Results 61 to 70 of about 1,279,624 (253)

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model. [PDF]

, 2017
An excessive requirement for methionine termed methionine dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by methionine deprivation such as with recombinant ...
Chmielowski, Bartosz, Dry, Sarah M, Eilber, Fritz C, Han, Qinghong, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Shukuan, Li, Yunfeng, Miyake, Kentaro, Murakami, Takashi, Nelson, Scott D, Russell, Tara A, Tan, Yuying, Unno, Michiaki   +15 more
core   +2 more sources

Interventions for treating oral mucositis for patients with cancer receiving treatment [PDF]

, 2010
Background Treatment of cancer is increasingly effective but is associated with short and long term side effects. Oral and gastrointestinal side effects, including oral candidiasis, remain a major source of illness despite the use of a variety of agents ...
Clarkson, Jan E., Furness, Susan, Khalid, Tasneem, McCabe, Martin, Meyer, Stefan, Worthington, Helen V.   +5 more
core   +8 more sources

A sex-dependent salivary bacterium influences oral mucositis severity after allogeneic hematopoietic cell transplantation

npj Biofilms and Microbiomes
The success of allogeneic hematopoietic cell transplantation (alloHCT) in curing hematologic disorders is limited by its short- and long-term toxicities.
Hakan Gem, Maryam Ebadi, Gale Sebastian, Rania Abasaeed, Michele Lloid, Samuel S. Minot, David R. Dean, Armin Rashidi   +7 more
doaj   +1 more source

Oxoglutarate Carrier Inhibition Reduced Melanoma Growth and Invasion by Reducing ATP Production

Pharmaceutics, 2020
Recent findings indicate that (a) mitochondria in proliferating cancer cells are functional, (b) cancer cells use more oxygen than normal cells for oxidative phosphorylation, and (c) cancer cells critically rely on cytosolic NADH transported into ...
Jae-Seon Lee, Jiwon Choi, Seon-Hyeong Lee, Joon Hee Kang, Ji Sun Ha, Hee Yeon Kim, Hyonchol Jang, Jong In Yook, Soo-Youl Kim   +8 more
doaj   +1 more source

Immunotherapy in oral cancer

Journal of Pharmacy And Bioallied Sciences, 2019
Immunotherapy is one of the newer entities which is promising, at least can be very much helpful as an adjuvant therapy. This newer modality of the treatment in the field of cancer treatment may be the fourth pillar supporting surgery, chemotherapy, and radiotherapy.
Sunil Paramel Mohan, Manoj K Bhaskaran, Ashford L George, Abhilash Thirutheri, Maya Somasundaran, Anegh Pavithran   +5 more
openaire   +3 more sources

Stability of standardized uptake values for quantitative bone SPECT for jawbone lesions: a single-center cross-sectional study

BMC Oral Health
Background The long time required for bone uptake of radiopharmaceutical material after injection for bone scintigraphy is a burden for patients with poor health.
Hironobu Hata, Satoshi Shimomura, Kenji Imamachi, Jun Sato, Takuya Asaka, Kenji Hirata, Kyousuke Funayama, Yoichi Mori, Masashi Matsuzaka, Toshikazu Nambu, Yoshimasa Kitagawa   +10 more
doaj   +1 more source

Oral Cancer

Journal of Student Research, 2022
Oral cancer or mouth cancer is a type of cancer that forms in the oral cavity, resulting in the uncontrolled growth of abnormal cells that damage the surrounding tissue. There are several factors that accelerate oral cancer, including human papillomavirus (HPV) infections, genetic influences, UV light and substance use.
Radaporn Chutanopmanee, Sirayawadee Maneesilp, Nonthasorn Wongsirilert, Jason Zhang   +3 more
openaire   +1 more source

Asiatic Acid, Extracted from Centella asiatica and Induces Apoptosis Pathway through the Phosphorylation p38 Mitogen-Activated Protein Kinase in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells

Biomolecules, 2020
Nasopharyngeal carcinoma (NPC) is an important issue in Asia because of its unique geographical and ethnic distribution. Cisplatin-based regimens are commonly the first-line used chemotherapy, but resistance and toxicities remain a problem.
Yen-Tze Liu, Yi-Ching Chuang, Yu-Sheng Lo, Chia-Chieh Lin, Yi-Ting Hsi, Ming-Ju Hsieh, Mu-Kuan Chen   +6 more
doaj   +1 more source

The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. [PDF]

, 2018
Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler\u27s diarrhea, the endogenous peptide hormones ...
Rappaport, Jeffrey A., Waldman, Scott A.
core   +2 more sources

Ultrasound-Guided Photoacoustic Imaging of Salivary Gland Hemodynamics in Rabbits

Photonics
Xerostomia (severe dry mouth) is a debilitating and often permanent side effect experienced by head and neck cancer patients due to radiation injury to salivary glands.
Eftekhar Rajab Bolookat, Vui King Vincent-Chong, Laurie J. Rich, Anurag K. Singh, Mukund Seshadri   +4 more
doaj   +1 more source