance to oxazolidinone, such as linezolid, and phenicol antibiotics, such as chloramphenicol. PoxtA/OptrA are often encoded on mobile genetic elements, facilitating their rapid spread amongst Gram-positive bacteria.
Caillan Crowe-McAuliffe, Victoriia Murina, Marje Kasari, Hiraku Takada, Kathryn Jane Turnbull, Yury S. Polikanov, Arnfinn Sundsfjord, Kristin Hegstad, Gemma C. Atkinson, Daniel N. Wilson, Vasili Hauryliuk   +10 more
openaire   +1 more source

Genetic features of the poxtA linezolid resistance gene in human enterococci from France

Journal of Antimicrobial Chemotherapy, 2021
Abstract Objectives To describe the prevalence of poxtA among clinical linezolid-resistant enterococci (LRE) collected in France from 2016 to 2020 and to extensively characterize its genetic supports and environments.
Loren Dejoies, Mohamed Sassi, Sacha Schutz, Julie Moreaux, Asma Zouari, Sophie Potrel, Anaïs Collet, Maxime Lecourt, Gabriel Auger, Vincent Cattoir   +9 more
openaire   +3 more sources

Faecal carriage of enterococci harbouring oxazolidinone resistance genes among healthy humans in the community in Switzerland [PDF]

, 2022
Objectives: This study aimed to investigate the faecal carriage of enterococci harbouring oxazolidinone resistance genes among healthy humans in Switzerland and to genetically characterize the isolates. Methods: A total of 399 stool samples from healthy
Biggel, Michael, Nüesch-Inderbinen, Magdalena, Stephan, Roger, Treier, Andrea, Zurfluh, Katrin   +4 more
core   +1 more source

Characterization of an MDR Lactobacillus salivarius isolate harbouring the phenicol-oxazolidinone-tetracycline resistance gene poxtA

Journal of Antimicrobial Chemotherapy, 2022
Abstract Objectives To characterize the oxazolidinone resistance gene poxtA in a Lactobacillus salivarius isolate of pig origin. Methods L.
Yao Zhu, Wenlin Yang, Stefan Schwarz, Qiu Xu, Qin Yang, Lingli Wang, Siguo Liu, Wanjiang Zhang   +7 more
openaire   +4 more sources

Genomic Characterization and Phylogenetic Analysis of Linezolid-Resistant Enterococcus from the Nostrils of Healthy Hosts Identifies Zoonotic Transmission. [PDF]

Curr Microbiol
Abdullahi IN, Lozano C, Zarazaga M, Latorre-Fernández J, Hallstrøm S, Rasmussen A, Stegger M, Torres C.   +7 more
europepmc   +3 more sources

Characterization of poxtA, a novel phenicol–oxazolidinone–tetracycline resistance gene from an MRSA of clinical origin [PDF]

Journal of Antimicrobial Chemotherapy, 2018
To characterize a novel phenicol-oxazolidinone-tetracycline resistance gene, named poxtA, identified in a previously described MRSA strain that was highly resistant to linezolid and also carried the cfr gene.The poxtA gene was identified by bioinformatic analysis of the whole genome sequence of Staphylococcus aureus AOUC-0915. The poxtA gene was cloned
Antonelli A., D'Andrea M. M., Brenciani A., Galeotti C. L., Morroni G., Pollini S., Varaldo P. E., Rossolini G. M.   +7 more
openaire   +4 more sources

High occurrence of Enterococcus faecalis, Enterococcus faecium, and Vagococcus lutrae harbouring oxazolidinone resistance genes in raw meat-based diets for companion animals – a public health issue, Switzerland, September 2018 to May 2020 [PDF]

, 2023
Introduction: Enterococci harbouring genes encoding resistance to florfenicol and the oxazolidinone antimicrobial linezolid have emerged among food-producing animals and meat thereof, but few studies have analysed their occurrence in raw meat-based diets
Biggel, Michael, Cernela, Nicole, Heyvaert, Lore, Nüesch-Inderbinen, Magdalena, Stephan, Roger, Treier, Andrea, Zurfluh, Katrin   +6 more
core   +1 more source