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Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test [PDF]

Frontiers in Endocrinology, 2018
IntroductionImpaired glucose tolerance (IGT) is diagnosed by a standardized oral glucose tolerance test (OGTT). However, the OGTT is laborious, and when not performed, glucose tolerance cannot be determined from fasting samples retrospectively. We tested
Rohit Babbar, Rohit Babbar, Martin Heni, Martin Heni, Martin Heni, Andreas Peter, Andreas Peter, Andreas Peter, Martin Hrabě de Angelis, Hans-Ulrich Häring, Hans-Ulrich Häring, Hans-Ulrich Häring, Andreas Fritsche, Andreas Fritsche, Andreas Fritsche, Hubert Preissl, Hubert Preissl, Hubert Preissl, Bernhard Schölkopf, Róbert Wagner, Róbert Wagner, Róbert Wagner   +21 more
doaj   +8 more sources

Predicting isolated impaired glucose tolerance without oral glucose tolerance test using machine learning in Chinese Han men [PDF]

Frontiers in Endocrinology
BackgroundIsolated Impaired Glucose Tolerance (I-IGT) represents a specific prediabetic state that typically requires a standardized oral glucose tolerance test (OGTT) for diagnosis.
Lin Wang, Jing Xie, Zhaoyan Gu, Xinyu Miao, Lichao Ma, Shuangtong Yan, Yanping Gong, Chunlin Li, Banruo Sun, Yue Ruan   +9 more
doaj   +2 more sources

Abnormal glucose tolerance in children: oral glucose tolerance test is fit-for-purpose

Exploration of Medicine, 2023
Aim: Childhood obesity is accompanied by an increased prevalence of abnormal glucose tolerance (AGT) including the prediabetes states. This study aims to investigate and evaluate the use of oral glucose tolerance test (OGTT) for detecting AGT among ...
Vivian Yuet Ho Law, Jack Hong Ming Young, Hak Yung Ng, Louis Tsz Wang Chan   +3 more
doaj   +1 more source

Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study: TEFA

Endocrinology, Diabetes & Metabolism, 2021
Aim The aim of the present study was to assess beta cell function based on an oral glucose tolerance test (OGTT) in participants with single islet autoantibody or an intravenous glucose tolerance test (IvGTT) in participants with multiple islet ...
Maria Månsson Martinez, Falastin Salami, Helena Elding Larsson, Jorma Toppari, Åke Lernmark, Jukka Kero, Riitta Veijola, Jaakko J Koskenniemi, Päivi Tossavainen, Markus Lundgren, Henrik Borg, Anastasia Katsarou, Marlena Maziarz, Carina Törn, The TEDDY Family (TEFA) Study Group   +14 more
doaj   +1 more source

Comparison of continuous glucose monitoring to reference standard oral glucose tolerance test for the detection of dysglycemia in cystic Fibrosis: A systematic review

Journal of Clinical & Translational Endocrinology, 2022
Aims: Increasing evidence for benefit of early detection of cystic fibrosis related diabetes (CFRD) coupled with limitations of current diagnostic investigations has led to interest and utilisation of continuous glucose monitoring (CGM).
Shanal Kumar, Michael Pallin, Georgia Soldatos, Helena Teede   +3 more
doaj   +1 more source

High variability in oral glucose tolerance among 1,128 patients with cystic fibrosis: a multicenter screening study. [PDF]

PLoS ONE, 2014
In cystic fibrosis, highly variable glucose tolerance is suspected. However, no study provided within-patient coefficients of variation. The main objective of this short report was to evaluate within-patient variability of oral glucose tolerance.In total,
Nicole Scheuing, Reinhard W Holl, Gerd Dockter, Julia M Hermann, Sibylle Junge, Cordula Koerner-Rettberg, Lutz Naehrlich, Christina Smaczny, Doris Staab, Gabriela Thalhammer, Silke van Koningsbruggen-Rietschel, Manfred Ballmann   +11 more
doaj   +1 more source

DA-1241, a Novel GPR119 Agonist, Improves Hyperglycaemia by Inhibiting Hepatic Gluconeogenesis and Enhancing Insulin Secretion in Diabetic Mice [PDF]

Diabetes & Metabolism Journal, 2022
Background We investigated the antidiabetic effects of DA-1241, a novel G protein-coupled receptor (GPR) 119 agonist, in vitro and in vivo. Methods DA-1241 was administrated to high-fat diet (HFD)-fed C57BL/6J mice for 12 weeks after hyperglycaemia ...
Youjin Kim, Si Woo Lee, Hyejin Wang, Ryeong-Hyeon Kim, Hyun Ki Park, Hangkyu Lee, Eun Seok Kang   +6 more
doaj   +1 more source

Carbohydrate Intake Prior to Oral Glucose Tolerance Testing [PDF]

Journal of the Endocrine Society, 2021
Abstract With the emergence of glycated hemoglobin as a diagnostic test for diabetes, oral glucose tolerance tests (OGTTs) have become rare in endocrinology practice. As they have moved out of favor, the importance of patient instructions on preparation prior to OGTT has faded from memory.
Klara R Klein, Christopher P Walker, Amber L McFerren, Halie Huffman, Flavio Frohlich, John B Buse   +5 more
openaire   +2 more sources

Acromegaly with initial negative oral glucose tolerance test: a case report

Journal of Medical Case Reports, 2023
Background Acromegaly can be diagnosed by a growth hormone value ≥ 1 µg/L following an oral glucose tolerance test. However, normal growth hormone suppression following oral glucose tolerance test may not exclude acromegaly.
Wen-Hsuan Tsai, Ming-Nan Chien, Shuen-Han Dai, Yun-Kai Chan   +3 more
doaj   +1 more source