Results 11 to 20 of about 808,923 (313)
Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products
Pharmaceutics, 2020 Prodrugs are bioreversible, inactive drug derivatives, which have the ability to convert into a parent drug in the body. In the past, prodrugs were used as a last option; however, nowadays, prodrugs are considered already in the early stages of drug ...
Milica Markovic +2 more
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Antithrombotic Activity of Heparinoid G2 and Its Derivatives from the Clam Coelomactra antiquata
Marine Drugs, 2022 Clam heparinoid G2 (60.25 kDa) and its depolymerized derivatives DG1 (24.48 kDa) and DG2 (6.75 kDa) prepared from Coelomactra antiquata have been documented to have excellent fibrinolytic and anticoagulant activity.
Guanlan Chen +7 more
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Expression and Purification of a PEDV-Neutralizing Antibody and Its Functional Verification
Viruses, 2021 Porcine epidemic diarrhea virus (PEDV) is a highly infectious and pathogenic virus causing high morbidity and mortality, especially in newborn piglets. There remain problems with contemporary PEDV vaccines, in part because of the rapid variation of PEDV,
Wenshu Shi +6 more
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Biomolecules, 2022 In the sericulture and silk production industry, sericin is discharged in the degumming wastewater, resulting in a large amount of wasted natural protein and environmental pollution. This study investigated the effect of degraded sericin recovered by the
Zhen-Zhen Wei +2 more
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Human Vaccines & Immunotherapeutics, 2022 This study provides a snapshot of the current vaccine business ecosystem, including practices, challenges, beliefs, and expectations of vaccine providers.
S. Indu Rupassara +3 more
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Pathogens, 2022 Animal African trypanosomosis (AAT) leads to emaciation and low productivity in infected animals. Only six drugs are commercially available against AAT; they have severe side effects and face parasite resistance.
Keisuke Suganuma +7 more
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Applied Sciences, 2022 Sambucus nigra L., popularly known as elderberry, is renowned for its amazing therapeutic properties, as well as its uses as a food source, in nutraceuticals, and in traditional medicine.
Tiago Azevedo +17 more
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Intravenous Voriconazole after Toxic Oral Administration [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT In a male patient with rhinocerebral invasive aspergillosis, prolonged high-dosage oral administration of voriconazole led to hepatotoxicity combined with a severe cutaneous reaction while intravenous administration in the same patient did not.
Alffenaar, J.W.C. +5 more
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Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium
Marine Drugs, 2022 The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential
Ji-Su Ahn +16 more
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Oral Administration of Bacitracin
Experimental Biology and Medicine, 1948 SummaryFrom the small series of animals receiving oral bacitracin, the following significant facts were obtained: 1. Fecal streptococci and spore forming anaerobes were greatly reduced in the intestine at a dosage between 2,000 and 10,000 u/kg per day. 2. Coliform organisms were little affected by bacitracin. 3.
G. C. Bond +3 more
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