Results 81 to 90 of about 261,112 (210)

Comparing the pharmacokinetics of GS-441524 after intravenous and oral administration of remdesivir in New Zealand cats with feline infectious peritonitis

Journal of Feline Medicine and Surgery
Objectives The aim of the study was to compare the pharmacokinetics of GS-441524 after intravenous (IV) and oral administration of compounded remdesivir (RDV) at 30 mg/kg, respectively, in cats with clinical feline infectious peritonitis (FIP) and to ...
Kelsey Ann Renner, Benjamin Kimble, Ryan Cattin, John S Munday, Sally Coggins   +4 more
doaj   +1 more source

Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]

, 2010
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna, Ashton, Michael, Björkman, Anders, Dahlström, Sabina, Färnert, Anna, Gil, Pedro, Hietala, Sofia Friberg, Lindegårdh, Niklas, Mårtensson, Andreas, Ngasala, Billy, Premji, Zul   +10 more
core   +4 more sources

Carotenoids - Effective Radical Scavengers for Healthy and Beautiful Skin [PDF]

, 2019
Free radicals are involved in various diseases and skin aging. To reduce and prevent this risk, our body produces antioxidants that can neutralize free radicals.
Darvin, Maxim E., Elpelt, Anja, Lademann, Jürgen, Lohan, Silke B., Meinke, Martina C.   +4 more
core   +1 more source

Chronic dietary intake of enniatin B in broiler chickens has low impact on intestinal morphometry and hepatic histology, and shows limited transfer to liver tissue [PDF]

, 2018
The Fusarium mycotoxin enniatin B (ENN B) is a so-called emerging mycotoxin frequently contaminating poultry feed. To investigate the impact of chronic ENN B exposure on animal health, broiler chickens were fed either a diet naturally contaminated with ...
Antonissen, Gunther, Croubels, Siska, Devreese, Mathias, Ducatelle, Richard, Fraeyman, Sophie, Rychlik, Michael   +5 more
core   +2 more sources

Impact of water hardness on oxytetracycline oral bioavailability in fed and fasted piglets

Veterinary Medicine and Science, 2019
Water hardness is a critical factor that affects oxytetracycline dissolution by chelation with cations. These interactions may lead to impaired dosing and consequently decrease absorption.
Julieta M. Decundo, Susana N. Diéguez, Guadalupe Martínez, Agustina Romanelli, María B. Fernández Paggi, Denisa S. Pérez Gaudio, Fabián A. Amanto, Alejandro L. Soraci   +7 more
doaj   +1 more source

Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge 

International Journal of Nanomedicine, 2015
Gelareh Arzani,1 Azadeh Haeri,1 Marjan Daeihamed,1 Hamid Bakhtiari-Kaboutaraki,1 Simin Dadashzadeh1,2 1Department of Pharmaceutics, Faculty of Pharmacy, 2Pharmaceutical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran ...
Arzani G, Haeri A, Daeihamed M, Bakhtiari-Kaboutaraki H, Dadashzadeh S   +4 more
doaj  

MIL-100(Fe)-Enabled Oral Delivery of Syringic Acid with Enhanced Pharmacokinetics

Pharmaceutics
Background/Objectives: Plant-derived bioactive compounds like syringic acid, a phenolic acid from the shikimic acid pathway, have shown potential against chronic diseases, including diabetes, cardiovascular disorders, cancer, and cerebral ischemia ...
Joshua H. Santos, Hannah Jean Victoriano, Mary Sepulveda, Hung-En Liu, Shierrie Mae N. Valencia, Rikkamae Zinca Marie L. Walde, Emelda A. Ongo, Chia-Her Lin   +7 more
doaj   +1 more source

Improved Oral Bioavailability Using a Solid Self-Microemulsifying Drug Delivery System Containing a Multicomponent Mixture Extracted from Salvia miltiorrhiza

Molecules, 2016
The active ingredients of salvia (dried root of Salvia miltiorrhiza) include both lipophilic (e.g., tanshinone IIA, tanshinone I, cryptotanshinone and dihydrotanshinone I) and hydrophilic (e.g., danshensu and salvianolic acid B) constituents.
Xiaolin Bi, Xuan Liu, Liuqing Di, Qiang Zu   +3 more
doaj   +1 more source

Ibrutinib oral suspension bioavailability and compatibility for optimal enteral administration route

Therapeutic Advances in Hematology
Background: Ibrutinib is the only Bruton tyrosine kinase inhibitor (BTKi) with once-daily oral capsule, tablet, and oral suspension formulations approved in the United States across indications of chronic lymphocytic leukemia/small lymphocytic lymphoma ...
Jonas Paludo, Lisa Nodzon, Xavier Woot de Trixhe, Michelle Pacia, Heena Mavani, Harisha Atluri, Thomas J. Huemann, Jessica Shelly, Yemin Liu, Shayna Sarosiek   +9 more
doaj   +1 more source

Rupture Test and Bioavailability of Oil-Soluble Vitamins [PDF]

, 2013
In lieu of an abstract, here is the article\u27s first paragraph: Bioavailability of multi-vitamins as dietary supplements has always been a concern. Dissolution studies have been successfully used to predict drug release of bioactive molecules, but with
Chablani, Lipika
core   +2 more sources