Results 11 to 20 of about 799,860 (208)

Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products

open access: yesPharmaceutics, 2020
Prodrugs are bioreversible, inactive drug derivatives, which have the ability to convert into a parent drug in the body. In the past, prodrugs were used as a last option; however, nowadays, prodrugs are considered already in the early stages of drug ...
Milica Markovic   +2 more
doaj   +1 more source

Antithrombotic Activity of Heparinoid G2 and Its Derivatives from the Clam Coelomactra antiquata

open access: yesMarine Drugs, 2022
Clam heparinoid G2 (60.25 kDa) and its depolymerized derivatives DG1 (24.48 kDa) and DG2 (6.75 kDa) prepared from Coelomactra antiquata have been documented to have excellent fibrinolytic and anticoagulant activity.
Guanlan Chen   +7 more
doaj   +1 more source

Expression and Purification of a PEDV-Neutralizing Antibody and Its Functional Verification

open access: yesViruses, 2021
Porcine epidemic diarrhea virus (PEDV) is a highly infectious and pathogenic virus causing high morbidity and mortality, especially in newborn piglets. There remain problems with contemporary PEDV vaccines, in part because of the rapid variation of PEDV,
Wenshu Shi   +6 more
doaj   +1 more source

Oral Administration of Bacitracin

open access: yesExperimental Biology and Medicine, 1948
SummaryFrom the small series of animals receiving oral bacitracin, the following significant facts were obtained: 1. Fecal streptococci and spore forming anaerobes were greatly reduced in the intestine at a dosage between 2,000 and 10,000 u/kg per day. 2. Coliform organisms were little affected by bacitracin. 3.
G. C. Bond   +3 more
openaire   +2 more sources

GENERAL ANALGESIA BY ORAL ADMINISTRATION [PDF]

open access: yesBMJ, 1918
This report is in the nature of a preliminary communication based on animal experiments and a sufficient number of clinical cases to support the conclusions of the animal work. It will be seen that general analgesia in which there is loss of sensation, with or without loss of consciousness, can be established for otherwise painful dressings and for ...
J T, Gwathmey, H T, Karsner
openaire   +2 more sources

Investigation of the Repairing Effect and Mechanism of Oral Degraded Sericin on Liver Injury in Type II Diabetic Rats

open access: yesBiomolecules, 2022
In the sericulture and silk production industry, sericin is discharged in the degumming wastewater, resulting in a large amount of wasted natural protein and environmental pollution. This study investigated the effect of degraded sericin recovered by the
Zhen-Zhen Wei   +2 more
doaj   +1 more source

Challenges and opportunities in current vaccine technology and administration: A comprehensive survey examining oral vaccine potential in the United States

open access: yesHuman Vaccines & Immunotherapeutics, 2022
This study provides a snapshot of the current vaccine business ecosystem, including practices, challenges, beliefs, and expectations of vaccine providers.
S. Indu Rupassara   +3 more
doaj   +1 more source

Therapeutic Efficacy of Orally Administered Nitrofurantoin against Animal African Trypanosomosis Caused by Trypanosoma congolense Infection

open access: yesPathogens, 2022
Animal African trypanosomosis (AAT) leads to emaciation and low productivity in infected animals. Only six drugs are commercially available against AAT; they have severe side effects and face parasite resistance.
Keisuke Suganuma   +7 more
doaj   +1 more source

Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants

open access: yesApplied Sciences, 2022
Sambucus nigra L., popularly known as elderberry, is renowned for its amazing therapeutic properties, as well as its uses as a food source, in nutraceuticals, and in traditional medicine.
Tiago Azevedo   +17 more
doaj   +1 more source

Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium

open access: yesMarine Drugs, 2022
The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential
Ji-Su Ahn   +16 more
doaj   +1 more source

Home - About - Disclaimer - Privacy