Results 81 to 90 of about 8,938,532 (295)

Oral glucose tolerance test responses.

, 2015
Plasma glucose (A) and insulin (B) concentrations during an oral glucose tolerance test, including corresponding total area under the curve (AUC, C and D, respectively) before and after HIT or MICT.
Cecilie Thøgersen-Ntoumani (799772), Oliver J. Wilson (799770), Ahmed M. Adlan (799773), Alexandra S. Taylor (799771), Anton J. M. Wagenmakers (799774), Sam O. Shepherd (799769), Christopher S. Shaw (349585)   +6 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

Journal of Diabetes Investigation, 2020
Aims/Introduction An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear.
Mikiko Okazaki‐Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, Hitoshi Sugihara   +5 more
doaj   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Ocorrência de diabetes melito em mulheres com hiperglicemia em gestação prévia Prevalence of diabetes mellitus in women with prior gestational hyperglycemia

Revista de Saúde Pública, 2003
OBJETIVO: Verificar a freqüência com que ocorria intolerância à glicose (diabetes melito e tolerância à glicose diminuída) em mulheres cuja gestação foi acompanhada e avaliada quanto à tolerância à glicose. MÉTODOS: Num período de até 12 anos da gestação-
Márcia Rocha Gabaldi Silva, Iracema de Mattos Paranhos Calderon, Luciana Colnago Gonçalves, Flávio Ferrari Aragon, Carlos Roberto Padovani, Walkyria de Paula Pimenta   +5 more
doaj   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Postprandial change in glucose level from baseline (mean ± SEM) during an oral glucose tolerance test.

, 2019
The fasting glucose level was used a baseline and the change in glucose level is plotted over time for 2.5 hours of the oral glucose tolerance test. Treatments for the oral glucose tolerance test include 50 gram glucose solution either alone (□), with ...
Sofia Feng Godinez (6519671), Ondulla T. Toomer (6519674), Jonathan C. Allen (526966), Lisa L. Dean (6519668), Lindsey M. Christman (6519665)   +4 more
core   +1 more source

Characterisation of linear predictability and non-stationarity of subcutaneous glucose profiles [PDF]

, 2013
Continuous glucose monitoring is increasingly used in the management of diabetes. Subcutaneous glucose profiles are characterised by a strong non-stationarity, which limits the application of correlation-spectral analysis.
Khovanov, IA, Holt, Tim A., Khovanov, I. A., Khovanova, N. A., Griffiths, F, Holt, TA, Sbano, L., Griffiths, Frances, Khovanova, NA, Sbano, L   +9 more
core   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source