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Oral Bioavailability of Monoclonal Antibody [PDF]
PharmaceuticsBackground/Objectives: Despite significant interest in the oral delivery of antibodies, the oral bioavailability of monoclonal antibodies (mAbs) is not known to date.
Ashwni Verma +2 more
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Strategies to Overcome Heparins’ Low Oral Bioavailability [PDF]
Pharmaceuticals, 2016 Even after a century, heparin is still the most effective anticoagulant available with few side effects. The poor oral absorption of heparins triggered the search for strategies to achieve oral bioavailability since this route has evident advantages over
Ana Rita Neves +3 more
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Oral Bioavailability Enhancement of Anti-Cancer Drugs Through Lipid Polymer Hybrid Nanoparticles [PDF]
PharmaceuticsCancer is considered as the second leading cause of death worldwide. Chemotherapy, radiotherapy, immunotherapy, and targeted drug delivery are the main treatment options for treating cancers. Chemotherapy drugs are either available for oral or parenteral
Saud Almawash
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Comparison of Solid Self-Nanoemulsifying Systems and Surface-Coated Microspheres: Improving Oral Bioavailability of Niclosamide [PDF]
International Journal of NanomedicineKyungho Baek,1 Mi Ran Woo,2 Fakhar ud Din,3 Yong Seok Choi,4 Myung Joo Kang,4 Jong Oh Kim,5 Han-Gon Choi,2 Sung Giu Jin1 1Department of Pharmaceutical Engineering, Dankook University, Cheonan, South Korea; 2College of Pharmacy, Hanyang University, Ansan,
Baek K +7 more
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Absorption and Bioavailability of Novel UltraShear Nanoemulsion of Cannabidiol in Rats
Medical Cannabis and Cannabinoids, 2023 Introduction: Cannabidiol (CBD) has several potential benefits and therapeutic uses, especially in pain, inflammation, and anxiety. CBD has high hydrophobicity and very low solubility in water.
Mahmoud A. ElSohly +2 more
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Systems biological approach of molecular descriptors connectivity: optimal descriptors for oral bioavailability prediction. [PDF]
PLoS ONE, 2012 Poor oral bioavailability is an important parameter accounting for the failure of the drug candidates. Approximately, 50% of developing drugs fail because of unfavorable oral bioavailability.
Shiek S S J Ahmed, V Ramakrishnan
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Journal of Ginseng Research, 2023 Panax ginseng Meyer is a traditional Chinese medicine that is widely used as tonic in Asia. The main pharmacologically active components of ginseng are the dammarane-type ginsenosides, which have been shown to have anti-cancer, anti-inflammatory ...
Qi-rui Hu +7 more
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Iraqi Journal of Pharmaceutical Sciences, 2023 Piperine, a crystalline alkaloid compound isolated from Piper nigrum, piper longum, and other types of piper, has had many fabulous pharmacological advantages for preventing and treating some specific diseases, such as analgesic, anti-inflammatory ...
Akhmad Kharis Nugroho +3 more
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Advances in Oral Drug Delivery Systems: Challenges and Opportunities
Pharmaceutics, 2023 The oral route is the most preferred route for systemic and local drug delivery. However, the oral drug delivery system faces the harsh physiological and physicochemical environment of the gastrointestinal tract, which limits the bioavailability and ...
Jie Lou +6 more
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Bioavailability of oral curcumin [PDF]
Canadian Medical Association Journal, 2019 In our research article, we conclude that the regimen of curcumin we tested exerted no beneficial pharmacodynamic effect on the outcomes we assessed in the setting of elective abdominal aortic aneurysm repair.[1][1] These findings advance knowledge. Dr.
Amit X, Garg +5 more
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