Results 71 to 80 of about 21,283 (244)

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

Cell Proliferation, EarlyView.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang, Miao Yu, Hangbo Liu, Kai Sun, Chenxin Geng, Haochen Liu, Hailan Feng, Yang Liu, Hu Zhao, Dong Han   +9 more
wiley   +1 more source

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, EarlyView.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

Immunohistochemical expression of SOX2 in oral normal epithelial, dysplasia and squamous cell carcinoma

Journal of Craniomaxillofacial Research, 2018
Objective: Oral squamous cell carcinoma (SCC) is an aggressive neoplasm with serious morbidity and mortality, which typically spreads through local invasive growth.
Pouria Motahhary, Mahnaz Sahebjamee, Maryam Nasimi, Zohreh Khodashenas, Fatemeh Hajian, Kambiz Kamyab   +5 more
doaj  

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Oral HPV-associated dysplasia: is koilocytic dysplasia a separate entity?

Frontiers in Oral Health
Oral epithelial dysplasia associated with high-risk HPV infection has received different names since its initial description, such as oral Bowenoid lesions, HPV-associated intraepithelial neoplasia, and oral koilocytic dysplasia.
Gabriela Anaya-Saavedra, Marcela Vázquez-Garduño   +1 more
doaj   +1 more source

Predicting Malignant Transformation in Oral Leukoplakia: A Multilayer Perceptron Approach Incorporating Clinicopathological Features and DNA Content

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) is a potentially malignant disorder of the oral mucosa. Accurate prediction of malignant transformation (MT) remains a clinical challenge. This study aimed to develop and evaluate a machine learning model that integrates histopathological, demographic, and DNA content features to predict MT risk in OL.
Guilherme Iani Pontes, Anna Luíza Damaceno Araújo, Andresa Borges Soares, Saman Warnakulasuriya, André Luis Santana de Freitas, Caroline Gennari Stevão, Marcelo Sperandio, Matheus Cardoso Moraes   +7 more
wiley   +1 more source

Integrated profiling reveals polarity protein dysregulation during oral cancer progression

Scientific Reports
Malignant transformation of oral precancerous lesions is a multistep process intricately linked to the disruption of epithelial cell polarity and activation of the epithelial–mesenchymal transition (EMT) program.
Sandip Ghose, U. Renuka Chaudry, Shouvik Chakravarty, Snehanjan Sarangi, Nidhan K. Biswas, Rathindranath Baral, Debarati Ray   +6 more
doaj   +1 more source

CHARACTERIZING HUMAN PAPILLOMAVIRUS ASSOCIATED ORAL EPITHELIAL DYSPLASIA

International Journal of Oral and Maxillofacial Surgery
The role of high-risk human papillomavirus (HR-HPV) is well documented in oropharyngeal squamous cell carcinoma and cervical cancer. Although a subset of oral dysplastic lesions have been associated to HPV infection as well, there is currently limited data characterizing these lesions.
openaire   +2 more sources

Remote Consultations for Monitoring Actinic Cheilitis: A Preliminary Non‐Randomized Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate the feasibility of remote consultation for monitoring actinic cheilitis. Materials and Methods A cross‐over, non‐randomized clinical trial comparing remote and in‐person consultations for patients with actinic cheilitis.
Mônica Simões Israel, Nathália de Almeida Freire, Bruno Teixeira Gonçalves Rodrigues, Yasmin Muniz Dias, Manoela Domingues Martins, Carlos Augusto Moreira de Sousa, Vinicius Coelho Carrard   +6 more
wiley   +1 more source

Epithelial mesenchymal transition and cancer stem cell markers in oral epithelial dysplasia and oral squamous cell carcinoma

Polish Journal of Pathology
The role of cancer stem cells (CSC) in oral cancer is widely accepted. Yet, the existence of CSC in dysplastic tissue and the molecular pathways of progression from dysplasia to malignancy remain to be explored.
Burcu Tokozlu, Özlem Özer Yücel, Sibel E. Gültekin, Leyla Arslan Bozdağ   +3 more
doaj   +1 more source