Results 101 to 110 of about 8,938,532 (295)
The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John +4 more
wiley +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
Structural identifiability and indistinguishability analyses of glucose-insulin models [PDF]
In this thesis, the structural identifiability analyses of established and novel glucose-insulin models was performed, to determine whether the models are globally structurally identifiable with the observations available.
Chin, Sze Vone
core
Expert Consensus on the Management of Obesity in Older Adults (2026 Edition)
This graphical abstract summarizes a safety‐first framework for managing obesity in older adults, with attention to age, functional status, comorbidities, and sarcopenia risk. Key assessments include BMI, waist measures, body fat percentage, skeletal muscle mass, and comprehensive geriatric evaluation. Management prioritizes reducing visceral fat while
Qi Pan, Lixin Guo
wiley +1 more source
Influence of Hypoglycemia During The 100-G Oral Glucose Tolerance Test on Obstetrics Outcomes
OBJECTIVES: We aimed to investigate the impact of hypoglycemia during 100-g oral glucose tolerance test on perinatal outcomes. STUDY DESIGN: Obstetrics records of 411 pregnants who delivered singletons at our institution were reviewed.
İlknur İnegöl Gümüş +5 more
doaj
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi +12 more
wiley +1 more source
Objective: To compare universal screening of pregnant ladies for Gestational Diabetes Mellitus (GDM) with selective high risk screening by one step Oral Glucose Tolerance Test (OGTT) at 24-28 weeks pregnancy. Study Design: Comparative cross-sectional
Humaira Tariq +4 more
doaj +2 more sources
Levels of blood glucose and blood insulin during an oral glucose tolerance test.
A) Blood glucose levels during an oral glucose tolerance test in male wt mice (open circles) and male hSAA1 mice (filled squares) fed with HFD. B) Blood glucose area under the curve (AUC) in male mice fed with HFD.
Kajsa Sjöholm (351309) +4 more
core +1 more source
Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu +5 more
wiley +1 more source
Glucose values during oral glucose tolerance test (OGTT) in the presence and absence of metformin.
Shown are mean ± standard deviation for A) blood glucose (mmol/L) prior to and during the SUGAR-MGH oral glucose tolerance test (OGTT) stratified by participants who took no metformin doses (blue dashed line with blue circles) and participants who took ...
Alisa K. Manning (110227) +33 more
core +1 more source

