Results 51 to 60 of about 261,112 (210)

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition [PDF]

open access: yes, 2015
Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking.
Bordoni, Alessandra   +11 more
core   +4 more sources

Vitamin K as a diet supplement with impact in human health: current evidence in age-related idseases [PDF]

open access: yes, 2020
Vitamin K health benefits have been recently widely shown to extend beyond blood homeostasis and implicated in chronic low-grade inflammatory diseases such as cardiovascular disease, osteoarthritis, dementia, cognitive impairment, mobility disability ...
Araujo, Nuna C. P.   +3 more
core   +1 more source

Nanoemulsion-based delivery system for enhanced oral bioavailability and Caco-2 cell monolayers permeability of berberine hydrochloride

open access: yesDrug Delivery, 2017
Berberine hydrochloride (BBH) has a variety of pharmacological activities such as antitumor, antimicrobial, anti-inflammation, and reduce irritable bowel syndrome. However, poor stability and low oral bioavailability limited its usage.
Yong-Jiang Li   +6 more
doaj   +1 more source

Formulation of itraconazole nanococrystals and evaluation of their bioavailability in dogs [PDF]

open access: yes, 2014
The aim of the study is to increase the bioavailability of itraconazole (ITRA) using nanosized cocrystals prepared via wet milling of ITRA in combination with dicarboxylic acids.
Adriaensens, Peter   +7 more
core   +1 more source

Oral bioavailability of levamisole in goats

open access: yesJournal of Veterinary Pharmacology and Therapeutics, 2001
P. 439-442 Levamisole is a broad-spectrum anthelmitic available for veter­ inary medical use for over 30 years. It shows activity against a wide variety of gastrointestinal and pulmonary nematodes, and possesses an immunomodulating effect ...
Sahagún , Ana M.   +5 more
openaire   +4 more sources

Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity

open access: yesPharmaceutics, 2019
Ticagrelor (TGL), a P2Y12 receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and permeability, resulting in low oral bioavailability.
Gi-Ho Son   +8 more
doaj   +1 more source

Genetic programming in data mining for drug discovery [PDF]

open access: yes, 2004
Genetic programming (GP) is used to extract from rat oral bioavailability (OB) measurements simple, interpretable and predictive QSAR models which both generalise to rats and to marketed drugs in humans. Receiver Operating Characteristics (ROC) curves
Barrett, S.J., Langdon, W.B.
core   +2 more sources

Virtual screening for NS5B inhibitors of Hepatitis C virus [PDF]

open access: yes, 2012
Hepatitis C Virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at a risk of developing significant morbidity and mortality.
Achuthsankar S. Nair   +2 more
core   +2 more sources

Strategies to Enhance the Solubility and Bioavailability of Tocotrienols Using Self-Emulsifying Drug Delivery System

open access: yesPharmaceuticals, 2023
Tocotrienols have higher medicinal value, with multiple sources of evidence showing their biological properties as antioxidant, anti-inflammatory, and osteoprotective compounds.
Nur-Vaizura Mohamad
doaj   +1 more source

Delivery of the vitamin E compound tocotrienol to cancer cells [PDF]

open access: yes, 2011
Tocotrienol, a member of the vitamin E family of compounds, is currently receiving increased attention because of its highly promising anti-cancer effects.
Dufès, Christine
core  

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