Results 31 to 40 of about 124,757 (203)

Open Oral Food Challenge in Adult with Food Allergy to Chicken Meat

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Food allergy is a hypersensitivity of the body's response to food. Food allergies are divided into three groups: immunoglobulin E (IgE) mediated, non-IgE mediated, and mixed IgE mediated with non-IgE mediated.
Yosi Charly, Cita Rosita SP, Trisniartami Setyaningrum   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Peanut thresholds in peanut‐allergic children are related to dietary composition

Immunity, Inflammation and Disease, 2023
Background There is no clear explanation for the large variation in threshold levels among peanut‐allergic children. We hypothesized that diet composition can partly explain this variation in thresholds, as nutrients and foods influence the intestinal ...
Daisy Luiten, Maarten Biezeveld, Olga vanDoorn, Hanae Riady, Ming Yang, Femke Bergsma, Atie van derPlas, Kim Brand, Nicolette Arends, Annette deBruin, Jeanne deVries, Tim deMeij, Berber Vlieg‐Boerstra   +12 more
doaj   +1 more source

Relationship between the diagnosis of food protein–induced enterocolitis syndrome and postemetic procalcitonin levels

Journal of Allergy and Clinical Immunology: Global, 2023
Background: There are no reports on the relationship between food protein–induced enterocolitis syndrome (FPIES) diagnosis and procalcitonin levels. Objective: Our study sought to demonstrate a correlation between the presence or absence and severity of ...
Chihiro Kunigami, MD, Takanori Imai, MD, PhD, Kosei Yamashita, MD, Toshiyuki Takagi, MD, Megumi Okawa, MD, Aiko Honda, MD, Yuki Okada, MD, PhD, Mayu Maeda, MD, PhD, Taro Kamiya, MD, PhD   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Standardization of oral food challenges as a method for diagnosis of food allergy in children of the Russian Federation: study protocol and preliminary results

Лечащий Врач
Background. Food allergy is a serious, life-threatening condition that negatively impacts the quality of life of patients and their families, especially among children.
D. M. Levina, S. O. Lukyanova, N. V. Zinovieva, Ju. V. Petrova, M. A. Rumyantsev, S. A. Konchina, E. I. Iakovleva, A. B. Chashchukhina, A. I. Kolotilina, I. A. Korsunskiy, D. B. Munblit, I. I. Afukov, A. A. Korsunskiy, L. A. Fedorova   +13 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source