Results 31 to 40 of about 5,189,653 (310)

Cocrystallization of Gefitinib Potentiate Single-Dose Oral Administration for Lung Tumor Eradication via Unbalancing the DNA Damage/Repair

open access: yesPharmaceutics, 2023
Gefitinib (GEF) is a clinical medication for the treatment of lung cancer targeting the epidermal growth factor receptor (EGFR). However, its efficacy is remarkably limited by low solubility and dissolution rates.
Muhammad Inam   +10 more
doaj   +1 more source

Recent Progress in Diatom Biosilica: A Natural Nanoporous Silica Material as Sustained Release Carrier

open access: yesPharmaceutics, 2023
A drug delivery system (DDS) is a useful technology that efficiently delivers a target drug to a patient’s specific diseased tissue with minimal side effects.
Hayeon Lim   +7 more
doaj   +1 more source

Comparison of Subjective Responses to Oral and Intravenous Alcohol Administration under Similar Systemic Exposures [PDF]

open access: yes, 2019
Objective To test whether an individual's subjective responses to alcohol are similar when the breath alcohol concentration (BrAC) trajectory resulting from oral administration is matched by intravenous administration.
Boes, Julian   +6 more
core   +1 more source

Micellisation Mechanism and Behaviour of Soluplus®–Furosemide Micelles: Preformulation Studies of an Oral Nanocarrier-Based System

open access: yesPharmaceuticals, 2019
: In this study, self-assembling Soluplus® micelles were examined for inherent properties. Through calorimetric analysis, the critical micelle concentration (CMC) could be determined at 25 and 37 °C, and the influence of three media (Milli-Q ...
Julia F. Alopaeus   +2 more
doaj   +1 more source

Expression and Purification of a PEDV-Neutralizing Antibody and Its Functional Verification

open access: yesViruses, 2021
Porcine epidemic diarrhea virus (PEDV) is a highly infectious and pathogenic virus causing high morbidity and mortality, especially in newborn piglets. There remain problems with contemporary PEDV vaccines, in part because of the rapid variation of PEDV,
Wenshu Shi   +6 more
doaj   +1 more source

Oral Administration of Salecan-Based Hydrogels for Controlled Insulin Delivery.

open access: yesJournal of Agricultural and Food Chemistry, 2018
We present an improved type of food gum (salecan) based hydrogels for oral delivery of insulin. Structural hydrogel formation was assessed with Fourier transform infrared spectroscopy, thermogravimetric analysis, and X-ray diffraction.
Xiaoliang Qi   +4 more
semanticscholar   +1 more source

Oral Administration of Peppermint in Wistar Albino Rats: Memory Boosting and Regaining [PDF]

open access: yes, 2013
The studies on peppermint aroma fluence on cognition are numerous. However the knowledge about oral consumption of peppermint and cognition was inadequate. Hence the present study was undertaken to find out the effect of oral administration of peppermint
Jasira, M. (M)   +2 more
core   +2 more sources

Repeated, low-dose oral esketamine in patients with treatment-resistant depression: pilot study

open access: yesBJPsych Open, 2022
Background Intravenous infusion of ketamine can produce rapid and large symptom reduction in patients with treatment-resistant depression (TRD) but presents major obstacles to clinical applicability, especially in community settings. Oral esketamine may
Sanne Y. Smith-Apeldoorn   +6 more
doaj   +1 more source

Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome

open access: yesMsphere, 2018
Increasing evidence suggest that alterations of the gut microbiome underlie metabolic disease pathology by modulating gut metabolite profiles. We have shown that orally administered Porphyromonas gingivalis, a representative periodontopathic bacterium ...
Tamotsu Kato   +7 more
semanticscholar   +1 more source

Orally Administered Halofuginone-Loaded TPGS Polymeric Micelles Against Triple-Negative Breast Cancer: Enhanced Absorption and Efficacy with Reduced Toxicity and Metastasis

open access: yesInternational Journal of Nanomedicine, 2022
Runan Zuo,1 Yan Zhang,1 Xiaorong Chen,1 Shiheng Hu,1 Xinhao Song,1 Xiuge Gao,1 Jiahao Gong,1 Hui Ji,1 Fengzhu Yang,1 Lin Peng,1 Kun Fang,2 Yingjun Lv,1 Junren Zhang,1 Shanxiang Jiang,1 Dawei Guo1 1Engineering Center of Innovative Veterinary Drugs, Center
Zuo R   +14 more
doaj  

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