Results 11 to 20 of about 261,112 (210)
Iraqi Journal of Pharmaceutical Sciences, 2023 Piperine, a crystalline alkaloid compound isolated from Piper nigrum, piper longum, and other types of piper, has had many fabulous pharmacological advantages for preventing and treating some specific diseases, such as analgesic, anti-inflammatory ...
Akhmad Kharis Nugroho +3 more
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Bioavailability of oral curcumin [PDF]
Canadian Medical Association Journal, 2019 In our research article, we conclude that the regimen of curcumin we tested exerted no beneficial pharmacodynamic effect on the outcomes we assessed in the setting of elective abdominal aortic aneurysm repair.[1][1] These findings advance knowledge. Dr.
Amit X, Garg +5 more
openaire +2 more sources
Advances in Oral Drug Delivery Systems: Challenges and Opportunities
Pharmaceutics, 2023 The oral route is the most preferred route for systemic and local drug delivery. However, the oral drug delivery system faces the harsh physiological and physicochemical environment of the gastrointestinal tract, which limits the bioavailability and ...
Jie Lou +6 more
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Pharmacokinetics and bioavailability of oral ifosfamide [PDF]
Journal of Cancer Research and Clinical Oncology, 1986 The bioavailability of oral N,3-bis(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide (ifosfamide) (500-mg gelatine capsules) was investigated in 18 patients with bronchogenic carcinoma. Oral and intravenous (Holoxan) ifosfamide was applicated in a randomized sequence on days 1 and 3 at a dose of 1 g/m2 (n = 12) and 2 g/m2 (n = 6 ...
T, Wagner, P, Drings
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Pilot toxicokinetic study and absolute oral bioavailability of the Fusarium mycotoxin enniatin B1 in pigs [PDF]
Food and Chemical Toxicology, 2014 Mathias Devreese +2 more
exaly +3 more sources
Pharmaceutics, 2023 Background: Hydroxy-α-Sanshool (HAS) possesses various pharmacological properties, such as analgesia and regulating gastrointestinal function. However, the low oral bioavailability of HAS has limited its oral delivery in clinical application. Methods and
Fengming Tan +6 more
doaj +1 more source
Gap analysis of nickel bioaccessibility and bioavailability in different food matrices and its impact on the nickel exposure assessment [PDF]
, 2020 The metal nickel is well known to cause nickel allergy in sensitive humans by prolonged dermal contact to materials releasing (high) amounts of nickel. Oral nickel exposure via water and food intake is of potential concern.
Babaahmadifooladi, Mehrnoosh +3 more
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New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats
Pharmaceuticals, 2022 Liver fibrosis is challenging to treat because of the lack of effective agents worldwide. Recently, we have developed a novel compound, N-(3,4,5-trichlorophenyl)-2(3-nitrobenzenesulfonamido) benzamide referred to as IMB16-4.
Xia Niu +5 more
doaj +1 more source
Cyclosporine Absorption Following Orthotopic Liver Transplantation [PDF]
, 1986 Blood concentrations of cyclosporine were determined in adult and pediatric patients following orthotopic liver transplantation to quantitate cyclosporine blood clearance and oral absorption.
Beveridge +20 more
core +2 more sources
Cyclic peptide oral bioavailability: lessons from the past [PDF]
, 2016 Achieving high oral bioavailability for drugs is a key design objective in drug development. It is not surprising then that with the growing expectation of peptides as future drugs, there has also been an increasing interest in developing oral peptide ...
Craik, David J., Wang, Conan K.
core +1 more source