Results 11 to 20 of about 587,078 (311)

The Oral Microbiome and Cancer [PDF]

open access: yesFrontiers in Immunology, 2020
There is mounting evidence that members of the human microbiome are highly associated with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma (OSCC) is the most prevalent and most commonly studied, and it is the most common malignancy of the head and neck worldwide. However, there is a void regarding the role that the oral
Jorge Frias-Lopez   +2 more
openaire   +4 more sources

ATAD3A mediates activation of RAS-independent mitochondrial ERK1/2 signaling, favoring head and neck cancer development

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background Targeting mitochondrial oncoproteins presents a new concept in the development of effective cancer therapeutics. ATAD3A is a nuclear-encoded mitochondrial enzyme contributing to mitochondrial dynamics, cholesterol metabolism, and signal ...
Liwei Lang   +11 more
doaj   +1 more source

Tobacco addiction and it´s consequences on oral health of indigenous and rural people - a cross sectional study from central India

open access: yesTobacco Induced Diseases, 2018
Background Chewing of tobacco related stuff has gained the social acceptance due to which there is dramatic increase in the incidence of oral cancer and oral precancer. As we proceed more towards the rural areas incidence is increases.
Nandu Meshram   +3 more
doaj   +1 more source

A network meta-analysis assessing the effectiveness of various radical and conservative surgical approaches regarding recurrence in treating solid/multicystic ameloblastomas

open access: yesScientific Reports, 2023
Multiple treatment approaches have been undertaken to reduce the incidence of recurrence in solid/multicystic ameloblastoma (SMA), both conservative and radical. A network meta-analysis (NMA) was conducted to assess and compare the effectiveness of these
Faqi Nurdiansyah Hendra   +4 more
doaj   +1 more source

7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway

open access: yesCells, 2021
As the main derivative of paclitaxel, 7-Epitaxol is known to a have higher stability and cytotoxicity. However, the anticancer effect of 7-Epitaxol is still unclear.
V. Bharath Kumar   +7 more
doaj   +1 more source

Salvage surgery with second free flap reconstruction for recurrent oral squamous cell carcinoma

open access: yesHeliyon, 2020
Purpose: The purpose of this study was to evaluate the results of the reconstruction using the second free flap following resection of recurrent oral squamous cell carcinoma(OSCC).
Tae-Young Jung   +4 more
doaj   +1 more source

Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors

open access: yesCell Death and Disease, 2021
Human epidermal growth factor receptor 2 gene (HER2) is focally amplified in approximately 20% of breast cancers. HER2 inhibitors alone are not effective, and sensitizing agents will be necessary to move away from a reliance on heavily toxic ...
Konstantinos V. Floros   +10 more
doaj   +1 more source

Carcinogenic Effects of Areca Nut and Its Metabolites: A Review of the Experimental Evidence

open access: yesClinics and Practice, 2023
Oral cancers (OC) are among the most frequent malignancies encountered in Southeast Asia, primarily due to the prevalent habit of betel quid (BQ) and smokeless tobacco use in this region.
Kalpani Senevirathna   +6 more
doaj   +1 more source

A Comprehensive Review of Natural Products as Therapeutic or Chemopreventive Agents against Head and Neck Squamous Cell Carcinoma Cells Using Preclinical Models

open access: yesBiomedicines, 2023
Head and neck squamous cell carcinoma (HNSCC) is a type of cancer that arises from the epithelium lining of the oral cavity, hypopharynx, oropharynx, and larynx.
Yoon Xuan Liew   +2 more
doaj   +1 more source

Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress

open access: yesNature Communications, 2017
Cancer cell survival under metabolic stress is a critical step for metastasis. Here, the authors show that under glucose deprivation, Snail, a key regulator of the metastatic process, promotes survival by diverting glucose to the pentose phosphate ...
Nam Hee Kim   +20 more
doaj   +1 more source

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