Results 61 to 70 of about 107,836 (304)

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Characterisation of linear predictability and non-stationarity of subcutaneous glucose profiles [PDF]

, 2013
Continuous glucose monitoring is increasingly used in the management of diabetes. Subcutaneous glucose profiles are characterised by a strong non-stationarity, which limits the application of correlation-spectral analysis.
Khovanov, IA, Holt, Tim A., Khovanov, I. A., Khovanova, N. A., Griffiths, F, Holt, TA, Sbano, L., Griffiths, Frances, Khovanova, NA, Sbano, L   +9 more
core   +1 more source

Oral Glucose Tolerance Test for Universal screening for Gestational Diabetes Mellitus

Journal of Nepal Health Research Council
Background: Gestational Diabetes Mellitus increased almost 30% in many countries, including underdeveloped countries and same in Nepal. Hospital-based studies in Nepal reported Gestational Diabetes Mellitus cases, with prevalence 2.48% in 2010 to 4.47 ...
Abha Shrestha, Rajani Shakya, Rabina Shrestha, Sulata Karki, Seema Das, Priya Shrestha, Anisha Rai, Saroj Thapa, Abha Shrestha, Biraj Karmacharya   +9 more
doaj   +1 more source

Effect of Ethyl Acetate Extract of Melothria Perpusilla on Oral Glucose Tolerance Test in Albino Rats [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Diabetes mellitus is a group of common metabolic disorders sharing the phenotype of hyperglycaemia. Certain disadvantages like side effects or less efficacy limit the optimal use of antidiabetic drugs.
Shailendra Vikram Jitendra Singh, Usham Dharmaraja Meetei, Subhalakshmi Devi Akham, Rita Devi Sanjenbam   +3 more
doaj   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Anthropometry, glucose tolerance and insulin concentrations in South Indian children: relationships to maternal glucose tolerance during pregnancy [PDF]

, 2005
Earlier studies have shown that individuals whose mothers were diabetic when they were in utero, have an increased risk of early obesity, and impaired glucose tolerance (lGT) and type 2 diabetes in adult life.
Krishnaveni, Ghattu Vedamurthy
core  

Prolactin [PDF]

, 1977
During an oral glucose tolerance test (OGTT) glucose and insulin levels were measured in 26 patients with prolactin-producing pituitary tumours without growth hormone excess.
Hörl, R., Weissmann, A., Landgraf, Rüdiger, Landgraf-Leurs, Martina M. C., Scriba, Peter Christian, Werder, Klaus von   +5 more
core   +1 more source

Oral Glucose Tolerance Test in Pregnancy and Subsequent Maternal Hypertension [PDF]

, 2023
OBJECTIVE: The aim of the study is to evaluate whether values and the shape of the glucose curve during the oral glucose tolerance test (OGTT) in pregnancy identify women at risk of developing hypertension (HTN) later in life. STUDY DESIGN: This category
Wapner, Ronald J, Thorp, John M, Casey, Brian M, Blackwell, Sean C, Rouse, Dwight J, Chien, Edward K, Varner, Michael W, Tita, Alan T, Rice, Madeline Murguia, Reddy, Uma M, Costantine, Maged M, Peaceman, Alan M, Landon, Mark B   +12 more
core   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Estimation of insulin sensitivity from continuous glucose monitoring and insulin pump data in type 1 diabetes [PDF]

, 2012
Diabetes mellitus is a disease characterized by chronic hyperglycemia either due to a lack of secretion of the hormone insulin (Type 1 Diabetes Mellitus, T1DM) or due to impaired action of this hormone (Type 2 Diabetes Mellitus, T2DM).
Ronca, Gabriele
core